Effects of a new desensitizing paste containing 8% arginine and calcium carbonate on the shear bond strength of orthodontic brackets

Yagci, Ahmet,Uysal, Tancan,Akinci, Hatice,Uysal, Banu The Korean Association Of Orthodontists 2011 대한치과교정학회지 Vol.41 No.2

Objective: The purpose of this study was to evaluate shear bond strength (SBS) and failure site location of brackets bonded to enamel with or without desensitizer application. Methods: Sixty-six freshly extracted human premolar teeth were randomly divided into 3 groups of 22. Group 1 served as the control. Desensitizer was applied to the remaining teeth at two time intervals (Group 2, bonded immediately after Pro-$Relief^{TM}$ (Colgate-Palmolive Co., New York, NY, USA) application and Group 3, bonded 30 days after Pro-$Relief^{TM}$ application with the teeth stored in artificial saliva during the 30 days). Orthodontic brackets were bonded with a light cure composite resin and cured with a halogen light. After bonding, the SBS of the brackets was tested using a universal testing device. Adhesive remnant index (ARI) scores were determined after the brackets failed. Data were analyzed with analysis of variance, Tukey's HSD, and G tests. Results: The SBS was significantly lower in Group 2 than in Groups 1 (p = 0.024) and 3 (p = 0.017). Groups 1 and Group 3 did not differ (p = 0.991). ARI scores did not differ significantly among groups. Conclusions: The Pro-$Relief^{TM}$ desensitizer agent applied immediately before bonding significantly reduces bond strength, but the SBS values still exceed the minimum 5.9 - 7.8 MPa required for adequate clinical performance. Immersing the teeth in artificial saliva for 30 days after applying the Pro-$Relief^{TM}$ desensitizer agent and before bonding increased the SBS to control levels.

Effects of conventional and modified facemask therapies on dentofacial structures

Yagci, Ahmet,Uysal, Tancan The Korean Association Of Orthodontists 2010 대한치과교정학회지 Vol.40 No.6

이번 연구의 목적은 기존의 페이스 마스크와 변형된 페이스 마스크의 치아 및 골격적 효과를 평가하고자 III급 부정교합환에서 치료군과 비치료군을 비교하였다. 24명의 환자(여자: 13명, 남자: 11)로 구성된 기존의 페이스 마스크 그룹(Group 1, mean age, $9.2{\pm}1.4$ years)과 24명의 환자(여자: 12명, 남자: 12명)로 구성된 변형된 페이스 마스크(Group 2, mean age, $9.3{\pm}1.6$ years); 그리고 21 명(여자: 11 명, 남자: 10명)으로 구성된 대조군 그룹(Group 3, mean age, $9.8{\pm}1.9$ years)으로 분류하였다. 그룹 내 그룹 간에 치료군과 대조군을 통계학적으로 분석하였다. 그룹 내 비교는 비모수적인 방법의 Wilcoxon's test으로 그룹 간의 변화는 Kruskal-Wallis test를 이용하여 분석하였다. 이후 그룹 간의 통계적인 유효성 검증을 위하여 Mann-Whitney test와 Bonferroni's correction 을 시행하였다 (p < 0.016). Group 1에서 SNB 변화가 대조군보다 적었다. SNA, ANB, SN-MP, A to N perp과 Upper lip to E plane이 증가하였다. Group 2에서는 SNB, U1-NA (mm) U1-NA ($^{\circ}$) and Pog to N perp (mm) 변화는 대조군보다 적었다. SNA, ANB, SN-MP, A to N perp과 Upper lip to E plane이 증가하였다. 변형된 페이스 마스크는 상악 열성장이 있는 III급 부정교합 환자에게 효과적으로 사용될 수 있다. 상악궁 확장을 동반한 페이스 마스크를 통하여 상악은 회전을 야기시키지 않고 전방으로 이동하였으며 모든 치료군에서 하악은 후하방으로 이동하였다. Objective: The purpose of this prospective study was to evaluate the dentofacial effects of conventional and modified facemask therapies with rapid maxillary expansion, in a group of Class III patients; and compared with an untreated control group. Methods: The conventional facemask group (Group 1) comprised of 24 patients, 13 girls and 11 boys (mean age, $9.2{\pm}1.4$ years); the modified facemask treatment group (Group 2) comprised of 24 patients, 12 girls and 12 boys (mean age, $9.3{\pm}1.6$ years); and the control group (Group 3) comprised of 21 subjects, 11 girls and 10 boys (mean age, $9.8{\pm}1.9$ years). Treatment and control changes within the groups and the differences between the groups were analyzed statistically. Intra-group comparisons were evaluated using the non-parametric Wilcoxon's test and intergroup changes were analyzed using the Kruskal-Wallis test. The statistical significance of intergroup differences was further assessed with the Mann-Whitney test for independent samples and applying Bonferroni's correction (p < 0.016). Results: In group 1, SNB changes were less than the control. There were increases in SNA, ANB, SN-MP, A to N perp and Upper lip to E plane. In group 2, SNB, U1-NA (mm) U1-NA (${\circ}$) and Pog to N perp (mm) changes were less than the control. There were increases in SNA, ANB, SN-MP, A to N perp and Upper lip to E plane. Conclusions: Modified facemask appliance can be used effectively in Class III patients with a retrognathic maxilla. Facemask therapies with expansion resulted in an anterior advancement and translation of maxilla without rotation; and the mandible moved downward and backward ward in both treatment groups.

Effects of a new desensitizing paste containing 8% arginine and calcium carbonate on the shear bond strength of orthodontic brackets

Ahmet Yagci,Tancan Uysal,Hatice Akinci,Banu Uysal 대한치과교정학회 2011 대한치과교정학회지 Vol.41 No.2

Objective: The purpose of this study was to evaluate shear bond strength (SBS) and failure site location of brackets bonded to enamel with or without desensitizer application. Methods: Sixty-six freshly extracted human premolar teeth were randomly divided into 3 groups of 22. Group 1 served as the control. Desensitizer was applied to the remaining teeth at two time intervals (Group 2, bonded immediately after Pro-Relief™ (Colgate-Palmolive Co., New York, NY, USA) application and Group 3, bonded 30 days after Pro-Relief™ application with the teeth stored in artificial saliva during the 30 days). Orthodontic brackets were bonded with a light cure composite resin and cured with a halogen light. After bonding, the SBS of the brackets was tested using a universal testing device. Adhesive remnant index (ARI) scores were determined after the brackets failed. Data were analyzed with analysis of variance, Tukey’s HSD, and G tests. Results: The SBS was significantly lower in Group 2 than in Groups 1 (p = 0.024) and 3 (p = 0.017). Groups 1 and Group 3 did not differ (p = 0.991). ARI scores did not differ significantly among groups. Conclusions: The Pro-Relief™ desensitizer agent applied immediately before bonding significantly reduces bond strength, but the SBS values still exceed the minimum 5.9 - 7.8 MPa required for adequate clinical performance. Immersing the teeth in artificial saliva for 30 days after applying the Pro-Relief™ desensitizer agent and before bonding increased the SBS to control levels.

Effects of conventional and modified facemask therapies on dentofacial structures

Ahmet Yagci,Tancan Uysal 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.6

이번 연구의 목적은 기존의 페이스 마스크와 변형된 페이스 마스크의 치아 및 골격적 효과를 평가하고자 III급 부정교합환에서 치료군과 비치료군을 비교하였다. 24명의 환자(여자: 13명, 남자: 11)로 구성된 기존의 페이스 마스크 그룹(Group 1, mean age, 9.2 ± 1.4 years)과 24명의 환자(여자: 12명, 남자: 12명)로 구성된 변형된 페이스 마스크(Group 2, mean age, 9.3 ± 1.6 years); 그리고 21명(여자: 11명, 남자: 10명)으로 구성된 대조군 그룹(Group 3, mean age, 9.8 ± 1.9 years)으로 분류하였다. 그룹 내 그룹 간에 치료군과 대조군을 통계학적으로 분석하였다. 그룹 내 비교는 비모수적인 방법의 Wilcoxon"s test으로 그룹 간의 변화는 Kruskal-Wallis test를 이용하여 분석하였다. 이후 그룹 간의 통계적인 유효성 검증을 위하여 Mann-Whitney test와 Bonferroni"s correction을 시행하였다 (p < 0.016). Group 1에서 SNB 변화가 대조군보다 적었다. SNA, ANB, SN-MP, A to N perp과 Upper lip to E plane이 증가하였다. Group 2에서는 SNB, U1-NA (mm) U1-NA (˚) and Pog to N perp (mm) 변화는 대조군보다 적었다. SNA, ANB, SN-MP, A to N perp과 Upper lip to E plane이 증가하였다. 변형된 페이스 마스크는 상악 열성장이 있는 III급 부정교합 환자에게 효과적으로 사용될 수 있다. 상악궁 확장을 동반한 페이스 마스크를 통하여 상악은 회전을 야기시키지 않고 전방으로 이동하였으며 모든 치료군에서 하악은 후하방으로 이동하였다. Objective: The purpose of this prospective study was to evaluate the dentofacial effects of conventional and modified facemask therapies with rapid maxillary expansion, in a group of Class III patients; and compared with an untreated control group. Methods: The conventional facemask group (Group 1) comprised of 24 patients, 13 girls and 11 boys (mean age, 9.2 ± 1.4 years); the modified facemask treatment group (Group 2) comprised of 24 patients, 12 girls and 12 boys (mean age, 9.3 ± 1.6 years); and the control group (Group 3) comprised of 21 subjects, 11 girls and 10 boys (mean age, 9.8 ± 1.9 years). Treatment and control changes within the groups and the differences between the groups were analyzed statistically. Intra-group comparisons were evaluated using the non-parametric Wilcoxon"s test and intergroup changes were analyzed using the Kruskal-Wallis test. The statistical significance of intergroup differences was further assessed with the Mann-Whitney test for independent samples and applying Bonferroni"s correction (p < 0.016). Results: In group 1, SNB changes were less than the control. There were increases in SNA, ANB, SN-MP, A to N perp and Upper lip to E plane. In group 2, SNB, U1-NA (mm) U1-NA (o) and Pog to N perp (mm) changes were less than the control. There were increases in SNA, ANB, SN-MP, A to N perp and Upper lip to E plane. Conclusions: Modified facemask appliance can be used effectively in Class III patients with a retrognathic maxilla. Facemask therapies with expansion resulted in an anterior advancement and translation of maxilla without rotation; and the mandible moved downward and backward in both treatment groups. (Korean J Orthod 2010;40(6):432-443)

Properties of Synchronous Versus Metachronous Bilateral Breast Carcinoma with Long Time Follow Up

Eliyatkin, Nuket,Zengel, Baha,Yagci, Ayse,Comut, Erdem,Postaci, Hakan,Uslu, Adam,Aktas, Safiye Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

Background: Breast cancer is the most common cancer type among women with increasing incidence rates, improved prognosis and survival. According to the localization of the tumor, breast cancer is designated as unilateral (UBC) or bilateral (BBC). BBC can be classified as synchronous (SBBC) or metachronous (MBBC) based on the time interval between the diagnosis of the first and the secondary tumors. According to the guideline of WHO 2012, BBC is generally defined as SBBC when contralateral breast carcinoma is diagnosed within 3 months. The aim of this study was to compare the characteristics and patterns of metastasis of BBC patients with UBC. Materials and Methods: A cohort of 768 patients with breast cancer treated at the Turkish Ministry of Health-Izmir Bozyaka Research and Training Hospital between 1976 and 2012 were studied. Survival analysis was performed comparing UBC and BBC patients. In addition, evaluations were performed in patients with SBBC and MBBC sub-groups. We used a 3-months interval to distinguish metachronous from synchronous. Results: When clinical and histopathological parameters were statistically evaluated, ER status, event-free and overall survival were found to be significant between UBC and BBC patients. In comparison of SBBC and MBBC patients, age, histological type of tumor, event-free and overall survival were found to be significant. Conclusions: BBC cases were found to show worse prognosis than UBC cases. Among BBC, SBBC had the worst prognosis based on overall survival rates.

Vancomycin Loaded Gelatin Microspheres Containing Wet Spun Poly(ε-caprolactone) Fibers and Films for Osteomyelitis Treatment

Eda Ayse Aksoy,Betul Suyumbike Yagci,Gulseher Manap,Ipek Eroglu,Sukru Ozturk,Melike Ekizoglu,Kezban Ulubayram 한국섬유공학회 2019 Fibers and polymers Vol.20 No.11

In this study, it was aimed to develop drug eluting biodegradable and biocompatible bone supportive fibers andfilms, which can locally be applicable on the infected bone defect area for osteomyelitis treatment. For this purpose,vancomycin (Vm) loaded gelatin (G) microspheres were prepared and dispersed into poly(ε-caprolactone) (PCL) solutionand then the suspension was processed as films and fibers by solvent casting and wet spinning techniques, respectively. Themean particle size distribution and morphology of Vm loaded G microspheres were characterized by laser diffraction methodand scanning electron microscopy, respectively. In vitro Vm release profiles and release kinetics from microsphere, fiber andfilm formulations were investigated. In vitro biodegradation properties of fiber and film formulations were examined in bothhydrolytic and enzymatic media during 25 days period. The cytotoxicity of Vm eluting films and fibers were tested on L929cells by MTT assay. Presence of PCL in film and fiber formulations retarded the release of Vm from microspheres andprovided long term sustained release. Vm eluting films and fibers exhibited strong antibacterial properties againstStaphylococcus aureus and Staphylococcus epidermidis.