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      • Kinetic favorability of Ru-doped LiNi<sub>0.5</sub>Mn<sub>1.5</sub>O<sub>4</sub> for high-power lithium-ion batteries

        Chae, Ji Su,Jo, Mi Ru,Kim, Yong-Il,Han, Dong-Wook,Park, Sun-Min,Kang, Yong-Mook,Roh, Kwang Chul Elsevier 2015 Journal of industrial and engineering chemistry Vol.21 No.-

        <P><B>Abstract</B></P> <P>Pristine and Ru-doped LiNi<SUB>0.5</SUB>Mn<SUB>1.5</SUB>O<SUB>4</SUB> samples were synthesized using a simple carbon combustion method. Crystallographic analyses combining X-ray diffraction and Rietveld refinement confirmed that formation of the Li<SUB> <I>x</I> </SUB>Ni<SUB>1−<I>x</I> </SUB>O-like impurity phase is prevented and that the lattice parameter increases as a result of Ru doping. Furthermore, its structure is partially changed to the more disordered spinel phase (<I>Fd</I>3<I>m</I>). Both this structural change and the disappearance of the impurity phase greatly enhance the rate capability and cyclic retention of LiNi<SUB>0.5</SUB>Mn<SUB>1.5</SUB>O<SUB>4</SUB>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> LiNi<SUB>0.5</SUB>Mn<SUB>1.5</SUB>O<SUB>4</SUB> is doped with Ru<SUP>4+</SUP> to reduce the degree of cation ordering. </LI> <LI> Its structure is partially changed to more disordered spinel (<I>Fd</I>3<I>m</I>). </LI> <LI> This structural change is accompanied with the disappearance of impurity phase. </LI> <LI> These changes greatly enhance rate capability and cyclic retention of LiNi<SUB>0.5</SUB>Mn<SUB>1.5</SUB>O<SUB>4</SUB>. </LI> </UL> </P>

      • KCI등재

        Bandwidth Enhancement of Circularly Polarized Dielectric Resonator Antenna

        Ru-Ying Sun 한국전자통신연구원 2015 ETRI Journal Vol.37 No.1

        Axial-ratio (AR) bandwidth enhancement is achieved for a circularly polarized (CP) cylindrical dielectric resonator antenna (DRA) using a wideband hybrid coupler (WHC) combined with dual probe feed. The presented WHC, comprised of a Wilkinson power divider and a wideband 90° shifter, delivers good characteristics in terms of 3 dB power splitting and consistent 90° (5°) phase shifting over a wide bandwidth. In turn, the proposed CP DRA, for the employment of the WHC, in place of conventional designs, provides a significant enhancement on AR bandwidth and impedance matching. The antenna prototype with the WHC exhibits a 3 dB AR bandwidth of 48.66%, an impedance bandwidth of 52.5% for voltage standing wave ratio (VSWR) ≤ 2, and a bandwidth of 44.66% for a gain of no less than 3 dBi. Experiments demonstrate that the proposed WHC is suitable for broadband CP DRA design.

      • KCI등재

        Leukotriene B4 Regulates Proliferation and Differentiation of Cultured Rat Myoblasts via the BLT1 Pathway

        Ru Sun,Xueqing Ba,Lingling Cui,Yan Xue,Xianlu Zeng 한국분자세포생물학회 2009 Molecules and cells Vol.27 No.4

        Skeletal muscle regeneration is a highly orchestrated process initiated by activation of adult muscle satellite cells. Upon muscle injury, the inflammatory process is always accompanied by muscle regeneration. Leukotriene B4 is one of the essential inflammatory mediators. We isolated and cultured primary satellite cells. RT-PCR showed that myoblasts expressed mRNA for LTB4 receptors BLT1 and BLT2, and LTB4 promoted myoblast proliferation and fusion. Quantitative real-time PCR and immunoblotting showed that LTB4 treatment expedited the expression process of differentiation markers MyoD and M-cadherin. U-75302, a specific BLT1 inhibitor, but not LY2552833, a specific BLT2 inhibitor, blocked proliferation and differentiation of myoblasts induced by LTB4, which implies the involvement of the BLT1 pathway. Overall, the data suggest that LTB4 contributes to muscle regeneration by accelerating proliferation and differentiation of satellite cells.

      • KCI등재

        Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure

        Sun Ru,Gu Qun,Zhang Xufeng,Zeng Ruiqi,Chen Dan,Yao Jingjing,Min Jingjing 한국독성학회 2024 Toxicological Research Vol.40 No.2

        Chronic renal failure (CRF) resulting in vascular calcification, which does damage to blood vessels and endothelium, is an independent risk factor for stroke. It has been reported that cilostazol has a protective effect on the focal cerebral ischemic infarct. However, its impact on vascular injury in CRF combined stroke and its molecular protection mechanism have not been investigated. In this study, we carried out the effect of cilostazol on CRF combined stroke rats, and the results confirmed that it improved the neurobehavior, renal function as well as pathologic changes in both the kidney and brain. In addition, the inflammation and oxidative stress factors in the kidney and brain were suppressed. Moreover, the rates of brain edema and infarction were decreased. The injured brain-blood barrier (BBB) was recovered with less Evans blue extravasation and more expressions of zonula occludens-1(ZO-1) and occludin. More cerebral blood flow (CBF) in the ipsilateral hemisphere and more expression of CD31 and vascular endothelial growth factor (VEGF) in brain and kidney were found in the cilostazol group. Furthermore, cell apoptosis and cell autophagy became less, on the contrary, proteins of vascular endothelial growth factor receptor 2 (VEGFR2) after the cilostazol treatment were increased. More importantly, this protective effect is related to the pathway of Janus Kinase (JAK)/signal transducer and activator of transcription 3 (STAT3), mammalian target of rapamycin (mTOR), and the hypoxia inducible factor-1α (HIF-1α). In conclusion, our results confirmed that cilostazol exerted a protective effect on the brain and kidney function, specifically in vascular injury, oxidative stress, cell apoptosis, cell autophagy, and inflammation response in CRF combined with stroke rats which were related to the upregulation of JAK/STAT3/mTOR signal pathway.

      • KCI등재

        Morphology, Thermal and Crystallization Properties of Polyamide-6/Boron Nitride (BN) Thermal Conductive Composites

        Ru Xia,Manman Sun,Bin Yang,Jiasheng Qian,Peng Chen,Ming Cao,JIBIN MIAO,LIFEN SU 한국고분자학회 2018 폴리머 Vol.42 No.2

        A series of the thermal conductive polyamide-6 (PA6) composites filled with boron nitride (BN) were prepared by two methods, including melting method (MM) and solution method (SM). The thermal conductivity, morphology, crystallization behavior, thermal stability, and rheological properties of PA6 composites were investigated. The results showed that the thermal conductivity of two methods increased with increase in the filler content, the thermal conductivity of PA6/BN composites containing 40 wt% BN prepared by melting method was up to 1.02W·m-1·K-1, while the thermal conductivity of PA6/BN composites prepared by solution method was up to 1.44 W·m-1·K-1 at the same filler content.

      • SCISCIESCOPUS

        Direct Chemical Vapor Deposition-Derived Graphene Glasses Targeting Wide Ranged Applications

        Sun, Jingyu,Chen, Yubin,Priydarshi, Manish Kr.,Chen, Zhang,Bachmatiuk, Alicja,Zou, Zhiyu,Chen, Zhaolong,Song, Xiuju,Gao, Yanfeng,Rü,mmeli, Mark H.,Zhang, Yanfeng,Liu, Zhongfan American Chemical Society 2015 NANO LETTERS Vol.15 No.9

        <P>Direct growth of graphene on traditional glasses is of great importance for various daily life applications. We report herein the catalyst-free atmospheric-pressure chemical vapor deposition approach to directly synthesizing large-area, uniform graphene films on solid glasses. The optical transparency and sheet resistance of such kinds of graphene glasses can be readily adjusted together with the experimentally tunable layer thickness of graphene. More significantly, these graphene glasses find a broad range of real applications by enabling the low-cost construction of heating devices, transparent electrodes, photocatalytic plates, and smart windows. With a practical scalability, the present work will stimulate various applications of transparent, electrically and thermally conductive graphene glasses in real-life scenarios.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2015/nalefd.2015.15.issue-9/acs.nanolett.5b01936/production/images/medium/nl-2015-019367_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl5b01936'>ACS Electronic Supporting Info</A></P>

      • SCIESCOPUSKCI등재

        Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway

        Jinghui Sun,Ru Wang,Tiantian Chao,Jun Peng,Chenglong Wang,Keji Chen The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

        Background: Myocardial fibrosis (MF) is an advanced pathological manifestation of many cardiovascular diseases, which can induce heart failure and malignant arrhythmias. However, the current treatment of MF lacks specific drugs. Ginsenoside Re has anti-MF effect in rat, but its mechanism is still not clear. Therefore, we investigated the anti-MF effect of ginsenoside Re by constructing mouse acute myocardial infarction (AMI) model and AngII induced cardiac fibroblasts (CFs) model. Methods: The anti-MF effect of miR-489 was investigated by transfection of miR-489 mimic and inhibitor in CFs. Effect of ginsenoside Re on MF and its related mechanisms were investigated by ultrasonographic, ELISA, histopathologic staining, transwell test, immunofluorescence, Western blot and qPCR in the mouse model of AMI and the AngII-induced CFs model. Results: MiR-489 decreased the expression of α-SMA, collagenI, collagen III and myd88, and inhibited the phosphorylation of NF-κB p65 in normal CFs and CFs treated with AngII. Ginsenoside Re could improve cardiac function, inhibit collagen deposition and CFs migration, promote the transcription of miR-489, and reduce the expression of myd88 and the phosphorylation of NF-κB p65. Conclusion: MiR-489 can effectively inhibit the pathological process of MF, and the mechanism is at least partly related to the regulation of myd88/NF-κB pathway. Ginsenoside Re can ameliorate AMI and AngII induced MF, and the mechanism is at least partially related to the regulation of miR-489/myd88/NF-κB signaling pathway. Therefore, miR-489 may be a potential target of anti-MF and ginsenoside Re may be an effective drug for the treatment of MF.

      • KCI등재

        Economic performance of cable supported bridges

        Bin Sun,Li-wen Zhang,Yidong Qin,Ru-cheng Xiao 국제구조공학회 2016 Structural Engineering and Mechanics, An Int'l Jou Vol.59 No.4

        A new cable-supported bridge model consisting of suspension parts, self-anchored cable-stayed parts and earth-anchored cable-stayed parts is presented. The new bridge model can be used for suspension bridges, cable-stayed bridges, cable-stayed suspension bridges, and partially earth-anchored cable-stayed bridges by varying parameters. Based on the assumption that each structural member is in either an axial compressive or tensile state, and the stress in each member is equal to the allowable stress of the material, the material quantity for each component is calculated. By introducing the unit cost of each type of material, the estimation formula for the cost of the new bridge model is developed. Numerical examples show that the results from the estimation formula agree well with that from the real projects. The span limit of cable supported bridge depends on the span-to-height ratio and the density-to-strength ratio of cables. Finally, a parametric study is illustrated aiming at the relations between three key geometrical parameters and the cost of the bridge model. The optimization of the new bridge model indicates that the self-anchored cable-stayed part is always the dominant part with the consideration of either the lowest total cost or the lowest unit cost. It is advisable to combine all three mentioned structural parts in super long span cable supported bridges to achieve the most excellent economic performance.

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