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Hwa-Rang Cha,Kyung-Ho Park,Yeong-Jun Choi,Rae-Young Kim 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
This paper proposes a wireless power transfer (WPT) system to achieve high power density and constant voltage output. The proposed system consists of a doublesided LCC compensation network and a semi-bridgeless rectifier. The output voltage is controlled by using the pulse width modulation control of the semi-bridgeless rectifier switch without changing the operating frequency. Therefore, the proposed system provides a stable output voltage even under various disturbances such as input voltage and load variation. In addition, there is an advantage that the power density is improved because no additional passive elements and stages for voltage control are required. In order to confirm the validity of the proposed system, simulation results are provided.
Isolation and Characterization of Chondroitin Sulfates from the Byproducts of Marine Organisms
A-Rang Im,Joon-Soo Sim,Youmie Park,Bum-Soo Hahn,Toshihiko Toida,Yeong Shik Kim 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.4
By-products of marine organisms including salmon, skate, flatfish, and yellow goosefish were investigated to search for new source of chondroitin sulfate (CS). Agarose gel electrophoresis with chondroitinase depolymerization showed that purified chondroitin sulfate did not contain any other glycosaminoglycans. ¹H-nuclear magnetic resonance (NMR) spectra were acquired to confirm the structure and purity. The average molecular weight ranging from 22 to 64 kDa was determined by high performance size exclusion chromatography. Disaccharide compositions and purities were determined by strong anion exchange-high performance liquid chromatography (SAX-HPLC) after chondroitinase ABC depolymerization. SAX-HPLC data exhibited that the purity was from 81.7±1.3 to 114.2±2.5% and the yield was from 1.3 to 12.5%. All analytical results indicate that salmon cartilage, skate cartilage, and yellow goosefish bone could be promising sources of CS to substitute shark cartilage CS in commercial neutraceuticals.
( Jae Yeong Cho ),( Kye Hun Kim ),( Kyung Jin Lee ),( Yi Rang Yim ),( Sung Soo Kim ),( Hae Chang Jeong ),( Ki Hong Lee ),( Keun Ho Park ),( Doo Sun Sim ),( Hyun Ju Yoon ),( Nam Sik Yun ),( Young Joon 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background:Since severe tricuspid regurgitation (TR) is an uncommon fi nding which develops in various conditions, the present study aimed to investigate etiology, clinical characteristics, and predictors of reversibility in patients with severe TR. Methods:A total of 232 patients (67. 4±14. 1 years, 80 males) who were diagnosed with severe TR by echocardiography were enrolled. Severe TR was defi ned as vena contracta width greater than 0. 7 cm and systolic fi ow reversal in hepatic veins according to the current guideline of American Society of Echocardiography (ASE). Improvement of TR to moderate or less degree on follow up echocardiography was considered as reversible TR in the present study. Primary end points were adverse events at long-term follow-up. Adverse events were defi ned as all-cause death and operation due to severe TR. Results: Reversible TR was observed in 35 out of 153 patients (23. 0%). Sixty-one patients showed clinical improvement, but the degree of TR was not changed. Forty-nine patients (32%) who did not show clinical improvement despite of medical therapy eventually underwent surgical correction of TR, and 7 patients died. In addition, 17 patients died without operation, so 24 deaths (16%) were observed in total. finally, total adverse events developed in 66 patients (41%) during 2 years of follow-up period. Logistic regression analysis revealed prosthetic mitral valve was the only independent predictors of future adverse events (OR 2. 47, 95%CI 1. 05-5. 77, p=0. 038). Independent predictors of improved TR turned out to be the use of RAAS blockade (HR 3. 02, 95%CI 1. 12-8. 17, p=0. 030) and the use of spironolactone (HR 3. 39, 95%CI 1. 05-10. 90, p=0. 041). Low ejection fraction (LVEF <50%) also had a trend toward the reversibility (HR 2. 82, 95%CI 0. 94-8. 40). Conclusions:Considering results above, reversible severe TR mainly associated with left heart failure and medical treatment should be given before considering surgery for severe TR.
Isolation and Characterization of Chondroitin Sulfates from the By-products of Marine Organisms
A-Rang Im,Joon-Soo Sim,Youmie Park,Bum-Soo Hahn,Toshihiko Toida,Yeong Shik Kim 한국당과학회 2010 한국당과학회 학술대회 Vol.2010 No.1
The by-products of marine organisms including salmon, skate, flatfish, and yellow goosefish were investigated to search for new source of chondroitin sulfate. Agarose gel electrophoresis with chondroitinase depolymerization showed that purified chondroitin sulfate did not contain any other glycosaminoglycans. 1H-NMR spectra were acquired to confirm the structure and purity. The average molecular weight ranging from 22 to 64 kDa was determined by high-performance size exclusion chromatography. Disaccharide compositions and purities were determined by strong anion exchange-high performance liquid chromatography after chondroitinase ABC depolymerization. Strong anion exchangehigh- performance size exclusion chromatography data exhibited that the purity was from 81.7±1.3 to 114.2±2.5% and the yield was from 1.3 to 12.5%. All analytical results indicate that salmon cartilage, skate cartilage, and yellow goosefish bone could be promising sources of chondroitin sulfate to substitute shark cartilage chondroitin sulfate in commercial neutraceuticals.
A-Rang Im,Youmie Park,Yeong Shik Kim 한국당과학회 2011 한국당과학회 학술대회 Vol.2011 No.1
Silver nanoparticles (AgNPs) are nanoparticles of silver that between 1 nm and 100 nm in size and are prepared by reduction of Ag+ ions to Ag metal by chemical reducing agents as a common method. It has been reported that the bactericidal effects of AgNPs are dependent on size with preferential size of ~1-10 nm. In recent days biological molecules instead of chemical reducing agents have been reported to synthesize AgNPs including plant extracts, polysaccharide, fungi, DNA, yeast, and bacteria. Recently, research articles report the use of polysaccharides for the synthesis of AgNPs. Among polysaccharides, glycosaminoglycans (GAGs: Chondroitin sulfate (CS) and Acharan sulfate (AS)) exhibit diverse biological activities through interactions between physiological proteins. Owing to biological activities of GAGs, we could expect synergistic effects of GAGs-derived nanomaterials from GAGs and nanoparticles. AgNPs-GAGs represented several activities such as anti-oxidant, anti- bacterial, and wound healing. AgNPs by using the CS exhibited antioxidative, where as CS only remained almost inactive. AgNPs has no cytotoxicity on fibroblast cells. When cells were treated with AgNPs by using GAGs for 24 hr, there were no cytotoxicity effects on fibroblast cells. AgNPs-GAGs displayed significant inhibitory action against both antibiotic-susceptible and resistant strains of many strains with MIC ranging from 1 to 8 mg/ml. AgNPs-CS showed the highest inhibitory activity against Enterobacter cloacae 1321E with MICs of 1 mg/ml. At animal model, after excision skin, wound size of AgNPs-CS and AgNPs-AS ointment group was smaller than not treated and Vaseline group. Time to closure was defined as the time at which the wound bed was completely filled in with new tissue. Therefore, the utilization of such biological entities and environmentally benign solvents, and renewable materials are some of the key issues that merit important consideration in a green synthetic strategy.