태평성혜방과 동인침구경의 침구금기혈에 대한 고찰

권선오,김승태 경락경혈학회 2018 Korean Journal of Acupuncture Vol.35 No.1

Objectives : This research aimed to verify the validities of contraindicated acupoints in acupuncture or moxibustion treatments in Taipingshenghuifang and Tongrenzhenjiujing. Methods : We investigated contraindicated acupoints when performing needling or moxibustion in Taipingshenghuifang and Tongrenzhenjiujing, then verified them in various literatures and today's medical knowledge. Results : In Taipingshenghuifang and Tongrenzhenjiujing, 15 acupoints were described to need a careful approach in acupuncture treatment, and 24 acupoints were described so in moxibustion treatment in common. And additionally GB1 was described to need a careful moxibustion treatment in Taipingshenghuifang. Most of the descriptions for the contradindicated acupoints can be explained based on medical knowledge. Conclusions : The contraindicated acupoints in acupuncture or moxibustion treatments in Taipingshenghuifang and Tongrenzhenjiujing seem to have been classified based on the experience of the doctors at that time. Therefore they may be referred to for safe acupuncture or moxibustion treatments at these points.

산삼과 인삼 메탄올 추출물 아만성 복용의 Mice Tail Suspension Test에서의 항우울 효과에 대한 비교연구

권선오,최수민,김명환,이봄비,박무원,이혜정,박히준,함대현 대한침구의학회 2009 대한침구의학회지 Vol.26 No.4

Objectives : The antidepressant effect of the subchronic administration of the methanolic extract of wild‐ginseng(WG) was investigated compared with that of cultivated ginseng(CG, panax ginseng) extract. Methods : To assess the antidepressant effect of the ginseng extracts, tail suspension test(TST) was executed in mice after daily administration of WG or CG extract for five consecutive days. Results : The WG extract at daily dose of 600mg/kg significantly reduced the total duration of immobility in the TST, whereas there was no significant reduction at daily dose of 300mg/kg WG and 600mg/kg CG. There were no individual differences between experimental groups in open field test (OFT) to evaluate psychostimulant effects of WG or CG extract. In the high performance liquid chromatography(HPLC) analysis of the extracts, it was found that WG included four times more ginsenoside Rg1 and Re, three times more Rf, and six times more Rb1 and Rc than CG. Conclusions : It is suggested that WG extract has stronger antidepressant effect than CG extract, which means it includes more antidepressant compounds than CG.

육총혈에 배속되는 경혈에 관한 연구

권선오 ( Sunoh Kwon ),서병관 ( Byung Kwan Seo ),김승태 ( Seungtae Kim ) 대한경락경혈학회 2016 Korean Journal of Acupuncture Vol.33 No.2

Objectives : Six command points are individual points that have strong and broad effects on their related part of the body, but there is a controversy about which acupoints are should be included in the six command points. This research was reviewed which acupoints are suitable for the construction of the six command points. Methods : We searched acupoints mentioned six command points in literatures, then investigated the effects of the acupoints to identify that they can be included in the six command points. And we deliberated which acupoints are suitable for the six command points. Results : Acupoints mentioned the six command points are LU7, LI4, ST36, BL40, PC6, TE6, GV26, ouch point, GB34 and SP6. Among the acupoints, LU7, LI4, ST36, BL40 and PC6 was included in the six command points in all of searched literatures. And GV26, ouch point, GB34 and SP6 were excluded because GV26 and ouch point were not fit the definition of the six command points, ST36 can be an alternative to SP6 based on their effects, and GB34 has a similar but little effect compared to TE6. Conclusions : Based on the definition of six command points and the effect of the acupoints, we suggest that the six command points should be composed of LU7, LI4, ST36, BL40, PC6 and TE6.

『비급천김요방(備急千金要方)』과 『천김익방(千金翼方)』의 침구금기혈(鍼灸禁忌穴) 연구

권선오 ( Sun Oh Kwon ),서병관 ( Byung Kwan Seo ),박히준 ( Hi Joon Park ),함대현 ( Dae Hyun Hahm ),이혜정 ( Hye Jung Lee ),김승태 ( Seung Tae Kim ) 경락경혈학회 2011 Korean Journal of Acupuncture Vol.28 No.1

Objectives: To classify needling or moxibustion-prohibited acupoints in Emergency Formulas Worth a Thousand in Gold (EFWTG) and Supplement to the Formulas Worth a Thousand in Gold (SFWTG). Methods: We found needling or moxibustion-prohibited acupoints in EFWTG and SFWTG, then investigated the influences of needling or moxibustion-prohibited acupoints on A-B Classic of Acupuncture and Moxibustion. Results: In EFWTG, the needling-prohibited points were LI13, ST17, BL56, TE8, CV8, CV15 and GV24. Acupoints needed careful needling were LU2, ST12, KI2, KI7, TE19, GB3 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST8, ST9, ST17, ST32, ST33, BL6, BL30, TE18, TE23, GB33, GB42, CV5, CV15, GV6, GV15, GV16 and GV17. Acupoints needed careful moxibustion were ST7, ST30, TE21 and GB22. In SFWTG, the needling-prohibited points were LU2, LI13, ST12, ST17, ST32, BL56, KI2, KI7, TE8, TE19, GB3, CV8, CV15, GV24 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST9, ST17, ST30, ST32, ST33, BL6, BL30, TE18, TE23, GB22, GB33, GB42, CV5, CV15, GV6, GV15, GV16, GV17 and ijung. Conclusions: There were 7 needling-prohibited points, 7 acupoints needed careful needling, 20 moxibustion-prohibited points, and 4 acupoints needed careful needling in EFWTG, and 15 needling-prohibited points and 24 moxibustion-prohibited points in SFWTG. The needling or moxibustion-prohibited acupoints in A-B Classic of Acupuncture and Moxibustion had a strong influence on those in the two literatures.

침구갑을경(鍼灸甲乙經) 침구금기혈(鍼灸禁忌穴) 대한 소고(小考)

권선오 ( Sun Oh Kwon ),김승태 ( Seung Tae Kim ),서병관 ( Byung Kwan Seo ),박히준 ( Hi Joon Park ),함대현 ( Dae Hyun Hahm ),이혜정 ( Hye Jung Lee ) 대한경락경혈학회 2010 Korean Journal of Acupuncture Vol.27 No.2

Objectives: To investigate the meaning and the importance of needling or moxibustionprohibited acupoints in Chimgugapeulgyeong(鍼灸甲乙經). Methods: We found needling or moxibustion-prohibited acupoints in Chimgugapeulgyeong, then investigated the causes of the prohibitions from the various Literatures and the anatomical structures near the acupoints. Results: In Chimgugapeulgyeong, the needling and moxibustion-prohibited points were ST9, ST17, ST32, CV5, and CV15. The needling-prohibited points were LU2, LI13, ST12, BL56, KI2, KI7, TE8, TE19, GB3, CV8, GV24, and jwagak(左角). The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST30, ST33, BL5, BL6, BL15, BL30, TE18, TE21, TE23, GB22, GB33, GB42, GV6, GV15, GV16, GV17 and GV25. The major cause of developing prohibited needling or moxibustion was due to the possibility to damage vessels or organs near them; other causes were side effects brought by applying wrong stimulating method or inducing women sterilized. Conclusions: The prohibition of needling or moxibustion on the points found in Chimgugapeulgyeong had acceptable causes. Therefore the techniques of needling or moxibustion on the acupoint should be performed with care.

한국의 전침연구 동향 분석

권선오 ( Sunoh Kwon ),이정원 ( Jeong Won Lee ),김승태 ( Seungtae Kim ) 경락경혈학회 2018 Korean Journal of Acupuncture Vol.35 No.3

Objectives : Electroacupuncture is a procedure in which pulses of weak electrical current are sent through acupuncture needles into acupuncture points in the skin. Since the 1970s, electroacupuncture has been widely used for treating various diseases including pain, inflammatory diseases and neurodegenerative diseases and electroacupuncture research has also been actively conducted in Korea. This study was designed to assess the tendencies and research performances in Korea. Methods : Articles referring to electroacupuncture in Korea were searched in Korean Studies Information Service System, Oriental Medicine Advanced Searching Integrated System, DBpia, Pubmed and Scopus, and assessed by distribution of document types, published articles, source institutes, journals, and subject categories. Results : Total 677 articles were included in this study. Among them, basic researches were 395, clinical researches were 210, reviews were 68 and others were 4. Kyung Hee university published the most articles, followed by Wonkwang univresity, Daejeon university and Pusan national university in Korean institutes. Journal of Acupuncture Research published the most articles, followed by Korean Journal of Acupuncture, Journal of Korean medicine rehabilitation and Journal of physiology & pathology in Korean medicine among journals. Animals were used in the most articles, followed by human, literatures and protocol in subject categories. The number of articles per year was related to the increase of research fund and the number per institution was related to the number of professors and researchers. Conclusions : In order to carry out better electroacupuncture researches, it is necessary to cultivate electroacupuncture researchers and increase in research funds.

의학입문에 수록된 금침혈 연구

채광민,권선오,윤동학,김승태 경락경혈학회 2019 Korean Journal of Acupuncture Vol.36 No.3

Objectives : The authors aimed at contributing to the safety of acupuncture in the clinic by analyzing the information of contraindicated acupoints described in Uihakipmun. Methods : We investigated the contents related acupuncture contraindications in Uihakipmun, categorized the contraindicated acupoints by site and identified whether they can cause adverse events from the anatomical point of view. Results : In Uihakipmun, 49 acupoints - BL6, BL8, BL9, ST1, SI18, BL1, BL2, TE18, TE19, TE20, GB1, GB3, GV22, GV24, ST12, ST9, TE16, GV6, BL15, BL30, CV17, LU2, GB22, SP16, CV8, CV9, CV15, KI11, ST30, SP11, BL56, GB32, GB33, GB42, LI13, HT2, TE8, GV17, GB18, EX-HN11, GB21, GV11, GV10, ST17, CV5, CV1, ST42, SP6, LI4 - were described as contraindicated acupoints. Among them, the contraindications induced by acupuncture treatment were described for just 5 acupoints. Anatomically, acupuncture stimulation at the contraindicated acupoints can cause organ, nerve or vessel damage near the acupoints. And the number of contraindicated acupoints in Uihakipmun was increased compared to those in Hwangjenaegyeong, Chimgugabeulgyeong, Bigeupcheongeumyobang, Donginsuhyeolchimgudogyeong and Chimgujasaenggyeong. Conclusions : In Ming dynasty, the knowledge associated with adverse events on acupuncture was increased by the accumulation of medical knowledge. Acupuncture stimulation at the contraindicated acupoints described in Uihakipmun can cause tissue damage, therefore we should perform acupuncture procedure carefully to avoid adverse events when stimulating the contraindicated acupoints.

Inhibitory Effect of Sowthistle (Ixeris dentata) on Development and Expression of Behavioral Locomotor Sensitization to Nicotine in Rats

이봄비,박진희,권선오,염미정,서봉준,심인섭,이혜정,윤석후,정동명,함대현 한국식품과학회 2012 Food Science and Biotechnology Vol.21 No.3

The aim of this study was to investigate the effects of sowthistle (Ixeris dentata, IXD) on development and expression of nicotine-induced locomotor sensitization and underlying neuronal activation reflected by c-Fos expression in rats. Rats were pretreated with IXD 30 min before a daily injection of nicotine during an 8-day development phase and then challenged with nicotine after a 6-day withdrawal period. In another set of experiments,same IXD doses were administered once 30 min before nicotine challenge. Daily IXD treatment during development phase was not effective in blocking nicotine-induced locomotor sensitization in rats. However, a single IXD treatment after the development and withdrawal periods of nicotine sensitization significantly alleviated sensitized locomotor behavior on day 15. These behavioral results were coincident with significant inhibition of nicotineinduced c-Fos expression in the nucleus accumbens. These results indicated that IXD pretreatment significantly blocked the expression, but not the development of nicotine-induced locomotor sensitization in rats.

Chronic Administration of Baicalein Decreases Depression-Like Behavior Induced by Repeated Restraint Stress in Rats

이봄비,서봉준,박진희,김성훈,권선오,염미정,심인섭,이혜정,함대현 대한약리학회 2013 The Korean Journal of Physiology & Pharmacology Vol.17 No.5

Baicalein (BA), a plant-derived active flavonoid present in the root of Scutellaria baicalensis, has been widely used for the treatment of stress-related neuropsychiatric disorders including depression. Previous studies have demonstrated that repeated restraint stress disrupts the activity of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression. The behavioral and neurochemical basis of the BA effect on depression remain unclear. The present study used the forced swimming test (FST) and changes in brain neurotransmitter levels to confirm the impact of BA on repeated restraint stress-induced behavioral and neurochemical changes in rats. Male rats received 10, 20, or 40 mg/kg BA (i.p.) 30 min prior to daily exposure to repeated restraint stress (2 h/day) for 14 days. Activation of the HPA axis in response to repeated restraint stress was confirmed by measuring serum corticosterone levels and the expression of corticotrophin-releasing factor in the hypothalamus. Daily BA administration significantly decreased the duration of immobility in the FST, increased sucrose consumption, and restored the stress-related decreases in dopamine concentrations in the hippocampus to near normal levels. BA significantly inhibited the stress-induced decrease in neuronal tyrosine hydroxylase immunoreactivity in the ventral tegmental area and the expression of brain-derived neurotrophic factor (BDNF) mRNA in the hippocampus. Taken together, these findings indicate that administration of BA prior to the repeated restraint stress significantly improves helpless behaviors and depressive symptoms, possibly by preventing the decrease in dopamine and BDNF expression. Thus, BA may be a useful agent for the treatment or alleviation of the complex symptoms associated with depression.

부항 시술에 의해 형성된 수포에 관한 고찰

윤혜연 ( Hye Yeon Yun ),권선오 ( Sun Oh Kwon ),김승태 ( Seung Tae Kim ),박히준 ( Hi Joon Park ),함대현 ( Dae Hyun Hahm ),이혜정 ( Hye Jung Lee ) 경락경혈학회 2011 Korean Journal of Acupuncture Vol.28 No.3

Objectives : The aims of this study were to evaluate a blister caused by cupping. Methods : We searched relevant case reports, survey, and review articles using databases of online bibliography. Results : 1. The fluid in the blister caused by cupping therapy is normal substance by laboratory analysis. The fluid has no signs of infection in the culture, Gram stain, or tissue biopsy 2. In histological finding, the blister caused by cupping therapy is made by dermo-epidermal seperation at subcellular level. Suction blistering was neither inflammatory nor autolysis activation of lysosomal hydrolases. 3. Blistering times directly, related to suction pressure. Suction blister formation time is accelerated in older subjects compared with younger individuals and higher temperature was more susceptable to the blister compared with lower temperature. The flexor aspect of forearm is a easy site for suction blister formation compared with leg and abdominal site. 4. Blister caused by cupping therapy is treated by regular and judicious changes of sterile dressing over several weeks. The vesicles healed well and left no visible scar. Conclusions : Blister caused by cupping therapy is artificially controlled by doctor``s therapeutic purpose. Blister is not histologically injurious to health and the blister is a natural concomitant after cupping therapy.