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      • KCI등재

        大邱地域 地殼 γ-線의 照射線量率 測定

        이모성,김위수,강희동,최문규,장시호,정춘균 대한방사선 방어학회 1994 방사선방어학회지 Vol.19 No.2

        본 연구는 대구지역의 지각 r-선에 의한 조사선량율을 측정하고 그에 따른 성분별 공간선량율 및 지역적 분포 등의 환경방사선 특성을 조사하였다. r-선 스펙트럼의 측정에는 4"ø ×4"Nal(Tl) 계측기와 휴대용 다중파고분석장치를 이용하여 이 지역내의 28개 지점에서 in-situ spectrometry를 수행하였으며, 측정된 스펙트럼으로부터 조사선량율을 환산하여 지각 r-선의 총선량율과 일반적으로 자연방사능의 주종이 되는 ?K, ?U계열 및 ?Th계열의 성분별 조사선량율을 구하였다. 조사결과 대구지역의 지각 r-선에 의한 평군조사선량율은 9.4 μR/h였으며 지점별 분포는 7.6∼11.0 μR/h범위로 다소 차이를 보였다. 측정시에 수반되는 기후나 우주선 등에 따른 일변화폭을 고려한다면 지점간의 차이는 주로 표토층의 자연방사성핵종인 ?K, ?U계열 및 ?Th계열의 핵종에 기인함을 알 수 있었으며, 성분별 선량율은 ?K2.9∼4.6 μR/h, ?U계열1.2∼3.1 μR/h, ?Th계열2.5∼5.0 μR/h의 분포를 나타냈다. This study concerns about the measurement and the investigation of environmental radiation characteristics which the components and the distribution of exposure rates by terrestrial r-rays in Taegu area. A 4"ø ×4"Nal(Tl) scintillation detector with a multichannel analyzer was used in the measurement of r-rays as a part of in-situ spectrometry at twenty eight different locations in this area. The conversion into the exposure rate from the measured r-rays spectrum has been carried out leading to a net exposure rate and component ones by ?K, ?U series and ?Th series products which are known by the major parts in the terrestrial r-rays generally. As a result, the average exposure rate by the terrestrial r-rays in Taegu area is 9.4 μR/h and the distribution of individual exposure rates shows more or less differences between these locations even after the consideration of diurnal and rearly variations which are always involved in these measurements. The component parts of exposure rates are distributed ?k2.92.9∼4.6 μR/h, ?U series1.2∼3.1 μR/h and ?Th series 2.5∼5.0 μR/h over the measured locations.

      • SCOPUSKCI등재

        Analysis of Colonoscopy Quality in Clinical Practices of Korea: Cohort Study of Patients Referred to Tertiary Hospital after Colonoscopy Examinations

        ( Chang Gyun Chun ),( Hyun Gun Kim ),( Seong Ran Jeon ),( Bong Min Ko ),( Byung Hoo Lee ),( Jin Oh Kim ) 대한장연구학회 2013 Intestinal Research Vol.11 No.3

        Background/Aims: Although the quality of colonoscopy is considered important to improve screening efficacy, there is little evidence and few statistical reports which properly reflects the colonoscopy quality of clinical practices in Korea. We aimed to investigate the quality indicators of colonoscopy performing in clinical practice. Methods: We analyzed the computerized photo-documentation files of patients who were transferred to tertiary academic hospital from private clinics or primary and secondary hospitals from January 2012 to October 2012. Quality indicators including cecal intubation rate, withdrawal time, bowel preparation status, colonoscopy report form were analyzed. Bowel preparation was assessed by 4 steps on the preparation scale (excellent, good, fair, poor). Results: A total of 198 patients (134 male, 64 female) were enrolled and analyzed. Cecal intubation rate was 91.4% (181/198) and photo-documentation of appendiceal orifice and ileocecal valve was achieved as 84.3% (167/198) and 71.7% (142/198), relatively. Overall, 83.3% of cases were adequate bowel preparation state (excellent 52%, good 31.3%). Withdrawal time could be estimated at 94.4% (187/198) of cases and mean withdrawal time of diagonostic colonoscopy (n=165) was 8.6 minutes. However, the rate of cases which withdrawal time was more than 6 minutes was 69.7% (115/165). Total of 30 institution`s colonoscopy report forms were analyzed and among nearly half enrolled institutions (46.6%, 14/30) were just recording patient`s information and colonoscopic diagnosis. Conclusions: Considerable portion of colonoscopy examination in the primary clinical practice has been performed with low procedure quality. We thus need careful attention to maintain the quality of colonoscopy in daily practice routines. (Intest Res 2013;11:198-203)

      • A Randomized, Controlled Trial of Oral Intestinal Sorbent AST-120 on Renal Function Deterioration in Patients with Advanced Renal Dysfunction

        Cha, Ran-hui,Kang, Shin Wook,Park, Cheol Whee,Cha, Dae Ryong,Na, Ki Young,Kim, Sung Gyun,Yoon, Sun Ae,Han, Sang Youb,Chang, Jae Hyun,Park, Sue K.,Lim, Chun Soo,Kim, Yon Su American Society of Nephrology 2016 CLINICAL JOURNAL- AMERICAN SOCIETY OF NEPHROLOGY Vol.11 No.4

        <P>Background and objectives The notion that oral intestinal sorbent AST-120 slows renal disease progression has not been evaluated thoroughly. In this study, we investigated the long-term effect of AST-120 on renal disease progression (doubling of serum creatinine, eGFR decrease >50%, or initiation of RRT) in patients with advanced CKD. Design, setting, participants, & measurements We prospectively recruited 579 patients (CKD stage 3 or 4) from 11 medical centers in Korea from March 4, 2009 to August 31, 2010 and randomized them into an AST-120 arm and a control arm. Patients in the AST-120 arm were given 6 g AST-120 in three divided doses per day, and those in the control arm received only standard conventional treatment (open-label design) for 36 months or until the occurrence of primary outcomes. Results Levels of serum and urine indoxyl sulfate and beta 2-microglobulin decreased throughout the study period in both treatment arms; however, there was not a significant difference in change in uremic toxins in the AST-120 and control arms. The two arms were not different in the occurrence of composite primary outcomes (100 events in 272 individuals in the AST-120 arm and 100 events in 266 individuals in the control arm; hazard ratio, 1.12; 95% confidence interval, 0.85 to 1.48; log-rank P=0.45). The decline in eGFR and change in proteinuria were similar in the two treatment arms over time (Prandomization-time=0.64 and Prandomization-time=0.16, respectively). There was no difference in mortality (nine deaths in the AST-120 arm and 11 deaths in the control arm; log-rank P=0.73) or unplanned hospitalizations (102 in the AST-120 arm and 109 in the control arm; log-rank P=0.76) in the two treatment arms. There was no significant difference of the health-related quality of life score between the two arms. Conclusions Long-term use of AST-120 added to standard treatment did not change renal disease progression, proteinuria, mortality, and health-related quality of life in patients with advanced renal dysfunction.</P>

      • KCI등재

        매립지 복토용 슬러지 고화물내 이산화탄소 생광물화 고정균 분석 및 생광물화능 평가

        안창민(Chang Min Ahn),배영신(Young Shin Bae),함종헌(Jong Heon Ham),천승규(Seung Kyu Chun),김창균(Chang Gyun Kim) 大韓環境工學會 2013 대한환경공학회지 Vol.35 No.8

        본 연구에서는 실제 매립장에 매립되어 있는 슬러지 고화물을 대상으로 생광물화 미생물 종분석을 위한 기초 연구를 수행 하였고, 또한 분석된 미생물을 배양하여 일반적으로 알려진 생광물화균과의 대조 실험을 통해 토착 미생물의 carbonate 생성능을 기기분석을 통해 비교 평가하였다. 시료내 미생물 종분석을 16S rDNA 시퀀스 분석을 통해 수행해본 결과, 다양한 미생물종이 관찰되었으며, 특히 생광물화 기작에 관여한다고 알려진 호기성 토양 미생물의 한종인 Bacillus megaterium과 금속을 환원시켜 미네랄염 상태로 전환시키는 Alkaliphilus metalliredigens의 근연종을 확인 하였다. 복토재에서 분리 배양한 균주를 이용하여 실험을 수행한 결과, 생광물화 균주가 주입된 실험군에서 미생물이 주입되지 않은 대조군보다 이산화탄소의 감소량이 더 컸다. 이와 연계하여 반응후 열중량분석기(TG-DTA)를 이용하여 탄산염(carbonate minerals)을 정량한 결과, 미생물이 주입된 실험군에서 대조군에 비해 약 30% 정도 더 생성된 것을 확인 하였다. 이러한 실험 결과로 비춰 볼 때 열중량분석법(TG-DTA)은 이산화탄소의 생물학적 전환에 의해 생성된 탄산염물의 정략적 분석에 적합할 것으로 판단된다. 이를 종합해 보면 복토재로 현장 매립된 슬러지 고화물은 매립장에서 표면 발산되는 이산화탄소의 자연적인 탄산염 전환 매체로서 적용이 가능할 것으로 판단된다. This study was performed to determine whether biomineralization microbes were actively present underneath landfill cover soil producing biocalcification. From this, various types of microbes were observed. Among them, two species were dominantly found; Bacillus megaterium and Alkaliphilus metalliredigens that were known as biominerlization bacteria. With those microbes, CO₂ was more highly consumed than without bacteria. In response, the calcium carbonate mineral was produced at 30% (wt) greater than that of the control. At the same time, TG-DTA was successfully used for quantification of CO₂ consumed forming calcium carbonate minerals resulting from biocalcification. It was decided that the presence of solidified sewage sludge cake utilized as a cover soil in the landfill could efficiently contribute to possible media adaptably and naturally sequestering CO₂ producing from the landfill.

      • KCI등재

        전 복강경 술식에 의한 간 절제술에 대한 경험

        김창균(Chang Gyun Kim),윤유석(Yoo-Seok Yoon),한호성(Ho-Seong Han),신상현(Sang-Hyun Shin),전광식(Kwang-Sik Chun),장진영(Jin-Young Jang),서경석(Kyung-Suk Suh),김선회(Sun-Whe Kim),이건욱(Kuhn Uk Lee),박용현(Yong-Hyun Park) 대한외과학회 2007 Annals of Surgical Treatment and Research(ASRT) Vol.73 No.6

        Purpose: The aim of this study is to assess the feasibility and clinical outcomes of laparoscopic liver resection by reviewing our experience of laparoscopic liver resection performed in a single institution. Methods: We retrospectively analyzed the clinical outcome of 64 patients that had undergone laparoscopic liver resection for various liver diseases between May 2003 and June 2006. Results: The patients were composed of 36 men and 28 women, with a mean age of 56.9 years. Indications for laparoscopic liver resection included 37 cases of a tumor (20 hepatocellular carcinomas, 8 metastatic cancers and 9 benign tumors) and 25 cases of IHD stones. The surgical procedures were 19 tumorectomy cases, 24 left lateral sectionectomy cases, 15 left hepatectomy cases, 4 right posterior sectionectomy cases and 2 right hepatectomy cases. The mean surgical time was 280.3 minutes. Intraoperative transfusion was required for 18 patients (28.1%). There was one postoperative death (1.6%) due to biliary sepsis after a left lateral sectionectomy for an IHD stone. Postoperative complications developed in 9 cases (14.0%) (2 intraabdominal abscesses, 1 hematoma, 1 bile leakage, 1 ascites, 1 gastric variceal bleeding, 1 ulcer bleeding and 1 anastomosis leakage), all of which were improved by conservative management. The mean postoperative hospital stay was 11.0 days. Conclusion: Our experience shows that laparoscopic liver resection is a feasible operation and is comparable to surgery with the open method. However, a prospective comparative study with long term follow-up is needed to confirm the equivalence of the procedures.

      • KCI등재후보

        침구경락 음양론의 새로운 발전, 기능적 뇌 척주요법 FCST

        인창식 ( Chang Shik Yin ),고형균 ( Hyeong Gyun Koh ),이영진 ( Young Jin Lee ),전세일 ( Sae Il Chun ),이영준 ( Young Jun Lee ) 대한경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.4

        Objectives: Functional Cerebrospinal Therapy (FCST) is a new physiologic therapeutics developed in Korea as a meridian yinyang balance approach. The theory of yinyang balance has been at the core of health enhancement approach of meridian and acupuncture medicine ever since its start. Methods: Introductory overview of FCST is presented in relation with meridian yinynag balance theory. Results: As the temporomandibular joint (TMJ) and related tissues have direct interconnection with brainstem proprioceptive or motor systems and the face is where all the meridians converge, FCST applies a fine adjustment of the posture of TMJ as a treatment tool for neurologic conditions or meridian imbalances. Conclusions: Highly sophisticated diagnostic and therapeutic techniques to adjust various subset aspects of yinyang balance are developed within FCST, which is supposed to be one of major contributions to natural healing.

      • 색채자극에 따른 심박변이도 변화와 한열조습변증의 상관성

        인창식 ( Chang-shik Yin ),김선현 ( Sun Hyun Kim ),이능기 ( Neung-gi Lee ),이우철 ( Woo-cheol Lee ),고형균 ( Hyeong-gyun Koh ),박영배 ( Young-bae Park ),전세일 ( Sae-il Chun ) 대한한의진단학회 2006 大韓韓醫診斷學會誌 Vol.10 No.2

        Objective: Biologic responses to color stimulation was observed and analyzed in relation with Korean medicine diagnostics. Methods: Twelve volunteers participated and completed the questionnaire on Hanyeol or Joseup patterns of Korean medicine diagnostics. Standard deviation of RR intervals (SDNN), an overall indicator of heart rate variability, was measured while wearing partially transparent acetate film glasses of various colors: (1) transparency or black, (2) red, green, or blue, or (3) cyan, or yellow. Results: Different responses to the color environmental stimulation were observed. Yeol pattern score was inversely related with the SDNN value under red color stimulation. Conclusion: This line of observations may serve as a basis of clinical application of color therapy, in particular, in relation with pattern diagnosis of Korean medicine, and may be applied in combination with existing electrodermal meridian measurement systems for better eval-uation of Gi (life energy) phenomenon.

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