Bilateral Sacrospinous Hysteropexy Versus Bilateral Sacrospinous Ligament Fixation with Vaginal Hysterectomy for Apical Uterovaginal Prolapse

Kaiyue Wang,Lijuan Shi,Zheren Huang,Yun Xu 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.3

Purpose: The aim of this retrospective study was to compare the anatomical and functional outcomes between bilateral sacrospinous hysteropexy (BSHP) and bilateral sacrospinous ligament fixation with vaginal hysterectomy (BSLF/VH) in women with apical-predominant uterovaginal prolapse. Methods: Clinical data from patients with symptomatic Pelvic Organ Prolapse-Quantification (POP-Q) stage 2 or higher uterovaginal prolapse who underwent either BSHP (48 patients) or BSLF/VH (69 patients) between January 2014 and December 2018 were reviewed retrospectively. The primary outcome was the subjective satisfaction rate evaluated by Patient Global Impression of Improvement, and the secondary outcomes included objective anatomical success rates, impact on disease-specific quality of life evaluated by the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-12, Pelvic Floor Distress Inventory-Short Form 20, and Pelvic Floor Impact Questionnaire 7, and surgical complications. Results: After a median follow-up of 35 months (range, 25–58 months), all patients in both groups demonstrated significant postoperative improvements in anatomical and functional outcomes (P<0.001). There were no significant differences in postoperative subjective and objective results, sexual satisfaction outcomes, or disease-specific quality of life between the BSHP and BSLF/VH groups, and similar incidence rates of intraoperative and postoperative complications were also recorded. Conclusions: The uterus-sparing BSHP procedure yielded noninferior anatomical and functional outcomes compared to the BSLF/VH procedure and could be adopted as an alternative to conventional hysterectomy-based native-tissue repair modalities for symptomatic apical-predominant uterovaginal prolapse.

Light-induced negative differential resistance effect in a resistive switching memory device

Xiaojun Wang,Yuanyang Wang,Ming Feng,Kaiyue Wang,Pinbo Bai,Yuming Tian 한국물리학회 2020 Current Applied Physics Vol.20 No.3

The negative differential resistance (NDR) effect was observed in a Pt/BiFeO3/TiO2/BiFeO3/Pt memory cell by using light-illumination as extra stimulation. Further, the coexistence appearances and gradually becomes obvious when the device is exposed to light-illumination, which display an excellent stability and reversibility of the coexistence of NDR and resistive switching (RS) at room temperature. Through analysis of the physical conduction mechanism, it is expected that a large number of photo-generated charge carriers are induced under light-illumination on the surface and interface of the heterojunction is responsible for the appearance of this coexistence phenomenon. Importantly, the NDR effect is strengthened by the competition transfer of charge carrier in the polarized electric field under light-illumination. This work shows that the coexistence of lightmodulated NDR and RS can deeply explore the potential applications of light-controlled multifunctional devices.

CDs/ZnO composite material with solid state fluorescence performance for quantitative determination of methyl red content and antibacterial properties

Mengqi Wang,Kaiyue Zhang,Feixiang Ji,Yurong Guo,Chao Wang,Shiping Wang,Ya Chu,Guangjiu Zhao 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.104 No.-

A water-soluble probe composite material (CDs/ZnO) was synthesized by microwave pyrolysis methodsof citric acid, urea and zinc oxide (ZnO) with aggregation-induced emission activity. We creatively realizedthe composite of CDs and nano-ZnO in the form of foam, then used as bactericide for the first timeand showed excellent antibacterial properties. Also, the composite materials overcame the problem ofaggregation-induced quenching (ACQ) and realized solid-state emission. The materials had two differentemission centers, and the two emission peaks were varied with the change of excitation wavelength. Furthermore, Methyl red (MR) showed fluorescence quenching for CDs/ZnO with obvious linear correlation,which demonstrated potential in the measurement of MR in dyeing wastewater. The CDs/ZnO weobtained perfectly inherited the advantages of CDs and nano ZnO, it has not just no cytotoxicity to cells,but also has a good killing effect on bacteria. Hence, this work shows significant adaptable fluorescencebasedprotocol with enormous potential applications in biology.

Analysis of capabilities and application characteristic of AIS

WANG shiyuan,XU kaiyu,XU zhijing,HU wenhua 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.2006 No.-

This paper compares and analyzes the capabilities and application characteristic between the shipborne AIS and ARPA Radar、AIS base station and VTS Radar, give a brief introduction of the AIS base station network’s building and application in China, and give a discussion on the information fusion and technology integrated of AIS and ARPA Radar, AIS base station network and VTS Radar.

An in vitro Actinidia Bioassay to Evaluate the Resistance to Pseudomonas syringae pv. actinidiae

Wang, Faming,Li, Jiewei,Ye, Kaiyu,Liu, Pingping,Gong, Hongjuan,Jiang, Qiaosheng,Qi, Beibei,Mo, Quanhui The Korean Society of Plant Pathology 2019 Plant Pathology Journal Vol.35 No.4

Pseudomonas syringae pv. actinidiae (Psa) is by far the most important pathogen of kiwifruit. Sustainable expansion of the kiwifruit industry requires the use of Psa-tolerant or resistant genotypes for the breeding of tolerant cultivars. However, the resistance of most existing kiwifruit cultivars and wild genotypes is poorly understood, and suitable evaluation methods of Psa resistance in Actinidia have not been established. A unique in vitro method to evaluate Psa resistance has been developed with 18 selected Actinidia genotypes. The assay involved debarking and measuring the lesions of cane pieces inoculated with the bacterium in combination with the observation of symptoms such as callus formation, sprouting of buds, and the extent to which Psa invaded xylem. Relative Psa resistance or tolerance was divided into four categories. The division results were consistent with field observations. This is the first report of an in vitro assay capable of large-scale screening of Psa-resistance in Actinidia germplasm with high accuracy and reproducibility. The assay would considerably facilitate the breeding of Psa-resistant cultivars and provide a valuable reference and inspiration for the resistance evaluation of other plants to different pathogens.

Novel Prognostic Nomograms Based on Inflammation-Related Markers for Patients with Hepatocellular Carcinoma Underwent Hepatectomy

Yifei Wang,Kaiyu Sun,Jingxian Shen,Bin Li,Ming Kuang,Qinghua Cao,Sui Peng 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4

Purpose Hepatocellular carcinoma (HCC) is an aggressive disease with high recurrence rate. However, current staging systems were lack of predictive capacity for HCC recurrence. We aimed to develop prognostic nomograms based on inflammation-related markers for HCC patients underwent hepatectomy. Materials and Methods We recruited 889 surgically treated patients from two medical centers. Independent prognostic factors were identified by cox regression analyses. Nomograms for recurrence-free survival (RFS) and overall survival (OS) were established and validated internally and externally. The performance, discrimination, and calibration of nomograms were assessed and compared with existed staging systems. Results Neutrophil to lymphocyte ratio (NLR) and gamma-glutamyl transpeptidase to platelet ratio (GPR) were the two inflammation-related factor that independently correlated with survival. NLR, GPR, international normalized ratio (INR), microvascular invasion, satellite lesions, tumor number, tumor diameter, and macrovascular invasion were used to construct nomogram for RFS while GPR, total bilirubin, INR, -fetoprotein, microvascular invasion, satellite lesions, tumor diameter, and macrovascular invasion were for OS. In the training cohort, the C-index of nomogram was 0.701 (95% confidence interval [CI], 0.669 to 0.732) for RFS and 0.761 (95% CI, 0.728 to 0.795) for OS. These results received both internal and external validation with C-index of 0.701 (95% CI, 0.647 to 0.755) and 0.707 (95% CI, 0.657 to 0.756) for RFS, and 0.706 (95% CI, 0.640 to 0.772) and 0.708 (95%CI, 0.646 to 0.771) for OS, respectively. The nomograms showed superior accuracy to conventional staging systems (p < 0.001). Conclusion The nomograms based on inflammation-related markers are of high efficacy in predicting survival of HCC patients after hepatectomy, which will be valuable in guiding postoperative interventions and follow-ups.

An in vitro Actinidia Bioassay to Evaluate the Resistance to Pseudomonas syringae pv. actinidiae

Faming Wang,Jiewei Li,Kaiyu Ye,Pingping Liu,Hongjuan Gong,Qiaosheng Jiang,Beibei Qi,Quanhui Mo 한국식물병리학회 2019 Plant Pathology Journal Vol.35 No.4

Pseudomonas syringae pv. actinidiae (Psa) is by far the most important pathogen of kiwifruit. Sustainable expansion of the kiwifruit industry requires the use of Psa-tolerant or resistant genotypes for the breeding of tolerant cultivars. However, the resistance of most existing kiwifruit cultivars and wild genotypes is poorly understood, and suitable evaluation methods of Psa resistance in Actinidia have not been established. A unique in vitro method to evaluate Psa resistance has been developed with 18 selected Actinidia genotypes. The assay involved debarking and measuring the lesions of cane pieces inoculated with the bacterium in combination with the observation of symptoms such as callus formation, sprouting of buds, and the extent to which Psa invaded xylem. Relative Psa resistance or tolerance was divided into four categories. The division results were consistent with field observations. This is the first report of an in vitro assay capable of large-scale screening of Psa-resistance in Actinidia germplasm with high accuracy and reproducibility. The assay would considerably facilitate the breeding of Psa-resistant cultivars and provide a valuable reference and inspiration for the resistance evaluation of other plants to different pathogens.

Study on the doping mechanism and electronic structure for Nb5+ doping PbWO4 crystals

Teng Chen,Kaiyu Xu,Dongli Shi,Mingjie Wang,Tingyu Liu 한국물리학회 2010 Current Applied Physics Vol.10 No.1

The existing forms of the impurity Nb5+ in the Nb5+:PbWO4 (PWO) crystals are simulated by computer technology. The possible various kinds of defects in the Nb5+:PWO crystals are also simulated. By analyzing the calculation results of defect formation energies and binding energies, the optimal substitution positions of the Nb5+ ions and the charge compensating mechanism [Nb-w+V2+ o +Nb-w] in the Nb5+:PWO crystals were obtained. The electronic structures for Nb5+:PWO were calculated with density functional theory code CASTEP. It shows that the doping of Nb5+ ions could suppress the 350 nm absorption band.

Identification and expression analysis of SQUAMOSA promoter-binding protein (SBP) genes in mungbean

Zhang Huiying,Guo Xu,Wang Zheng,Yu Zhaohang,Nie Kaiyue,Han Meng,Xu Xuexin,Zhu Hong 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.3

SQUAMOSA promoter-binding protein (SBP) genes are important transcription factors involved in plant growth and development. However, the information about mungbean VrSBP genes is limited. In this study, we identified and characterized 22 VrSBP genes in the mungbean genome. Many characteristics of VrSBP genes were analyzed, and most VrSBP genes were considered to be expressed only in the nucleus. VrSBP genes were grouped into 9 subfamilies, with the exception of the g7 and ms subfamilies which are distinctive to Poaceae species. The g3 subfamily was the largest one with 6 VrSBP members. Eight segmental events were found among VrSBP genes, and all VrSBP duplicated genes were evolved via purification selection. The gene structure of VrSBP genes in the same subfamily was similar, and the conserved motifs are different among different subfamilies of VrSBP genes. Additionally, 12 VrSBP genes were considered to be the target genes of vra-miR156a. The types and numbers of cis-acting elements in VrSBP promoters were varied and VrSBP genes showed different expression patterns in different tissues. In addition, the protein interaction network revealed that VrSBP genes were involved in many development processes. Our study has provided important information which will allow the further functional characterization of VrSBP genes.

Sclareol Protects Staphylococcus aureus-Induced Lung Cell Injury via Inhibiting Alpha-Hemolysin Expression

( Ouyang Ping ),( Sun Mao ),( He Xuewen ),( Wang Kaiyu ),( Yin Zhongqiong ),( Fu Hualin ),( Li Yinglun ),( Geng Yi ),( Shu Gang ),( He Changliang ),( Liang Xiaoxia ),( Lai Weiming ),( Li Lixia ),( Zou 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.1

Staphylococcus aureus (S. aureus) is a common gram-positive bacterium that causes serious infections in humans and animals. With the continuous emergence of methicillin-resistant S. aureus (MRSA) strains, antibiotics have limited efficacy in treating MRSA infections. Accordingly, novel agents that act on new targets are desperately needed to combat these infections. S. aureus alpha-hemolysin plays an indispensable role in its pathogenicity. In this study, we demonstrate that sclareol, a fragrant chemical compound found in clary sage, can prominently decrease alpha-hemolysin secretion in S. aureus strain USA300 at sub-inhibitory concentrations. Hemolysis assays, western-blotting, and RT-PCR were used to detect the production of alpha-hemolysin in the culture supernatant. When USA300 was co-cultured with A549 epithelial cells, sclareol could protect the A549 cells at a final concentration of 8 μg/ml. The protective capability of sclareol against the USA300-mediated injury of A549 cells was further shown by cytotoxicity assays and live/dead analysis. In conclusion, sclareol was shown to inhibit the production of S. aureus alpha-hemolysin. Sclareol has potential for development as a new agent to treat S. aureus infections.