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사철나무 알칼로이드, Euojaponine의 NMR스펙트럼의 분석
柳載夏,李沼映,李叔淵,韓秉勳 숙명여자대학교 약학연구소 1994 약학논문집-숙명여자대학교 Vol.10 No.-
The strutures of euojaponines, alkaloidal components from Euonymus japonica are composed of β-agarofuran type sesquiterpene and pyridic dibasic acid, and they are linked via cyclodiester bonds. The structures of these compounds were elucidated by the application of various two dimensional NMR methods. From the results of complete interpretation of NMR spectra, several correlating aspects between structure and spectral pattern of sesquiterpene moiety were found, which can be utilized for the structural determination of the same family compounds.
성교육 프로그램이 청소년 성의식과 성태도에 미치는 효과 : 정신병원 청소년병동 입원환자를 대상으로
류미숙 외 국립서울병원 정신보건교육·연구센터 2008 정신건강정책포럼 Vol.2 No.1
• Purpose : Sexual Education Program on adolescence sexual health has been developed by researchers in accordance with the national education courses. However, there have been not the study which found the effects of this program on sexual consciousness and sexual attitudes of psychiatric in-patient adolescents. • Method : Non-equivalent control group pretest-posttest design was used. Twenty six adolescents participated in an experiment. National Seoul mental hospital in-patients were selected for a convenience sampling method and have been taught the sexual education program during six weeks. • Result : There were significant differences in the sexual consciousness(t:-2.835. p:0.009) and sexual attitudes(t:-1.826. p:0.008) after the sexual education program • Conclusion : Since the sexual education program can affirmative influence on the sexual consciousness and sexual attitudes of the adolescence, it is recommendable to perform the sexual education program suitable for every stage of growth and development.
고학력 여성인력 개발 및 활용을 위한 평생학습 지원체제 연구
박승호,유숙영 서울여자대학교 여성연구소 2006 여성연구논총 Vol.21 No.-
One of the most serious problems of our society is the very low rate of high educated or high skilled women's social participation rate, and limited opportunity in higher value-added businesses for women. Efforts to make human resources of high educated women are so urgent for entering top 10 countries with competitive human power that Korean government enacted laws promoting development and use of them. These steps can be proper only when based on understanding of their real situation and their needs. With study on relative documents and survey on high educated women, we made some suggestions for a lifelong learning support system promoting development and use of high educated woman resources. First, the system should be based on woman's needs driven from their places in their life cycles. Second, the system sould be various on the learning style and characteristics of women. Third, collaborative relations between lifelong learning system and the local community need to be built. Forth, woman lerners should be encouraged by emotional supports from other family members and shared household chores. To develop and use high educated woman resources, more educational facilities in the community should be used for women to learn at any time and in any place. Second, more active supports should be offered through close cooperation among lifelong educational institutes. Woman learners can manage their course of career development with the database on their learning. Third, by database on high educated women, they should be given more opportunities to get appropriated places for their abilities. Forth, higher value-added business for high educated women should be developed. Finally, more opportunities of grant-type lifelong education should be offered to them.
Efficient Unlinkable Secret Handshakes for Anonymous Communications
Eun-Kyung Ryu1,Kee-Young Yoo,Keum-Sook Ha 보안공학연구지원센터(JSE) 2010 보안공학연구논문지 Vol.7 No.6
The technique of secret handshake is used as a fundamental building block for anonymous peer-to-peer communications over untrusted networks. However, the fact that most existing schemes fail to meet unlinkability causes the use of schemes to limit for practical use. In this paper, we provide new constructions for unlinkable secret handshake, allowing arbitrary two communication parties with the same role in either one single group or multiple groups to privately authenticate each other. Compared to previous works, our techniques have much better performance in terms of both computational and communication cost, while they obtain good security results.
대유행 인플루엔자(H1N1 2009) 급성호흡곤란증후군에 대한 체외막 산소화 장치의 조기적용 1예
이경학,이길수,오원섭,유숙원,천성빈,이승준 대한감염학회 2010 감염과 화학요법 Vol.42 No.2
Despite advanced technologies in intensive care, pandemic influenza (H1N1 2009) can rapidly progress to acute respiratory distress syndrome (ARDS) and cause death in a small subset of patients. Extracorporeal membrane oxygenation (ECMO) is expected to provide adequate gas exchange, to reduce ventilator-induced lung injury and, eventually, to improve outcome in these patients. A previously healthy, young female received mechanically ventilatory support because of rapidly progressive respiratory failure caused by 2009 H1N1 influenza. As she failed to respond to high ventilatory support, ECMO was instituted at 6 hours after admission. We describe detailed course of case and literature review on ECMO, helping physicians make a decision to initiate ECMO in patients with influenza-related ARDS.
Ryu, Geon-Seek,Park, Soo-Hee,Kim, Eun-Sook,Choi, Byoung-Wook,Ryu, Shi-Yong,Lee, Bong-Ho The Pharmaceutical Society of Korea 2003 Archives of Pharmacal Research Vol.26 No.10
Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea. Compounds 1 and 2 were identified as (5E,10Z)-6, 10, 14-trimethylpentadeca-5, 10-dien-2, 12-dione and (5E,9E,13E)-6, 10,4-trimethylpentadeca-5,9,13-trien-2,12-dione, respectively, by comparison with the literature data. Compounds 1 and 2 showed moderate acetylcholinesterase and butyrylcholinesterase inhibitory activities with $IC_{50}$ values of 65.0∼48.0 and 34.0∼23.0 $\muM$, respectively.
Ryu, Jae Sook,Min, Duk Young,Kim, Myeong Cheol,Kim, Nam Sik,Shin, Myeong Heon 한국미생물 · 생명공학회 2001 Journal of microbiology and biotechnology Vol.11 No.1
The in vitro activity of 2,2'-dipyridyl, an ironchelator, against clinical isolates of Trichomonas vaginalis, Candida albicans, and Gardnerella vaginalis was evaluated and compared with those of four other vaginal suppositories, ornidazole, clotrimazole, povidone-iodine, and Cenacert^ (Methylbenzethonium Chloride mixed with 9-aminoacrydine undecylenate and hydrochloric acid N-myristyl-3-hydroxy butyl amine). The 2,2'-dipyridyl killed T. vaginalis and G. vaginalis at concentrations of 410㎍/ml and 205㎍/ml, respectively, however, this agent was less active against C. albicans (80% of which was inhibited at 410㎍/ml). The inhibition of these three pathogens by 2,2'-dipyridyl was similar to clotrimazole. In addition, the effect of 2,2'-dipyridyl on the ultrastructure of T. vaginalis, C. albicans, and G. vaginalis was examined. Transmission electron microscopy indicated that 2,2'-dipyridyl induced modifications of the cellular contents and cell envelope concomitant with the degradation of the three pathogens. These results suggest that 2,2'-dipyridyl has an inhibitory effect on C. albicans and G. vaginalis, as well as T. vaginalis.
Successful reconstruction of a nasal defect after Mohs surgery with a double-island pedicle flap
( Sook In Ryu ),( Jae Yeong Jeong ),( Ko Eun Kim ),( Bo Young Kim ),( Il-hwan Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
The nasal ala-perialar area is located centrally on a face. The defect in the area involves the nasofacial angle, nasal sidewall, nasolabial fold and malar area. Therefore, repairing defects in the area is challenging and facial subunit concept should be considered. We report a successfully reconstructed case of a 2.1x1.4 cm nasal sidewall defect. A 47-year-old female came to our clinic with a black macule on the right nasal sidewall. She had laser therapy on the lesion multiple times, but the lesion has recurred. She had biopsy at a local clinic and diagnosed as BCC. We examined the lesion with dermoscopy and found arborizing vessels and short fine telangiectasia. Additionally, there were whitish scar-like depigmented structureless area and pigmentation along the whitish radiation. The tumor was removed after the 4th stage of Mohs surgery. We designed a double-island pedicle flap to avoid alar distortion with minimal scar. The defect was successfully repaired without functional abnormality and cosmetic disfigurement. In this case, the lesion was misdiagnosed as a benign nevus and treated with ablative laser. We learned that dermoscopic analysis before laser therapy of pigmented lesions is important to avoid misdiagnosis. The laser therapy made the lesion subclinically infiltrate deeper and wider which increased the stage of Mohs surgery. Herein we report this case to emphasize the importance of diagnostic procedure in pigmented lesions