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실측과 CFD을 통한 해인사 경내 및 판전에 대한 기류분포 특성의 조사
임종연(Lim Jong-Yeonn),송두삼(Song Doo-Sam),이상해(Lee Sang-Hae) 한국건축친환경설비학회 2007 한국건축친환경설비학회 논문집 Vol.1 No.3
Hae-In temple is located in Gaya Mountains, Hapcheon-gun, Korea and a thousand years old monastery. Tripitaka Koreana has been preserved during 750 years as good condition in Hae-In temple. The preservation technology is summarized as the passive design methods harmonized with the nature perfectly. Haein temple have dealt with a flow fields in the storage hall. In this study, an indoor and outdoor flow fields in the precincts of Haein temple were analysed with field measurement and numerical simulation. On the basis of the field measurement results, the restoration cases such as rearrangement of Tripitaka Koreana and relocation of the rear fence of Biro-Jean were analyzed with CFD.
Lee, Sang Youp,Kim, Sang Hae 한국유전학회 2003 Genes & Genomics Vol.25 No.4
The genetic variation and the molecular discrimination of Scapharca species in Korea were investigated through the mitochondrial DNA sequence analyses. A partial portion (646 bp) of the mitochondrial cytochrome c oxidase subunit I gene (COI) for these species was analyzed by DNA sequencing and restriction fragment length polymorphism (RFLP). A sequence comparison and phylogenetic analysis showed both S. broughtonii and S. satowi formed a sister group, with then S. subcrenata clustered with the clade. It was assumed that all Scapharca species could form a monophyletic clade, with high bootstrap support (99%). In order to effectively discriminate the morphologically hard to classified spats, a PCR-RFLP diagnostic marker was developed with two restriction enzyme (HaeⅢ and HinfI) digestions. Digestion of the 646-bp fragments of the COI gene amplified from each species with HaeⅢ produced no fragment in the S. broughtonii, and two fragments, but of different sizes in S. satowi and S. subcrenata. In the HinfI digestion, two distinct fragments were produced in S. broughtonii and S. subcrenata, but no fragment in S. satowi. Twenty individuals from each population were digested by these two restriction enzymes, but no individual variations occurred.
노인종합복지관 프로그램 이용 만족이 노인의 우울정서와 안녕감에 미치는 영향
이의용(Lee Eui-Yong),변상해(Byun, Sang-Hae) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.4
본 연구의 목적은 노인의 여가활동 중 노인종합복지관 프로그램 활용 및 이용 만족도에 따른 우울정서와 안녕감의 관계를 규명하는 것이다.연구를 위해 서울에 소재하고 있는 노인종합복지관 2곳을 선택하여 65세 이상 되는 노인 128명을 대상으로 설문을 배포하고 수집하여 분석하였다.자료분석은 SPSSv.21을 활용하였다.연구 결과,첫째,복지관 프로그램 중 가장 만족도가 높은 것은 노래교실이었다.이용 이유로는 친구를 만나기 위해서가 많았고,주요활동 분야는 취미활동이었 다.둘째,일반적 특성에 따른 우울정서의 차이는 연령과 학력에서 유의한 차이가 나타났고,심리적 안녕감은 학력수준에 따라서 유의한 차이가 나타났다.셋째,프로그램 이용 만족도는 우울정서와 안녕감에 유의한 영향을 미치고 있는 것으로 나타났다.넷째,프로그램 만족도와 우울정서의 사이에서 심리적 안녕감의 매개효과는 나타나지 않았다. The purpose of this study is to investigate how leisure programs are utilized by senior welfare centers, and analyze the relationship between the degree of satisfaction and the resulting effect on the depressive emotions and psychological well-being of program participants. To that end, a survey was made on 128 persons aged 65 or over who were participating in leisure programs at 2 senior centers located in Seoul. The collected data were analyzed using SPSS Ver. 21. The findings were as follows: First, the most satisfactory program was Sing-Along program, while the reason for using senior welfare centers was for meeting friends and the most favorite program was hobby classes; Second, significant differences were found in depressive emotions according to age and educational background and in psychological well-being according to educational background. Third, the degree of satisfaction in programs had a meaningful relationship with depressive emotion and well-being; Fourth, there was no mediating effect of psychological well-being between the degree of program satisfaction and depressive emotion.
Lee, Hae-June,Lee, Jae-Seon,Pack, Jeong-Ki,Choi, Hyung-Do,Kim, Nam,Kim, Sung-Ho,Lee, Yun-Sil Academic Press 2009 Radiation research Vol.172 No.5
<P>Concern about the possible adverse effects of radiofrequency (RF)-field exposure on public health has increased because of the extensive use of wireless mobile phones and other telecommunication devices in daily life. The murine fetus is a very sensitive indicator of the effects of stress or stimuli in the environment. Therefore, we investigated the teratogenic effects of multi-signal radiofrequency electromagnetic fields (RF EMFs) on mouse fetuses. Pregnant mice were simultaneously exposed to two types of RF signals, single code division multiple access (CDMA) and wideband code division multiple access (WCDMA). Mice received two 45-min RF-field exposures, separated by a 15-min interval, daily throughout the entire gestation period. The whole-body average specific absorption rate (SAR) of CDMA or WCDMA was 2.0 W/kg. The animals were killed humanely on the 18th day of gestation and fetuses were examined for mortality, growth retardation, changes in head size and other morphological abnormalities. From the results, we report for the first time that simultaneous experimental exposure to CDMA and WCDMA RF EMFs did not cause any observable adverse effects on mouse fetuses.</P>
Modification of gamma-radiation response in mice by green tea polyphenols
Lee, Hae June,Kim, Joong Sun,Moon, Changjong,Kim, Jong Choon,Lee, Yun Sil,Jang, Jong Sik,Jo, Sung Kee,Kim, Sung Ho John Wiley Sons, Ltd. 2008 Phytotherapy research Vol.22 No.10
<P>In this study we evaluated the effect of water extracts of green tea (GT) and mixtures of green tea polyphenols (GTPs), epigallocatechin gallate (EGCG), epicatechin gallate (ECG), epigallocatechin (EGC) and epicatechin (EC) on jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells of mice irradiated with gamma-ray. The radioprotective effect of green tea was compared with the effect of diethyldithiocarbamate (DDC). Jejunal crypts were protected by pretreatment of GT and ECG. Administration of GT, GTPs and EC prior to irradiation resulted in an increase in the formation of endogenous spleen colonies. The frequency of apoptosis in crypt cells was also reduced by pretreatment of GT, GTPs, EGCG, ECG and EGC. In the experiment on the effect of catechins, the effects were partly contradicted in irradiated mice. The rank order of activity was ECG > EGC > EGCG > EC on intestinal crypt survival assay, EC > EGC > ECG > EGCG on the spleen colony formation assay, EGCG > EGC > EC > ECG on inhibiting the death of cells caused by apoptosis. The results indicate that GT and GTPs may have a major radioprotective effect. Each one of the catechins was a much less effective radioprotector, suggesting that total extract or a mixture of GTPs may be more effective than individual catechins. Copyright © 2008 John Wiley & Sons, Ltd.</P>
PEGylation of Silk Fibroin Model Peptide
( Hae Yong Kweon ),( You Young Jo ),( Joo Hong Yeo ),( Soon Ok Woo ),( Sang Mi Han ),( Kwang Gill Lee ) 한국잠사학회 2010 International Journal of Industrial Entomology Vol.20 No.2
Silk fibroin model peptide, alanine pentamer was synthesized through solid-phase method and modified with poly(ethylene glycol). Nuclear magnetic resonance spectrometry and Fourier-transform infrared spectroscopy showed the conformation of alanine pentamer, β-sheet structure and random coil conformation were not changed with PEGylation. Differential scanning calorimetry showed that relatively strong exothermic peak around 180˚C by PEGylation. No cytotoxicity of PEGylated pentamer was observed by L929 cell proliferation test.
Sung, Jae Hyuck,Kim, Choong Yong,Yang, Seoung Oh,Khang, Hyun Soo,Cheong, Hae Kwan,Lee, Jong Seong,Song, Chang-Woo,Park, Jung Duck,Han, Jeong Hee,Chung, Yong Hyun,Choi, Byung Sun,Kwon, Il Hoon,Cho, Myu Informa Healthcare 2007 Inhalation toxicology Vol.19 No.1
<P> Welders are at risk of being exposed to high concentrations of welding fumes and developing pneumoconiosis or other welding-fume exposure-related diseases. Among such diseases, manganism resulting from welding-fume exposure remains a controversial issue, as although the movement of manganese into specific brain regions has been established, the similar movement of manganese presented with other metals, such as welding fumes, has not been clearly demonstrated as being similar to that of manganese alone. Meanwhile, the competition between Mn and iron for iron transporters, such as transferrin and DMT-1, to the brain has also been implicated in the welding-fume exposure. Thus, the increased signal intensities in the basal ganglia, including the globus pallidus and subcortical frontal white matter, based on T1-weighted magnetic resonances in welders, require further examination as regards the correspondence with an increased manganese concentration. Accordingly, to investigate the movement of manganese after welding-fume exposure, 6 cynomolgus monkeys were acclimated for 1 mo and assigned to 3 dose groups: unexposed, low dose of (total suspended particulate [TSP] 31 mg/m3, 0.9 mg/m3 of Mn), and high dose of total suspended particulate (62 mg/m3 TSP, 1.95 mg/m3 of Mn). The primates were exposed to manual metal-arc stainless steel (MMA-SS) welding fumes for 2 h/day in an inhalation chamber system equipped with an automatic fume generator for 6 mo. Magnetic resonance imaging (MRI) studies of the basal ganglia were conducted before the initiation of exposure and thereafter every month. During the exposure, the blood chemistry was monitored every 2 wk and the concentrations of metal components in the blood were measured every 2 wk and compared with ambient manganese concentrations. The manganese concentrations in the blood did not show any significant increase until after 2 mo of exposure, and then reached a plateau after 90 days of exposure, showing that an exposure period of at least 60 days was required to build up the blood Mn concentration. Furthermore, as the blood Mn concentration continued to build, a continued decrease in the MRI T1 relaxation time in the basal ganglia was also detected. These data suggested that prolonged inhalation of welding fumes induces a high MRI T1 signal intensity with an elevation of the blood manganese level. The presence of a certain amount of iron or other metals, such as Cr and Ni, in the inhaled welding fumes via inhalation was not found to have a significant effect on the uptake of Mn into the brain or the induction of a high MRI T1 signal intensity.</P>