Trajectory of Voice Rehabilitation in Ortner’s Syndrome: A Case Report

Vijay Kumar,Akriti Kumar,Anjali Sharma 한국언어재활사협회 2023 Clinical Archives of Communication Disorders Vol.8 No.2

Single-bit digital comparator circuit design using quantum-dot cellular automata nanotechnology

Vijay Kumar Sharma 한국전자통신연구원 2023 ETRI Journal Vol.45 No.3

The large amount of secondary effects in complementary metal-oxide-semiconductor technology limits its application in the ultra-nanoscale region. Circuit designers explore a new technology for the ultra-nanoscale region, which is the quantum-dot cellular automata (QCA). Low-energy dissipation, high speed, and area efficiency are the key features of the QCA technology. This research proposes a novel, low-complexity, QCA-based one-bit digital comparator circuit for the ultra-nanoscale region. The performance of the proposed comparator circuit is presented in detail in this paper and compared with that of existing designs. The proposed QCA structure for the comparator circuit only consists of 19 QCA cells with two clock phases. QCA Designer-E and QCA Pro tools are applied to estimate the total energy dissipation. The proposed comparator saves 24.00% QCA cells, 25.00% cell area, 37.50% layout cost, and 78.11% energy dissipation compared with the best reported similar design.

A novel approach for designing of variability aware low-power logic gates

Vijay Kumar Sharma 한국전자통신연구원 2022 ETRI Journal Vol.44 No.3

Metal-oxide-semiconductor field-effect transistors (MOSFETs) are continuously scaling down in the nanoscale region to improve the functionality of integrated circuits. The scaling down of MOSFET devices causes short-channel effects in the nanoscale region. In nanoscale region, leakage current components are increasing, resulting in substantial power dissipation. Very large-scale integration designers are constantly exploring different effective methods of mitigating the power dissipation. In this study, a transistor-level input-controlled stacking (ICS) approach is proposed for minimizing significant power dissipation. A low-power ICS approach is extensively discussed to verify its importance in low-power applications. Circuit reliability is monitored for process and voltage and temperature variations. The ICS approach is designed and simulated using Cadence’s tools and compared with existing low-power and high-speed techniques at a 22-nm technology node. The ICS approach decreases power dissipation by 84.95% at a cost of 5.89 times increase in propagation delay, and improves energy dissipation reliability by 82.54% compared with conventional circuit for a ring oscillator comprising 5-inverters.

Squamous Cell Carcinoma in Exstrophy of the Bladder

Pramod Kumar Sharma,Praveen Kumar Pandey,Mukesh Kumar Vijay,Malay Kumar Bera,Jitendra Pratap Singh,Kaushik Saha 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.8

Exstrophy of the bladder is a rare congenital anomaly with an incidence of about 1 per 50,000 newborns. The malignant potential of the exstrophied bladder mucosa is well known; 95% are adenocarcinomas, and 3% to 5% are squamous cell carcinomas. Most of the malignant tumors (60%) associated with an exstrophy of the bladder occur during the fourth and fifth decades of life. Of the remaining, about 20% each occur after 60 years and before 40 years. Here we present a case in which squamous cell carcinoma developed in an unrepaired exstrophy of the bladder. We present the management of the case and a brief review of the literature.

Comparison of the Oswestry Disability Index and Magnetic Resonance Imaging Findings in Lumbar Canal Stenosis: An Observational Study

Vijay G Goni,Aravind Hampannavar,Nirmal Raj Gopinathan,Paramjeet Singh,Pebam Sudesh,Rajesh Kumar Logithasan,Anurag Sharma,Shashidhar BK,Radheshyam Sament 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.1

Study Design: Cross-sectional study. Purpose: The aim of the study was to determine relationship between the degrees of radiologically demonstrated anatomical lumbar canal stenosis using magnetic resonance imaging (MRI) and its correlation with the patient’s disability level, using the Oswestry Disability Index (ODI). Overview of Literature: The relationship between the imaging studies and clinical symptoms has been uncertain in patients suffering from symptomatic lumbar canal stenosis. There is a limited number of studies which correlates the degree of stenosis with simple reproducible scoring methods. Methods: Fifty patients were selected from 350 patients who fulfilled the inclusion criteria. The patients answered the nationallanguage translated form of ODI. The ratio of disability was interpreted, and the patients were grouped accordingly. They were subjected to MRI; and the anteroposterior diameters of the lumbar intervertebral disc spaces and the thecal sac cross sectional area were measured. Comparison was performed between the subdivisions of the degree of lumbar canal stenosis, based on the following: anteroposterior diameter (three groups: normal, relative stenosis and absolute stenosis); subdivisions of the degree of central canal stenosis, based on the thecal sac cross-sectional area, measured on axial views (three groups: normal, moderately stenotic and severely stenotic); and the ODI outcome, which was also presented in 20 percentiles. Results: No significant correlation was established between the radiologically depicted anatomical lumbar stenosis and the Oswestry Disability scores. Conclusions: Magnetic resonance imaging alone should not be considered in isolation when assessing and treating patients diagnosed with lumbar canal stenosis.

Patterns of Cancer: A Study of 500 Punjabi Patients

Bal, Manjit Singh,Bodal, Vijay Kumar,Kaur, Jaspreet,Kaur, Mohanvir,Sharma, Swati Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

The State of Punjab has been in focus because of aperceived increasing rate of cancer. Both print and electronic media have created an impression that Punjab, especially the cotton belt of Malwa Region, has become a high incidence cancer region. Actually the increased number of cancer patients might be at least partly because of increasing population and heightened health awareness and reporting. The purpose of this study is to find out the pattern of cancer amongst patients registered in Mukh Mantri Punjab Cancer Rahat Kosh Scheme (MMPCRKS), under cancer registry at Rajindra Hospital Patiala from the various districts of Punjab. The study covers 500 cancer patients registered under MMPCRKS at Rajindra Hospital Patiala, for free cancer treatment. Information regarding age, gender, religion, method of diagnosis and affected sites was obtained. Results were analyzed statistically. Of the 500 patients, 65% were females and 35% were males. The most affected female age groups were 50-54 and 60-64; while males in the age groups of 65-69 and 60-64 had the highest risk. The leading cancers in females were breast followed by cervix and ovary where as in males they were were colon followed by esophagus and tongue. The commonest histological type was adenocarcinoma followed by squamous cell carcinoma. The increasing trend of cancer in Punjab is alarming. Since this study is a preliminary investigation, it could provide a leading role in prevention, treatment and future planning regarding cancer in Punjab.

Pattern of Liver Enzymes in Alcohol Dependence Syndrome Patients

( Mithileshwer Raut ),( Binod Kumar Yadav ),( Vijay Kumar Sharma ),( Eans Tara Tuladhar ),( Aseem Bhattarai ),( Bharat Jha ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Alcohol dependence syndrome (ADS) has become a global public health challenge because of its high prevalence and the concomitant increase in risk of liver disease, cardiovascular disease and premature death. Influence of alcohol use on liver metabolism is well recognized. This study was aimed at examining the association of liver enzymes like γ-glutamyltransferase (GGT) and aminotransferase, with alcohol dependence syndrome patients. Methods: This cross-sectional study was conducted in Tribhuvan University Teaching Hospital. ADS patients were screened by the consultant psychiatrist using the Alcohol Use Disorder Identification Test (AUDIT) questionnaire. A total of 89 patients scored positive on the AUDIT as having alcohol-related problems and were included in the study. Blood Pressure and other anthropometric parameters were measured while blood samples were analyzed for liver enzymes and serum protein. Results: Mean age of cases and controls was 35.42 ± 5.6 & 34.53 ± 3.5 years respectively. The mean values of Gamma GT, SGOT and SGPT were largely elevated in cases as compared to the controls with a statically significance (P<0.001). Among the ADS cases serum GGT level was elevated in 97% patients. The SGOT/SGPT ratio was also significantly higher in cases (2.02 ± 0.39) and control (1.45±0.62). It was found that 15.1 % cases had low serum protein level and 32.9% cases were low serum albumin level. Albumin to globulin ratio was also significantly decreased in cases (1.16 ±0.29). Conclusions: These findings support the hypothesis that, alcohol may affect the pattern of liver enzymes and also damage the liver cells. Decrease in serum albumin and elevation of SGOT to SGPT ratio more than two is suggestive of development of liver cirrhosis in alcohol dependence patients.

Effect of Mandibular Advancement Splint on Obstructive Sleep Apnea with Insulin Resistant Diabetes

Ashutosh Gupta,Arvind Tripathi,Praveen Rai,Piyush Sharma,Vijay Yadav,Dewanshu Kumar 대한수면연구학회 2020 Journal of sleep medicine Vol.17 No.1

Objectives: Obstructive Sleep apnea (OSA) is characterized by complete or partial obstruction of upper airflow despite the effort to breathe, leading to hypoxemia and hypercapnia. The resultant apnea causes sleep fragmentation, which in turn increases sympathetic activity, decreases insulin sensitivity and glucose uptake, and stimulates hepatic gluconeogenesis that ultimately leads to type 2 diabetes. Most studies exploring the effect of continuous positive airway pressure on insulin sensitivity have showed a positive effect. However, there is no evidence on the effect of mandibular advancement device on insulin resistance (IR). This study was aimed to evaluate the effect of mandibular advancement splint (MAS) on IR in patients with OSA. Methods: The present study was conducted at Department of Prosthodontics, Dental College Azamgarh, from June 2015 to July 2017. Sixty eight dentulous patients with type 2 diabetes and mild to moderate OSA and with stable diabetic regimen were included in the study. A MAS was fabricated and fixed at 70% of the maximum mandibular protrusion recorded. Patients that were comfortable with MAS after one month were assessed for apnea-hypopnea index, mean oxygen saturation, and IR at baseline, 6 months, and 1 year after wearing MAS. Results: An improvement in insulin sensitivity was observed at 6 months for mild OSA patients (p=0.001). For moderate OSA patients, no significant improvement was observed following MAS use (p>0.05). Conclusions: The finding suggested that MAS is effective in improving IR in mild OSA patients.

Investigation of transport of radionuclide in a thermal stratification test facility using radiotracer technique

Harish Jagat Pant,Sunil Goswami,Sunil B. Chafle,Vijay Kumar Sharma,Vimal Kotak,Vikram Shukla,Amitanshu Mishra,Nilesh C. Gohel,Sujay Bhattacharya 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.4

A radiotracer investigation was carried out in a Thermal Stratification Test Facility (TSTF) with objectivesof investigating the dispersion and diffusion of radionuclide and effectiveness of the thermocline tominimize the radionuclide content in the hot water layer. Technetium-99m (99mTc) as sodium pertechnetate was used as a radiotracer in the investigation. Qualitative analysis showed that a thermoclineis formed within the TSTF and is effective in preventing the transport of radionuclide from bottomsection to the top section of the facility. It was found that the radiotracer injected at the bottom of thepool took about 17.4 h to disperse from bottom to the top of the facility. The results of the investigationhelped in understanding the effectiveness of hot water layer and thus to minimize the pool top radiationlevels.

Design and Autonomous Control of the Active Adaptive Suspension System of Rudra - Mars Rover

Karan Vaish,Shah Mihir Rajesh,Karthikeyan Pasupatheeswaran,Manoj Kumar Sharma,Vijay B. Semwal 보안공학연구지원센터 2014 International Journal of Hybrid Information Techno Vol.7 No.3