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      • KCI등재후보

        Pediatric Femoral Neck Fractures: Our 10 Years of Experience

        Kamal Bali,Pebam Sudesh,Sandeep Patel,Vishal Kumar,Uttam Saini,M. S. Dhillon 대한정형외과학회 2011 Clinics in Orthopedic Surgery Vol.3 No.4

        Background: Femoral neck fractures are rare injuries in children, but the high incidence of long term complications make it animportant clinical entity. The aim of this retrospective study was to analyze the clinical outcomes of pediatric femur neck fracturesthat we managed over a 10 year period. Methods: The study included 36 children (20 boys and 16 girls) who sustained femoral neck fractures and completed a minimumfollow-up of one year. The children were treated either conservatively, or by open reduction and internal fi xation (ORIF), or closedreduction and internal fi xation (CRIF). The outcomes were analyzed using Ratliff criteria and a detailed record of complicationswas kept for all patients. Results: The mean age of included patients was 10 years (range, 3 to 16 years) and the average follow-up was 3.2 years (range,1.1 to 8.5 years). Based on Delbet’s classifi cation system, there were 0 type I (transepiphyseal), 16 type II, 11 type III, and 9 type IVfractures. There were 8 undisplaced fractures, 4 of which later displaced after being managed initially in a hip spica. A satisfactoryoutcome was obtained in 27 (75%) children. Avascular necrosis (AVN) was the most common complication. It was seen in7 of our patients, all of whom had an unsatisfactory outcome. Other complications included three cases each of coxa vara, nonunion,and arthritic changes; and one case each of infection, primary screw perforation of head, and premature epiphyseal closure. Complications were lowest in the group treated by ORIF. Only 2 patients managed exclusively by conservative treatment ultimatelyachieved a satisfactory outcome. Conclusions: We believe that internal fi xation of pediatric femoral neck fractures is preferred whenever feasible because conservativetreatment carries a high risk of failure of reduction. Aggressive operative treatments aimed at anatomical reduction shouldbe the goal and there should be no hesitation in choosing ORIF over CRIF. Outcome of patients is infl uenced primarily by developmentof AVN which occurs as an independent entity without much relation to the mode of treatment carried out.

      • KCI등재

        Safety Profile, Feasibility and Early Clinical Outcome of Cotransplantation of Olfactory Mucosa and Bone Marrow Stem Cells in Chronic Spinal Cord Injury Patients

        Vijay G Goni,Rajesh Chhabra,Ashok Gupta,Neelam Marwaha,Mandeep S Dhillon,Sudesh Pebam,Nirmal Raj Gopinathan,Shashidhar Bangalore Kantharajanna 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.4

        Study Design: Prospective case series. Purpose: To study the safety and feasibility of cotransplantation of bone marrow stem cells and autologous olfactory mucosa in chronic spinal cord injury. Overview of Literature: Stem cell therapies are a novel method in the attempt to restitute heavily damaged tissues. We discuss our experience with this modality in postspinal cord injury paraplegics. Methods: The study includes 9 dorsal spine injury patients with American Spinal Injury Association (ASIA) Impairment Scale (AIS) A neurological impairment who underwent de-tethering of the spinal cord followed by cotransplantation with bone marrow stem cells and an olfactory mucosal graft. Participants were evaluated at the baseline and at 6 monthly intervals. Safety and tolerability were evaluated through the monitoring for adverse events and magnetic resonance imaging evaluation. Efficacy assessment was done through neurological and functional outcome measures. Results: Surgery was tolerated well by all participants. No significant difference in the ASIA score was observed, although differences in the Functional Independence Measure and Modified Ashworth Scale were statistically significant. No significant complication was observed in any of our patients, except for neurogenic pain in one participant. The follow-up magnetic resonance imaging evaluation revealed an increase in the length of myelomalacia in seven participants. Conclusions: The cotransplantation of bone marrow stem cells and olfactory mucosa is a safe, feasible and viable procedure in AIS A participants with thoracic level injuries, as assessed at the 24-month follow-up. No efficacy could be demonstrated. For application, further large-scale multicenter studies are needed.

      • KCI등재

        Comparison of the Oswestry Disability Index and Magnetic Resonance Imaging Findings in Lumbar Canal Stenosis: An Observational Study

        Vijay G Goni,Aravind Hampannavar,Nirmal Raj Gopinathan,Paramjeet Singh,Pebam Sudesh,Rajesh Kumar Logithasan,Anurag Sharma,Shashidhar BK,Radheshyam Sament 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.1

        Study Design: Cross-sectional study. Purpose: The aim of the study was to determine relationship between the degrees of radiologically demonstrated anatomical lumbar canal stenosis using magnetic resonance imaging (MRI) and its correlation with the patient’s disability level, using the Oswestry Disability Index (ODI). Overview of Literature: The relationship between the imaging studies and clinical symptoms has been uncertain in patients suffering from symptomatic lumbar canal stenosis. There is a limited number of studies which correlates the degree of stenosis with simple reproducible scoring methods. Methods: Fifty patients were selected from 350 patients who fulfilled the inclusion criteria. The patients answered the nationallanguage translated form of ODI. The ratio of disability was interpreted, and the patients were grouped accordingly. They were subjected to MRI; and the anteroposterior diameters of the lumbar intervertebral disc spaces and the thecal sac cross sectional area were measured. Comparison was performed between the subdivisions of the degree of lumbar canal stenosis, based on the following: anteroposterior diameter (three groups: normal, relative stenosis and absolute stenosis); subdivisions of the degree of central canal stenosis, based on the thecal sac cross-sectional area, measured on axial views (three groups: normal, moderately stenotic and severely stenotic); and the ODI outcome, which was also presented in 20 percentiles. Results: No significant correlation was established between the radiologically depicted anatomical lumbar stenosis and the Oswestry Disability scores. Conclusions: Magnetic resonance imaging alone should not be considered in isolation when assessing and treating patients diagnosed with lumbar canal stenosis.

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