Risk Factors for Cervical Cancer in Rural Areas of Wuhan China: a Matched Case-control Study

Zhang, Bin,Zhou, Ai-Fen,Zhu, Chang-Cai,Zhang, Ling,Xiang, Bing,Chen, Zhong,Hu, Rong-Hua,Zhang, Ya-Qi,Qiu, Lin,Zhang, Yi-Ming,Xiong, Chao-Du,Du, Yu-Kai,Shi, Yu-Qin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Cervical cancer is a serious public health problem in developing countries. We investigated possible risk factors for cervical cancer in rural areas of Wuhan China using a matched case-control study with 33 women diagnosed with cervical cancer and 132 healthy women selected from the same area as matched controls. A questionnaire, which included questions about general demography conditions, environmental and genetic factors, the first sexual intercourse, first marriage age, age at first pregnancy, pregnancy first child's age, female personal health history, social psychological factors, dietary habits, smoking and alcohol status and other living habits was presented to all participants. At the same time, HPV infection of every participant was examined in laboratory testing. Results showed HPV infection (P<0.000, OR=23.4) and pregnancy first child's age (P<0.000, OR=13.1) to be risk factors for cervical cancer. Menopause (P=0.003, OR=0.073) was a protective factor against cervical cancer. However, there was no indication of associations of environmental (drinking water, insecticide, disinfectant) genetic (cancer family history), or life-style factors (smoking status, alcohol status, physical training, sleep quality), including dietary habits (intake of fruit and vegetable, meat, fried food, bean products and pickled food) or social psychological factors with cervical cancer. The results suggest that the risk of cervical cancer in Chinese rural women may be associated with HPV infection, menopause and the pregnancy first child's age.

Two New Species of the Genus Allozelotes Yin & Peng, 1998 (Araneae, Gnaphosidae) from China

Yang Zi-Zhong, Zhang Zi-Sheng, Zhang Yao-Guang, Joo Pil Kim(김주필) 한국거미연구소 2009 한국거미 Vol.25 No.1-2

중국 Yunnan 지역에서 채집한 수리거미과의 Allozelotes 속의 2 신종을 기재하여 보고하는 바이다. 즉 Allozelotes songi sp. nov.와 A. microsaccatus sp. nov. 이다. 표본은 SWUC와 CDLC에 보관한다. 측정치는 millimeters이다. Two new species of the genus Allozelotes collected from Yunnan, China, are described and illustrated: Allozelotes songi sp. nov. and A. microsaccatus sp. nov. Type specimens are respectively deposited in School of Life Science, Southwest University(SWUC) and College of Life Science and Chemistry, Dali University(CDLC). All measurements given are in millimeters.

닫혀진 보제 끈 이론의 새로운 양자화

한승기, Wu Ke, Zhang Yuan-Zhong 忠北大學校部設基礎科學硏究所 1987 自然科學硏究 Vol.1 No.1

-본문참고-

Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transdermal Delivery for Treatment of Psoriasis

( Zhong Wen Chen ),( Yin Bing Zhang ),( Xaing Jun Chen ),( Xiao Liu ),( Zhen Wang ),( Xi Kun Zhou ),( Ji Qiu ),( Nan Nan Zhang ),( Xiu Teng ),( Yong Qiu Mao ),( Chang Yong Liu ),( Yu Quan Wei ),( Jion 대한피부과학회 2015 Annals of Dermatology Vol.27 No.2

Background: Psoriasis is an autoimmune disease that is caused by a shift in the Th1/Th2 balance toward Th1- dominant immunity. It has been established as an effective treatment to counteract psoriasis by subcutaneous injection of recombinant interleukin (IL)-4, and IL-4 gene therapy by topical transdermal penetration has shown its antipsoriatic effect in mice. Retinoic acid (RA) and dimethylsulfoxide can increase the efficiency of gene transfection in the topical transdermal delivery system. Objective: We investigated whether RA could improve anti-psoriasis efficiency using IL-4 expression plasmid pORF-mIL-4 (pIL-4) via transdermal delivery system in K14-vascular endothelial growth (K14- VEGF) factor transgenic mice. Methods: After pretreatment with RA, plasmid pIL-4 in 10% dimethylsulfoxide was applied to the ear skin by topical transdermal penetration. Hematoxylin- eosin staining and immunohistochemistry were performed with ear samples to evaluate anti-psoriasis efficiency in mice. Results: The psoriasis pathological features were relieved and psoriasis-associated factors were significantly reduced. Conclusion: Our results reveal that topical application of pIL-4 in dimethylsulfoxide by transdermal delivery with RA pretreatment can improve psoriasis significantly.(Ann Dermatol 27(2) 121∼127, 2015)

Personnel Localization Algorithm of Prison Supervision System Based on RFID

Zhang Yuping,Chang Ying,Li Chen,Zhang Zhong 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.12

The particularity of the prison decides the importance of its security system, and how to improve the accuracy of personnel positioning for prison monitoring system is the problem to be solved to realize intelligent prison monitoring management. RFID positioning technology with non line-of-sight transmission and large transmission range is widely applied in the personnel positioning system. RFID technology is used to design the monitoring and management system of prison in this paper. The Trilateral Ranging Method was adopted to realize personnel positioning. RSSI positioning algorithm its technology is relatively simple was adopted when calculating the trilateral distance and correcting the errors in order to improve the positioning precision. Simulation test results show that the positioning precision for the distance between a single reader and the tag is increased by 2.17% on average, up to 4.54% after the error correction. The personnel location coordinates, X direction average error is 2.96%, average error is 3.12%, Y direction, and meeting the requirements of the system design.

Retinoic Acid Promotes Interleukin-4 Plasmid-Dimethylsulfoxide Topical Transdermal Delivery for Treatment of Psoriasis

( Zhong Wen Chen ),( Yin Bing Zhang ),( Xaing Jun Chen ),( Xiao Liu ),( Zhen Wang ),( Xi Kun Zhou ),( Ji Qiu ),( Nan Nan Zhang ),( Xiu Teng ),( Yong Qiu Mao ),( Chang Yong Liu ),( Yu Quan Wei ),( Jion 대한피부과학회 2015 Annals of Dermatology Vol.27 No.3

Background: Psoriasis is an autoimmune disease that is caused by a shift in the Th1/Th2 balance toward Th1- dominant immunity. It has been established as an effective treatment to counteract psoriasis by subcutaneous injection of recombinant interleukin (IL)-4, and IL-4 gene therapy by topical transdermal penetration has shown its antipsoriatic effect in mice. Retinoic acid (RA) and dimethylsulfoxide can increase the efficiency of gene transfection in the topical transdermal delivery system. Objective: We investigated whether RA could improve anti-psoriasis efficiency using IL-4 expression plasmid pORF-mIL-4 (pIL-4) via transdermal delivery system in K14-vascular endothelial growth (K14- VEGF) factor transgenic mice. Methods: After pretreatment with RA, plasmid pIL-4 in 10% dimethylsulfoxide was applied to the ear skin by topical transdermal penetration. Hematoxylin- eosin staining and immunohistochemistry were performed with ear samples to evaluate anti-psoriasis efficiency in mice. Results: The psoriasis pathological features were relieved and psoriasis-associated factors were significantly reduced. Conclusion: Our results reveal that topical application of pIL-4 in dimethylsulfoxide by transdermal delivery with RA pretreatment can improve psoriasis significantly. (Ann Dermatol 27(2) 121∼127, 2015)

Application of Terahertz Spectroscopy and Imaging in the Diagnosis of Prostate Cancer

Zhang, Ping,Zhong, Shuncong,Zhang, Junxi,Ding, Jian,Liu, Zhenxiang,Huang, Yi,Zhou, Ning,Nsengiyumva, Walter,Zhang, Tianfu Optical Society of Korea 2020 Current Optics and Photonics Vol.4 No.1

The feasibility of the application of terahertz electromagnetic waves in the diagnosis of prostate cancer was examined. Four samples of incomplete cancerous prostatic paraffin-embedded tissues were examined using terahertz spectral imaging (TPI) system and the results obtained by comparing the absorption coefficient and refractive index of prostate tumor, normal prostate tissue and smooth muscle from one of the paraffin tissue masses examined were reported. Three hundred and sixty cases of absorption coefficients from one of the paraffin tissues examined were used as raw data to classify these three tissues using the Principal Component Analysis (PCA) and Least Squares Support Vector Machine (LS-SVM). An excellent classification with an accuracy of 92.22% in the prediction set was achieved. Using the distribution information of THz reflection signal intensity from sample surface and absorption coefficient of the sample, an attempt was made to use the TPI system to identify the boundaries of the different tissues involved (prostate tumors, normal and smooth muscles). The location of three identified regions in the terahertz images (frequency domain slice absorption coefficient imaging, 1.2 THz) were compared with those obtained from the histopathologic examination. The tissue tumor region had a distinctively visible color and could well be distinguished from other tissue regions in terahertz images. Results indicate that a THz spectroscopy imaging system can be efficiently used in conjunction with the proposed advanced computer-based mathematical analysis method to identify tumor regions in the paraffin tissue mass of prostate cancer.

The Outlier Detection Algorithm Based on Cumulative Holoentropy in Clustering Subspace

Zhang Zhong-ping,Sun Ying,Fang Chun-zhen,Wang Ying 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.10

Subspace outlier mining has a very important significance in big data analysis. To a large extent, subspace clustering algorithm has impact on the efficiency of mining outliers in subspaces. To solve the problem that CMI method selects best clustering subspaces unstably and complexly, formulas of chain rule of Cumulative Entropy, Cumulative Total Correlation and Cumulative Holoentropy were given. Cumulative Holoentropy was used to mine the best clustering subspaces on continuous data sets in which outliers were detected. Subspace outlier detection algorithm based on Cumulative Holoentropy was then proposed. Finally, the validity and scalability of proposed method were tested on real datasets and virtual datasets. Experiment shows that the efficiency of mining outliers in subspaces is enhanced by the proposed algorithm.

Effect of proton irradiation on interfacial and electrical performance of N+Np+ InP/InGaAs hetero-junction

Zhang Chen,Su Yongbo,Mei Bo,Yang Feng,Zhang Jialin,Yun Huanqing,Liu Bo,Sun Yi,Zhang Haiming,Jin Zhi,Zhong Yinghui 한국물리학회 2023 Current Applied Physics Vol.48 No.-

InP-based hetero-junction bipolar transistors (HBTs) are attractive for various millimeter-wave and terahertz electronics due to their ultrahigh frequency performance. Therefore, the study of their irradiation reliability is extremely urgent. In this work, 2 MeV proton irradiation experiment has been carried out on self-fabricated N+Np+ InP/InGaAs hetero-junction. The degradation mechanisms have systematically been studied after exposure to protons of 5 × 1013 H+/cm2. The voltage range of recombination current at low forward bias has been largely expanded from 0-0.2 V to 0–0.6 V. Furthermore, the interface states properties have been characterized by utilizing the frequency-dependent conductance technique, the interface states density (Dit) has increased from approximately 9.02 × 1012 cm-2 eV-1–1.99 × 1013 cm-2 eV-1 to 9.51 × 1012 cm-2 eV-1–2.00 × 1013 cm-2 eV-1 after irradiation. The study would be great significance for understanding the evolution of proton irradiation on relative devices.

Physical properties and chemical composition of the cores in the California molecular cloud

Zhang, Guo-Yin,Xu, Jin-Long,Vasyunin, A. I.,Semenov, D. A.,Wang, Jun-Jie,Dib, Sami,Liu, Tie,Liu, Sheng-Yuan,Zhang, Chuan-Peng,Liu, Xiao-Lan,Wang, Ke,Li, Di,Wu, Zhong-Zu,Yuan, Jing-Hua,Li, Da-Lei,Gao, Springer-Verlag 2018 Astronomy and astrophysics Vol.620 No.-

<P><I>Aims.</I> We aim to reveal the physical properties and chemical composition of the cores in the California molecular cloud (CMC), so as to better understand the initial conditions of star formation.</P><P><I>Methods.</I> We made a high-resolution column density map (18.2′′) with <I>Herschel</I> data, and extracted a complete sample of the cores in the CMC with the fellwalker algorithm. We performed new single-pointing observations of molecular lines near 90 GHz with the IRAM 30m telescope along the main filament of the CMC. In addition, we also performed a numerical modeling of chemical evolution for the cores under the physical conditions.</P><P><I>Results.</I> We extracted 300 cores, of which 33 are protostellar and 267 are starless cores. About 51% (137 of 267) of the starless cores are prestellar cores. Three cores have the potential to evolve into high-mass stars. The prestellar core mass function (CMF) can be well fit by a log-normal form. The high-mass end of the prestellar CMF shows a power-law form with an index <I>α</I> = −0.9 ± 0.1 that is shallower than that of the Galactic field stellar mass function. Combining the mass transformation efficiency (<I>ε</I>) from the prestellar core to the star of 15 ± 1% and the core formation efficiency (CFE) of 5.5%, we suggest an overall star formation efficiency of about 1% in the CMC. In the single-pointing observations with the IRAM 30m telescope, we find that 6 cores show blue-skewed profile, while 4 cores show red-skewed profile. [HCO<SUP>+</SUP>]/[HNC] and [HCO<SUP>+</SUP>]/[N2H<SUP>+</SUP>] in protostellar cores are higher than those in prestellar cores; this can be used as chemical clocks. The best-fit chemical age of the cores with line observations is ~5 × 10<SUP>4</SUP> yr.</P>