Effect of bio-template on the properties of SiO2/Al2O3 composites for drug delivery

Long-Yue Meng,Weiqi Jiang,Wen Xiang Piao,Wan Meng 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.37 No.-

In this study, SiO2/Al2O3 composites (C-SLNs) were successfully synthesized using chitosan as thetemplate for drug delivery. The C-SLNs had higher specific surface areas (244–607 m2/g), total porevolumes (0.19–0.34 cm3 g 1), and narrow mesopore size distribution. The porosity of the C-SLNsprepared under high Si/Al ratio conditions was achieved mostly by the formation of wider pores thatwere distributed in the meso-/macro-pores. And, the C-SLNs were used as a levofloxacin carrier to studyits drug release behavior, which exhibited an initial fast release followed by a sustained release andantibacterial effectiveness over a long period.

An Approach to Transit Path Design Using GIS

S.V.C. Sekhar, Wen Long Yue, M.A.P.Taylor 서울시립대학교 도시과학연구원 2004 International journal of urban sciences (IJUS) Vol. No.

The design of public transportation networks is complex and can include conflicting objectives. Networks designed to minimise travel time may not fulfil the requirement of maximum coverage and accessibility. In this context, a multi-criteria approach for transit alignment design has been developed to maximise a range of objectives using census data. Whenever a subdivision is developed in a suburban region of a medium sized city, transit operators often receive requests to link the city centre with the new locality via new routes. Traditionally, implementation of routing a new bus service is based on a ‘common sense’approach. This can lead to the development of an irrational network of public transport routes. This research offers an alternative approach, which essentially optimises ulticriteria for planning transit routes. This research has proved that it is worth considering such options for connecting origin-destination zones with a new bus service.

Signal Metering 운영기법을 활용한 회전교차로의 지체시간 분석 연구

안홍기,Yue Wen Long,배기목 국회입법조사처 2016 입법과 정책 Vol.8 No.2

A signal metering roundabout is able to reduce delay times, particularly during peak periods. Over time a number of studies have analyzed and assessed its performance. Since 2011, Korea also has adopted roundabouts as intersection control devices. However, the majority of studies regarding metering roundabouts have focused on one traffic signal metering roundabout only. Furthermore, Korea uses a different roundabout analysis method (the aggregated method, rather then the lane-by-lane method used by Australia and the US) due the shortage of data and history of use in Korea. An accurate analysis of multi-lane roundabouts in Korea is thus limited. This study, therefore, has compared both methods based on the Old Belair road metering roundabout in Adelaide which is operated by two traffic signals and consists of two approach lanes entering and exiting. The results from the analysis showed that the metering roundabout can decrease the delay time of the dominant approach significantly, however, the delay time of other approaches was increased under both models. Moreover, lane-by-lane method showed that the metering roundabout can decrease the total roundabout delay time, whereas the metering roundabout increases the total delay time using the aggregated method, and their difference is approximately 1.7s/veh. Signal Metering 회전교차로는 첨두시 지체도 감소에 효과적이다. 2011년 회전교차로의 도입으로 인한 국내 회전교차로에 대한 연구는 활발하지만 주 접근로의 효과분석에 편중되어 있다고 할 수 있다. 또한, 회전교차로가 활성화되어 있는 미국 및 호주(차로별 분석)와 다른 접근로 통합 분석 방법을 사용하고 있다. 이 방식은 다차로 회전교차로의 분석에 있어 정밀한 분석이 어렵다는 단점이 있다. 따라서 본 연구는 실제 Metering 기법으로 운영되는 호주의 Signal Metering 회전교차로를 대상으로 차로별 분석과 통합분석의 비교 분석을 통한 운영 효과를 살펴보고자 한다. 효과적인 분석을 위해 회전교차로의 분석에 널리 사용되는 Micro-simulation software인 AIMSUN7을 사용하였으며, Metering 회전교차로의 운영 시 주 접근로의 지체도가 큰 폭으로 감소하는 것으로 나타났다. 또한, 차로별 분석방법과 통합 분석 방법의 지체시간 분석결과 Metering 운영기법을 사용할 경우 교차로 전체의 지체시간은 차로별 분석 144.23초/대, 통합분석 145.95초/대로 두 방법 간 1.7초/대의 차이가 발생하는 것으로 분석되었다.

Nanoscale Printing Technique and its Applications in Nanophotonics

Huacun Wang,Long Wen,Xin Hu,Yan Yu,Yue Zhao,Qin Chen 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.9

"Printing" is an ancient technique for recording and publishing. Recently, this technique has extended its activities down to a nanometer scale. In this paper, we review the progress of the printing technique focusing on the most recent developments of one technique called "transfer printing" and its applications in nanophotonics.

Effect of preparation methods on the performance of CeO2/Al2O3catalysts for selective catalytic reduction of NO with NH3

Rui-Tang Guo,Yue Zhou,Wei-Guo Pan,Jie-nan Hong,Wen-long Zhen,Qiang Jin,Cheng-gang Ding,Shi-yi Guo 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.6

CeO2/Al2O3 catalysts prepared by three methods were investigated for selective reduction of NO with NH3. It was found that the catalyst prepared by the single step sol–gel method had the best SCR activity and SO2 resistance performance. From the results of BET, XRD, TPD and TPR, it can be concluded that large surface area, strong interaction, highly dispersed nano-crystalline ceria, high NH3 adsorption capacity and good redox ability might be the main reasons for the excellent performance of CeO2/Al2O3catalyst prepared by the single step sol–gel method.

Effect of Cu doping on the SCR activity of CeO2 catalyst prepared by citric acid method

Rui-Tang Guo,Wen-long Zhen,Wei-Guo Pan,Yue Zhou,Jie-nan Hong,Hong-jian Xu,Qiang Jin,Cheng-gang Ding,Shi-yi Guo 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

CeO2–CuO catalyst prepared by citric acid method was investigated for selective catalytic reduction of NO with NH3. The activity of the CeO2 catalyst was enhanced about 8–27% in the temperature range of 125–225 ℃ at a space velocity of 28,000 h 1 by the addition of Cu. It was found that the state of Cu species had great impact on the SCR performance of CeO2–CuO catalyst. Cu2+ can enhance the low temperature activity of SCR reaction, while CuO would promote NH3 oxidation before SCR reaction at high temperature, which would cause the decrease of its high temperature SCR activity.

<i>Chd7</i> Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish

Liu, Zhi-Zhi,Wang, Zi-Long,Choi, Tae-Ik,Huang, Wen-Ting,Wang, Han-Tsing,Han, Ying-Ying,Zhu, Lou-Yin,Kim, Hyun-Taek,Choi, Jung-Hwa,Lee, Jin-Soo,Kim, Hyung-Goo,Zhao, Jian,Chen, Yue,Lu, Zhuo,Tian, Xiao-L Elsevier 2018 The American journal of pathology Vol.188 No.4

<P>Coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies/deafness (CHARGE) syndrome is a congenital disorder affecting multiple organs and mainly caused by mutations in CHD7, a gene encoding a chromatin-remodeling protein. Immunodeficiency and reduced T cells have been noted in CHARGE syndrome. However, the mechanisms underlying T lymphopenia are largely unexplored. Herein, we observed dramatic decrease of T cells in both chd7knockdown and knockout zebrafish embryos. Unexpectedly, hematopoietic stem and progenitor cells and, particularly, lymphoid progenitor cells were increased peripherally in nonthymic areas in chd7-deficient embryos, unlikely to contribute to the T-cell decrease. Further analysis demonstrated that both the organogenesis and homing function of the thymus were seriously impaired. Chd7 might regulate thymus organogenesis through modulating the development of both neural crest cell-derived mesenchyme and pharyngeal endoderm-derived thymic epithelial cells. The expression of faxn1, a central regulator of thymic epithelium, was remarkably down-regulated in the pharyngeal region in chd7-deficient embryos. Moreover, the T-cell reduction in chd7-deficient embryos was partially rescued by overexpressingfoxnl, suggesting that restoring thymic epithelium may be a potential therapeutic strategy for treating immunodeficiency in CHARGE syndrome. Collectively, the results indicated that chd7 was critical for thymic development and T-lymphopenia in CHARGE syndrome may be mainly attributed to the defects of thymic organogenesis. The current finding may benefit the diagnosis and therapy of T lymphopenia and immunodeficiency in CHARGE syndrome.</P>

Chlorophyll Fluorescence Characteristics and Rapid Light Response Curves of Alpine Rhododendron

Yuan-Huan Liu,Fang-Li Liu,Bo Long,Xiong-Li Zhou,Xue Zhang,Yue Zhang,Wen-Li Wang,Shi-Kang Shen 한국원예학회 2019 원예과학기술지 Vol.37 No.4

The aim of this study was to determine the photosynthetic adaptability of Rhododendron species toalpine environments. The chlorophyll fluorescence parameters and rapid light response curves ofeight Rhododendron species were determined under field conditions across elevation gradients (atelevations of 2,950, 3,560, 3,660, 3,770, and 4,030 m) in the Jiaozi Mountain National NaturalReserve, Yunnan Province, southwestern China. The effect of different elevations, species, and theirinteractions significantly affected most of the chlorophyll fluorescence and rapid light response curveparameters. The variable to maximum fluorescence ratio (Fv/Fm) ranged from 0.78 to 0.81 at the fiveelevation gradients. This result indicated that the studied species were well grown and adapted to thecurrent environment. The correlation analysis indicated that the elevation was positively significantlycorrelated with the photochemical efficiency of photosystem II, electron transport rate, maximumelectron transport rate, light saturation coefficient (Ek), and chlorophyll relative content (SPAD: leafchlorophyll content index) and was negatively significantly correlated with photochemicalquenching, nonphotochemical quenching, and linear initial slope values. Although no significantrelationship was observed between the elevations and Fv/Fm, the apparent difference in Fv/Fm both atelevation gradients and elevation × species levels indicated that the Rhododendron speciesdemonstrated species-specific adaptation to the environment at different elevations. Our resultsprovided evidence that Rhododendron species exhibit variations in photosynthetic activities in analpine environment at different elevations. These differences may improve the understanding of thephysiological adaptation variations of Rhododendron species across elevation gradients in associationwith climate change in the mountains of southwestern China.