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      • KCI등재

        우울장애에 대한 인지행동치료의 최근 연구동향

        김정범,이상희 한국인지행동치료학회 2006 인지행동치료 Vol.6 No.2

        경도 혹은 중등도의 급성 우울증에 있어 인지행동치료의 치료 효과는 그동안 상당히 경험적인 지지를 받아 왔다. 최근에는 심하거나 만성적인 우울증 치료, 재발 방지, 약물과의 병합이득에서 인지행동치료의 유용성에 초점을 맞추어 연구되고 있다. 더욱 최근에는 컴퓨터 기술과 대중매체의 발달에 편승하여 독서치료와 컴퓨터 치료와 같은 자가치료도 시행되고 있다. 심리치료의 혁신적인 치료법이라 할 수 있는 마음챙김 명상에서는 전통적인 인지행동치료와 통합되어 변화와 수용에 근거한 전략이 가미되었다. 이 논문은 매일매일 일상의 임상적 진료에서 인지행동치료의 역할을 파악하기 위해 이와 같은 인지행동치료와 관련된 최근의 중요 이슈에 관한 경험적 자료를 명료화하고자 한다 There is considerable empirical support for the use of cognitive behavior therapy(CBT) in the treatment of mild to moderately severe acute major depression. More recent research has focused in the utility of this approach in severe or chronic depressive disorders, in relapse prevention and also on the potential benefits of combining CBT with medication. More advanced technologies make the media used to deliver self-administered treatments including bibliotherapy and computer-based treatments much broader. Recent innovations in psychological treatment have integrated mindfulness meditation techniques with traditional CBT, including acceptance- and change-based strategies. This paper attempts to clarify the empirical data on these important issues in order to identify further the role of CBT in day-to-day clinical practice.

      • KCI등재

        신생 흰쥐 난형낭의 조직 배양 모델에서 저출력 레이저의 Gentamicin 이독성 예방과 치료 효과

        김정범,정재윤,안진철,이정구,오양희 대한이비인후과학회 2009 대한이비인후과학회지 두경부외과학 Vol.52 No.1

        Background and Objectives:The purpose of this study was to investigate the effects of low level laser for the prevention and treatment of aminoglycoside-induced vestibular ototoxicity. Materials and Method:An organotypic culture of 2 to 4 days old rat utricular maculae was established. Rats were divided into 6 groups according to the treadtment of the utricles:G (gentamicintreated), L (laser-irradiated), LG (laser-irradiated and gentamicin-treated), GL (gentamicin-treated and laser-irradiated), LGL (gentamicin-treated during laser-irradiated) and C (control). After organotypic culture, the utricles of 6 groups were examined by confocal laser scanning electron microscope and scanning electron microscope. The results of each group were compared with each other by statistical methods. Results:The number of vestibular hair cells of the group G was smaller compared to that of the group C. The group L had no difference compared with the group C. The groups LG and GL showed more vestibular hair cells compared with the group G. The group LG showed more vestibular hair cells than the group GL. The group LGL showed most vestibular hair cells compared to that of the groups G, LG, and GL. Conclusion:The most effective treatment of aminoglycosideinduced vestibular otoxicity is the irradiation of low level laser before and after the insult of the aminoglycoside. Further clinical studies using low level laser were needed to prevent aminoglycoside-induced ototoxicity and to promote the regeneration of vestibular hair cells.

      • 공황장애의 평가

        김정범 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.2

        The four general areas to be evaluated in cases of panic disorder are (1) medical status, (2) phenomenology and history of panic auld agoraphobia, (3) comorbidity and history of other psychiatric disorders, and (4) predisposing and precipitating factors for panic attacks and factors maintaining the panic disorder. The assessment also involves information about how panic-disordered individuals behave on the five major response systems and their interaction: cognitive, behavioral, affective, physiological, and social. In order to tap into these different areas and response systems, clinicians should use a variety of measurement techniques: clinical interviews, self-report scales, self-monitoring, behavioral observation, psychophysiological monitoring. The use of a simple, psychometrically sound instrument such as Panic Disorder Severity Scale(PDSS), which considers all of the essential domains of panic disorder, will provide clinicians with an appropriate measure for diagnosing and monitoring patients. The application of this more comprehensive scale for monitoring patient should alert clinicians to reemergence of associated symptoms of panic disorder and allow for the rapid modification of treatment. All of the investigators who conduct any study of panic disorder should consider the essential, recommended, optional measures agreed in Consensus Development Conference on the treatment of panic disorder in 1992 and implement them in their research. Then the results of study from different laboratories will be easier to compare.

      • 桃仁承氣湯과 柱枝茯笭丸이 瘀血病態에 미치는 藥力比較硏究

        金楨犯 世明대학교 한의학연구소 1999 韓醫學硏究所 論文集 Vol.2 No.-

        In order to compare the effects of Doinseunggitang and Kyejibokryonghwan on both 'dextran-induced blood stasis model(Dx Model)' and 'hydrocortisone acetate(HA)-induced blood stasis model(HA Model)', rats of Dx Model treated with 10% dextranaqueous solution (i.v.injection, 1.1㎖/200g/day through caudal vein, once) were orally administrated liquid extract of Doinseunggitang and Kyejibokryonghwan, and then observed platelet, fibrinogen, prothrombin time, hematocrit and FDP level. Another rats of HA Model (i.m.injection, 5mg/200g/day into the muscular rump, for 7 days) were orally administrated liquid extract of Doinseunggitang and Kyejibokryonghwan, thereafter measured platelet, fibrinogen, prothrombin time and hematocrit. The results were summarized as follows: 1.Platelet was stitistically significantly increased in Doinseunggitang group than Kyejibokryonghwan Group on both Dx Model and HA Model. 2.Fibrinogen Level was increased in Doinseunggitang group than Kyejibokryonghwan Group on both Dx Model and HA Model. 3.Prothrombin time was shortened in Doinseunggitang group than Kyejibokryonghwan Group on both Dx Model and HA Model. 4.Hematocrit was stitistically significantly increased in Doinseunggitang group compared with data of control group on Dx Model, but was decreased on HA Model. 5.FDP was more decreased in Doinseunggitang group than Kyejibokryonghwan Group on Dx Model.

      • KCI등재

        스토리텔링을 활용한 지역 관광콘텐츠 개선 방향에 관한 연구 - 강원도 고성군 ‘화진포의 성’을 중심으로 -

        김정범,한호 한국문화공간건축학회 2015 한국문화공간건축학회논문집 Vol.- No.50

        Due to the changes in modern people's value system, today's sightseeing, unlike that of the past, requires unique experiences on tourists. Therefore, there are growing needs on experiential factors called tourism storytelling. This study is to discuss the improvement direction for contents of sightseeing storytelling on tourist sites on subject of 'Castle of Hwajinpo' in Goseung-gun, Gangwon-do Province. For the purpose, we visited tourists sites in Korea that are similar to 'Castle of Hwajinpo' and made an analysis in order to seek improvements in 'Castle of Hwajinpo'. For methods of analysis, first, we conducted a research on cases of similar tourist sites in Korea with historical or religious background stories to finalize 14 tourist sites. After field survey, each case went through a content analysis based on types and stories. Second, each case were technically analyzed and scored as sightseeing storytelling composition factors. As a result, all cases were categorized into four types. The larger its scale is, the more historical it is, the higher composition factor evaluation it received and can accommodate tourists those who have interests in both historical or religious significances. Cases that are smaller in scale and/or serving also as a church had more religious significance and attract tourists those who are interested in religious significance. In fact, these tourist sites were mostly visited by religious groups or tourists. These cases received relatively low composition factor evaluation, and turned out to have weak strength and storytelling to attract tourists. For composition factor evaluation, the result was 'curiosity>uniqueness>understandability>educational value,' and curiosity turned out to be the greatest composition factor. Based on the results, improvement direction for 'Castle of Hwajinpo' are as the following: First, 'Castle of Hwajinpo' shall organize and distribute its unique historical · religious contents. Second, since curiosity and unique symbolism are the important factors to in story composition, tourists' curiosity shall be met by linking the internal compositions and external facilities of 'Castle of Hwajinpo'.

      • KCI등재

        전류모드 CMOS 4치 논리회로를 이용한 64×64-비트 변형된 Booth 곱셈기 설계

        김정범 한국정보처리학회 2007 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.14 No.4

        This paper proposes a 64×64 Modified Booth multiplier using CMOS multi-valued logic circuits. The multiplier based on the radix-4 algorithm is designed with current mode CMOS quaternary logic circuits. Designed multiplier is reduced the transistor count by 64.4% compared with the voltage mode binary multiplier. The multiplier is designed with Samsung 0.35㎛ standard CMOS process at a 3.3V supply voltage and unit current 5㎂. The validity and effectiveness are verified through the HSPICE simulation. The voltage mode binary multiplier is achieved the occupied area of 7.5×9.4 mm2, the maximum propagation delay time of 9.8ns and the average power consumption of 45.2mW. This multiplier is achieved the maximum propagation delay time of 11.9ns and the average power consumption of 49.7mW. The designed multiplier is reduced the occupied area by 42.5% compared with the voltage mode binary multiplier. 본 논문에서는 CMOS 다치 논리회로를 이용하여 64×64 비트 Modified Booth 곱셈기를 설계하였다. 설계한 곱셈기는 Radix-4 알고리즘을 이용하여, 전류모드 CMOS 4치 논리회로로 구현하였다. 이 곱셈기는 트랜지스터 수를 기존의 전압모드 2진 논리 곱셈기에 비해 64.4% 감소하였으며, 내부 구조를 규칙적으로 배열하여 확장성을 갖도록 설계하였다. 설계한 회로는 2.5V의 공급전압과 단위전류 5㎂를 사용하여, 0.25㎛ CMOS 기술을 이용하여 구현하였으며 HSPICE를 사용하여 검증하였다. 시뮬레이션 결과, 2진 논리 곱셈기는 7.5×9.4 mm2 의 점유면적에 9.8ns의 최대 전달지연시간과 45.2mW의 평균 전력소모 특성을 갖는 반면, 설계한 곱셈기는 5.2×7.8 mm2 의 점유면적에 11.9ns의 최대 전달지연시간과 49.7mW의 평균 전력소모 특성으로 점유면적이 42.5% 감소하였다.

      • KCI등재

        저 전압 스윙 기술을 이용한 저 전력 병렬 곱셈기 설계

        김정범 한국정보처리학회 2007 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.14 No.3

        본 논문에서는 작은 점유면적과 저 전력 소모 특성을 갖도록 CPL(Complementary Pass-Transistor Logic) 논리구조의 전가산기에 저 전압 스윙 기술을 적용하여 16×16 비트 병렬 곱셈기를 설계하였다. 회로구성상 CPL 논리구조는 CMOS 논리구조에 비해 NMOS 트랜지스터만을 사용하기 때문에 작은 면적을 소비한다. 저 전압 스윙 기술은 회로에 공급되는 전압보다 낮은 전압 레벨에서 출력 동작을 하여 전력 소모를 감소시키는 기술이다. 본 논문에서는 전가산기의 출력 단에 사용되는 인버터에 저 전압 스윙 기술을 적용하여 저 전력 소모 특성을 갖는 16×16 비트 병렬 곱셈기를 설계하였다. 설계한 회로는 17.3%의 전력 소모 감소와 16.5%의 전력소모와 지연시간의 곱(PowerDelay) 감소가 이루어졌다. This paper describes a new low-swing inverter for low power consumption. To reduce a power consumption, an output voltage swing is in the range from 0 to VDD-2VTH. This can be done by the inverter structure that allow a full swing or a swing on its input terminal without leakage current. Using this low-swing voltage technology, we proposed a low-power 16×16 bit parallel multiplier. The proposed circuits are designed with Samsung 0.35㎛ standard CMOS process at a 3.3V supply voltage. The validity and effectiveness are verified through the HSPICE simulation.. Compared to the previous works, this circuit can reduce the power consumption rate of 17.3% and the power-delay product of 16.5%.

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