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      • Computer modeling for frequency performance of viscoelastic magneto-electro-elastic annular micro/nanosystem via adaptive tuned deep learning neural network optimization

        Guo, Xu,Liu, Yixian,Wang, Guanzhuo Techno-Press 2021 Advances in nano research Vol.11 No.2

        The presented paper is the first attempt to apply deep learning for predicting the frequency characteristics of a magneto-electro-elastic (MEE) annular nano/microdisk (MEEAD). The optimum amount of the factors participating in the mechanism of the fully connected neural network are achieved through the optimizer based on the momentum. The positive side of the mentioned approach employed in this investigation would be due to its high accuracy along with lower epochs required for training the multi-layered network. This scrutinization would be semi-computational research that estimates the vibrational behavior of a MEEAD employing a non-classical continuum model known as the modified couple stress (MCS) model. First-order shear deformation theory (FSDT) and shell model would be provided for presenting their displacement fields. Then, Kelvin-Voight theory has been applied to model the viscoelastic foundation. Its non-classical governing equations, as well as related boundary conditions (BCs) of small-scaled MEEAD, would be achieved by considering the symmetric spinning gradient along with higher-order stress tensors for the strain energy. The provided non-classical theory would be able to capture the small scale in the MEEAD employing just one length scale of a material factor, then, the mathematical modeling of MEEAD according to the classical theory would be able to be recovered from the provided model by eliminating the material length scale factor. Ultimately, the non-classical governing equations would be solved by applying the generalized differential quadrature (GDQ) approach for multifarious BCs. Moreover, parametric research has been conducted to analyze the influences of the viscoelastic foundation, length scale factor, geometry of MEE, radial and circumferential mode number, radius ratio, and BCs on the frequency behavior of the MEEAD by applying MCST. The outcomes reveal that there would be a crucial radius ratio in which the relationship between these elements and crucial inserted voltage alters from direct to indirect relation.

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        Pancreatic regulation of glucose homeostasis

        Pia V Röder,Bingbing Wu,Yixian Liu,Weiping Han 생화학분자생물학회 2016 Experimental and molecular medicine Vol.48 No.-

        In order to ensure normal body function, the human body is dependent on a tight control of its blood glucose levels. This is accomplished by a highly sophisticated network of various hormones and neuropeptides released mainly from the brain, pancreas, liver, intestine as well as adipose and muscle tissue. Within this network, the pancreas represents a key player by secreting the blood sugar-lowering hormone insulin and its opponent glucagon. However, disturbances in the interplay of the hormones and peptides involved may lead to metabolic disorders such as type 2 diabetes mellitus (T2DM) whose prevalence, comorbidities and medical costs take on a dramatic scale. Therefore, it is of utmost importance to uncover and understand the mechanisms underlying the various interactions to improve existing anti-diabetic therapies and drugs on the one hand and to develop new therapeutic approaches on the other. This review summarizes the interplay of the pancreas with various other organs and tissues that maintain glucose homeostasis. Furthermore, anti-diabetic drugs and their impact on signaling pathways underlying the network will be discussed.

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        Defense Strategy of Network Security based on Dynamic Classification

        ( Jinxia Wei ),( Ru Zhang ),( Jianyi Liu ),( Xinxin Niu ),( Yixian Yang ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.12

        In this paper, due to the network security defense is mainly static defense, a dynamic classification network security defense strategy model is proposed by analyzing the security situation of complex computer network. According to the network security impact parameters, eight security elements and classification standard are obtained. At the same time, the dynamic classification algorithm based on fuzzy theory is also presented. The experimental analysis results show that the proposed model and algorithm are feasible and effective. The model is a good way to solve a safety problem that the static defense cannot cope with tactics and lack of dynamic change.

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