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- 저자 : Yun-Ta Liu (검색결과 3 건)
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Wen-Pin Lee,Mei-Ling Li,Yun-Ta Liu,Chung-Ming Lee,Hsien-Tsung Yao 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.1
Qing-Yu-Mu (QYM) is an herbal formula used to prevent and treat liver disease in Taiwan. In this study, the hepatoprotective effects of QYM were evaluated in two experimental models. First, rats were fed a high-frying oil (FO) diet containing 1.25% QYM for 5 weeks to investigate effects of QYM on hepatic oxidative stress and antioxidant enzyme activities. Then, protective effects of QYM on carbon tetrachloride (CCl4)-induced chronic liver injury were evaluated. Results show that QYM treatment reduced FO diet-induced hepatic lipid peroxidation and reactive oxygen species levels and increased glutathione (GSH) S-transferase activity. A higher reduced GSH/oxidized GSH (GSSG) ratio was observed after QYM treatment. Furthermore, QYM ameliorated CCl4-induced liver injury by reducing the activity of plasma alanine aminotransferase and histological lesions in the liver. QYM also increased the level of hepatic GSH and activities of GSH peroxidase and superoxide dismutase. Finally, chlorogenic acid, chrysophanol, and apigenin were found to be present in relative abundance in QYM. Results show that QYM may exhibit a hepatoprotective effect by reducing oxidative stress and increasing antioxidant activity in the liver.
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Type 2 Diabetes Mellitus Increases Peritonsillar Abscess Susceptibility: Real-World Evidence
Ching-Lung Wu,Ming-Shao Tsai,Ta-Jen Lee,Yun-Ting Wang,Chia-Yen Liu,Yao-Hsu Yang,Yao-Te Tsai,Cheng-Ming Hsu,Ching-Yuan Wu,Pey-Jium Chang,Geng-He Chang 대한이비인후과학회 2021 Clinical and Experimental Otorhinolaryngology Vol.14 No.3
Objectives. Type 2 diabetes mellitus (T2DM) is a risk factor for deep neck infection (DNI) and leads to complications and poor outcomes. Our study aimed to investigate the risk, prognosis, and complications of peritonsillar abscess (PTA) in patients with T2DM. Methods. We extracted data of patients newly diagnosed as having T2DM between January 2000 and December 2011 from Taiwan’s National Health Insurance Research Database. These patients were matched with patients without T2DM, and PTA incidence was compared between both cohorts. Results. In total, 67,852 patients with and 135,704 patients without T2DM were enrolled. PTA incidence was significantly higher in patients with T2DM (incidence rate ratio, 1.91; P<0.001); moreover, PTA incidence was higher at 1 to 5 years after T2DM diagnosis than at <1 and >5 years after T2DM diagnosis. Cox regression analysis showed that patients with T2DM had an approximately 2-fold higher PTA risk (adjusted hazard ratio [aHR]: 1.89, P<0.001). Patients with a higher adapted Diabetes Complications Severity Index (aDCSI) had higher PTA risk than those with a lower aDCSI (aHRs: 2.17 for aDCSI ≥1, P=0.006 and 1.81 for aDCSI=0, P=0.002). T2DM patients with a high aDCSI (≥1) had a nonsignificantly longer hospitalization duration and a higher rate of DNI complications than did those with a low aDCSI (=0). Conclusion. In patients with T2DM, PTA incidence was relatively high, and it increased with T2DM severity. Moreover, T2DM patients should be particularly careful about PTA within 1 to 5 years after the diagnosis, and physicians should keep in mind that the prognosis of PTA was correlated with T2DM severity.
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Sloshing suppression by floating baffle
Kang, Hooi-Siang,Md Arif, Ummul Ghafir,Kim, Kyung-Sung,Kim, Moo-Hyun,Liu, Yu-Jie,Lee, Kee-Quen,Wu, Yun-Ta Techno-Press 2019 Ocean systems engineering Vol.9 No.4
Sloshing is a phenomenon which may lead to dynamic stability and damages on the local structure of the tank. Hence, several anti-sloshing devices are introduced in order to reduce the impact pressure and free surface elevation of liquid. A fixed baffle is the most prevailing anti-sloshing mechanism compared to the other methods. However, the additional of the baffle as the internal structure of the LNG tank can lead to frequent damages in long-term usage as this structure absorbs the sloshing loads and thus increases the maintenance cost and downtime. In this paper, a novel type of floating baffle is proposed to suppress the sloshing effect in LNG tank without the need for reconstructing the tank. The sloshing phenomenon in a membrane type LNG tank model was excited under sway motion with 30% and 50% filling condition in the model test. A regular motion by a linear actuator was applied to the tank model at different amplitudes and constant period at 1.1 seconds. Three pressure sensors were installed on the tank wall to measure the impact pressure, and a high-speed camera was utilized to record the sloshing motion. The floater baffle was modeled on the basis of uniform-discretization of domain and tested based on parametric variations. Data of pressure sensors were collected for cases without- and with-floating baffle. The results indicated successful reduction of surface run-up and impulsive pressure by using a floating baffle. The findings are expected to bring significant impacts towards safer sea transportation of LNG.
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