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Baek, Yu Mi,Yoon, Soojin,Hwang, Yeo Eun,Kim, Dong-Eun 한국조명·전기설비학회 2016 한국조명·전기설비학회 학술대회논문집 Vol. No.
<P>Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase stimulation with RNA ligands to investigate the correlation with the extent of immune response through RIG-I activation in cells. RIG-I protein favored blunt-ended, double-stranded RNA (dsRNA) ligands over sticky-ended dsRNA. Moreover, the presence of the 5'-triphosphate (5'-ppp) moiety in dsRNA further enhanced binding affinity to RIG-I. Two structural motifs in RNA, blunt ends in dsRNA and 5'-ppp, stimulated the ATP hydrolysis activity of RIG-I. These structural motifs also strongly induced IFN expression as an innate immune response in cells. Therefore, we suggest that IFN induction through RIG-I activation is mainly determined by structural motifs in dsRNA that increase its affinity for RIG-I protein and stimulate ATPase activity in RIG-I.</P>
SNS를 통해 지각된 사회적 지지가 교사의 성인애착과 직무만족도에 미치는 영향
백유미(Yu-Mi Baek) 한국콘텐츠학회 2015 한국콘텐츠학회논문지 Vol.15 No.2
본 연구는 SNS를 통해 지각된 사회적 지지가 교사들의 성인애착과 직무만족도에 미치는 영향을 살펴보고자 하였다. 이를 위해 교사들을 대상으로 설문조사를 실시하였으며, 총 103부의 응답이 최종분석에 사용되었다. 연구결과, SNS를 통해 지각된 사회적 지지가 성인애착에서는 정서적지지, 정보적지지, 도구적지지가 애착불안에 영향을 미치는 것으로 나타났으며, 애착회피에서는 정서적 지지가 통계적으로 유의한 영향을 미치는 것으로 나타났다. 또한 SNS를 통해 지각된 사회적 지지가 직무만족도에 미치는 영향에서는 정서적 지지와 정보적지지가 직무만족도에 유의한 영향을 미치는 것으로 나타났다. 결론 및 논의에서는 이러한 연구결과를 토대로 본 연구의 시사점 및 제한점을 제시하였다. This study examined the influence of social support perceived through SNS on teachers adult attachment and occupational satisfaction. In order to do so, survey was conducted on teachers and a total of 103 sets of responses were used for final analysis. As a result of the study on social support perceived through SNS, with regards to adult attachment, it was shown that emotional support, informational support, and instrumental support have influence on attachment anxiety. With regards to attachment avoidance, emotional support was shown to have statistically effective influence. In addition, with regards to influence of social support perceived through SNS on occupational satisfaction, it was shown that emotional support and informational support have effective influence on occupational satisfaction. In conclusion and discussion, the implications and limitations of this study were suggested.