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Fuhui Cui,Junjie Wang1,Xiangdong Gan,Dawei Yu,Ilya Vladimirovich Okulov,Qinghua Tian,Xueyi Guo 대한금속ᆞ재료학회 2023 METALS AND MATERIALS International Vol.29 No.2
Liquid Mg is capable of quickly eroding the refractory Ni-based superalloy and selectively dissolve Ni, which opens up anew avenue for the recycling of superalloy scraps for comprehensive metal reclamation. This study aims at investigating theunderlining mechanism and kinetics of the selective dissolution of Ni from Inconel 718 (one type of Ni-based superalloy)with liquid Mg, by experimenting at 750, 800, and 850 °C for various amounts of time in an inert atmosphere. This selectivedissolution process is also known as liquid metal dealloying. Results show that a permeable dealloyed layer was formedresulting from the preferential dissolution of Ni over other metallic elements (e.g., Fe, Cr, Nb, Mo, and Ti). At the dealloyingforefront, the grain boundaries of the matrix γ phase were preferentially eroded by liquid Mg. The opposite concentrationgradients of Ni (4–9 wt%) and Mg (12–18 wt%) cross the dealloyed layer suggested their counter diffusion. A higher heatingtemperature substantially increased the dealloying rate.
Wang Jianle,Xia Dongdong,Lin Yan,Xu Wenbin,Wu Yaosen,Chen Jiaoxiang,Chu Junjie,Shen Panyang,Weng Sheji,Wang Xiangyang,Shen Lifeng,Fan Shunwu,Shen Shuying 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Low back pain, triggered by intervertebral disc degeneration (IVDD), is one of the most common causes of disability and financial expenditure worldwide. However, except for surgical interventions, effective medical treatment to prevent the progression of IVDD is lacking. This study aimed to investigate the effects of circKIF18A, a novel circRNA, on IVDD progression and to explore its underlying mechanism in IVDD. In this study, we found that oxidative stress was positively correlated with nucleus pulposus cell (NPC) senescence in IVDD and that circKIF18A was downregulated in IVDD and attenuated senescent phenotypes such as cell cycle arrest and extracellular matrix degradation in NPCs. Mechanistically, circKIF18A competitively suppressed ubiquitin-mediated proteasomal degradation of MCM7, and the protective effects of circKIF18A on NPCs were partially mediated by MCM7 under oxidative stress. Intradiscal injection of adenoviral circKIF18A ameliorated IVDD in a rat model. This study revealed that circKIF18A regulates NPC degeneration by stabilizing MCM7 and identified a novel signaling pathway, the circKIF18A-MCM7 axis, for anti-senescence molecular therapy in IVDD.
Wang Junjie,Yun Jinfeng,Lv Shijie,Wang Hongmei 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
39 accessions of sickle alfalfa (Medicago falcata L.) collected from different regions of China were evaluated for their tolerance to drought. Differences were observed among accessions in their reactions to drought and 8 good tolerant accessions at populations level and 18 excellent tolerant accessions at individual level were identified based on drought response index (DRI).
Structure and Electrical Performance of Na<sub>2</sub>C<sub>6</sub>O<sub>6</sub> under High Pressure
Wang, Xuan,Zhang, Peijie,Tang, Xingyu,Guan, Junjie,Lin, Xiaohuan,Wang, Yajie,Dong, Xiao,Yue, Binbin,Yan, Jinyuan,Li, Kuo,Zheng, Haiyan,Mao, Ho-kwang American Chemical Society 2019 The Journal of Physical Chemistry Part C Vol. No.
<P>Sodium rhodizonate (Na<SUB>2</SUB>C<SUB>6</SUB>O<SUB>6</SUB>) has very high theoretical capacity as a positive electrode material of sodium-ion batteries, but it still has problems such as low actual capacity and poor electronic/ionic conductivity. In order to improve its conductivity, we investigated its structure and electrical properties under high pressure. By performing in situ X-ray diffraction, Raman, infrared absorption, and alternating current impedance spectroscopy in the range of 0-30 GPa at room temperature, we observed a phase transition at ∼11 GPa, with the conductivity increasing by an order of magnitude. Above ∼20 GPa, Na<SUB>2</SUB>C<SUB>6</SUB>O<SUB>6</SUB> gradually amorphized. During the decompression process, the pressure regulation of the structure and properties of the material are reversible. Our study shows that applying external pressure is an effective tool to improve the conductivity of molecular battery materials. The investigation will help to obtain next-generation electrode materials.</P> [FIG OMISSION]</BR>
Optimal Target Reliability of Bridges Based on Minimum Life-Cycle Cost Consideration
Wang, Junjie,Lee, J-C Computational Structural Engineering Institute of 2002 Computational structural engineering Vol.2 No.1
Cost-effectiveness in design is considered for determining the target reliability of concrete bridges under seismic actions. This objective can be achieved based on the economic optimization of the expected life-cycle cost of a bridge, which includes initial cost, direct losses, and indirect losses of a bridge due to strong earthquakes over its lifetime. A separating factor is defined to consider the redundancy of a transportation network. The Park-Ang damage model is employed to define the damage of a bridge under seismic action, and a Monte Carlo method based on the DRAIN-2DX program is developed to assess the failure probability of a bridge. The results for an example bridge analyzed in this paper show that the optimal target failure probability depends on the traffic volume carried by the bridge and is between 1.0×10/sup -3/ to 3.0×10/sup -3/ over a life of 50 years.
Yong Wang,Zhi Lu,Ningnin Wang,Jianzhou Feng,Junjie Zhang,Lan Luan,Wei Zhao,Xiandong Zeng 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
Long non-coding RNAs (lncRNAs) play key roles in various malignant tumors, including colorectal cancer (CRC). Long non-coding RNA differentiation antagonizing non-protein coding RNA (DANCR) is overexpressed in CRC patients, but whether it affects CRC proliferation and metastasis via regulation of heat shock protein 27 (HSP27) remains unclear. In the present study, we found that DANCR was highly expressed and correlated with proliferation and metastasis in CRC. In addition, we demonstrated that DANCR and HSP27 were both targets of microRNA-577 (miR-577) and shared the same binding site. Furthermore, we revealed that DANCR promoted HSP27 expression and its mediation of proliferation/metastasis via miR-577 sponging. Finally, using an in vivo study, we confirmed that overexpression of DANCR promoted CRC tumor growth and liver metastasis. The present study demonstrated the function of DANCR in CRC and might provide a new target in the treatment of CRC.
Junjie Jiang,Housheng Zhang,Duo Jin,Ao Wang,Longhao Liu 전력전자학회 2024 JOURNAL OF POWER ELECTRONICS Vol.24 No.2
The existence of load disturbance can lead to the instability of permanent magnet synchronous motor (PMSM) speed control systems. Therefore, a non-singular fast terminal sliding mode control (NFTSMC) strategy based on a disturbance observer is proposed in this paper. First, a new exponential reaching law is presented to relate the rate of convergence to the state error and switching function, which achieves an improvement of the system convergence speed while reducing system jitter. At the same time, to eliminate system jitter, a new smooth saturation function is introduced in place of the symbolic function. Second, a non-singular fast terminal (NFT) sliding surface is generated by combining a nonlinear function with a linear funtion, which makes the state error converge rapidly at different stages. Finally, a disturbance observer is built to boost the robustness of the control system by observing the outside disturbance value and feeding it back to the speed controller. The dependability and effectiveness of the proposed control strategy are confirmed by simulation experiments with MATLAB.
Wang Haifei,Guan Xiaoying,Chen Guo,Gong Junjie,Yu Liang,Yuan Shijie,Zhu Zhida 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.1
Outer ring of bearing fit looseness fault is a common fault. Scratch often appears in the inner surface of pedestal. The fit looseness fault mechanism is not clear. For rotor-rolling bearing system with fit looseness fault between rotor-bearing outer ring and pedestal, a rotor coupling dynamic model that the interaction of bearing outer ring and pedestal are considered. This model is different from the universal rubbing model, where the directions of relative motion between rotor and stator are not considered. Numerical integration method is used to obtain the response of the system where the rotor is established by FEM and the bearing outer ring and pedestal are established by lumped mass model. Firstly, modal test results and simulation results were used to verify the correctness of this model. Secondly, the role of tightening torque between bearing outer ring and pedestal is considered, and the response characteristics of bearing and rotor are analyzed when fit looseness fault is considered. Finally, comparing the simulation results with test results, the waveform and spectrum are similar, which verifies the correctness of the fit looseness model. The fit looseness fault characteristics are that the acceleration after noise reduction shows periodic impact, up and down asymmetry, multiple frequencies appear. A method by increasing tightening torque is put forward to control the vibration caused by fit looseness fault.
Junji Wang,Caoyuan Ma,Chunxiao Li,Xinshang Zhu,Kang Zhao 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.10
A structural vulnerability analysis of China mine power grid, which considering the particular of topological structure and the increase gas power generation nodes, is proposed based on complex network theory. According to transmission capacity of weighted network model, this paper analyses the network characteristics, including degree distribution, clustering coefficient and average path length, to prove that the mine power grid is a scale -free network. The node importance, node betweenness, edge weight and edge betweenness are regarded as the index of identification and the remaining load capacity after attack is chosen as evaluation index to analyze the structural vulnerability of mine power grid to have a fault simulation of the mine power grid before and after adding gas power generation nodes. The results of fault simulation show that the model is in line with the actual situation of the China mine power grid, and can better identify and assess the vulnerability of the mine power grid.
Molecular Cloning and Expression of Grass Carp MyoD in Yeast Pichia pastoris
Wang, Lixin,Bai, Junjie,Luo, Jianren,Chen, Hong,Ye, Xing,Jian, Qing,Lao, Haihua Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.1
MyoD, expressed in skeletal muscle lineages of vertebrate embryo, is one of muscle-specific basic helix-loop-helix (bHLH) transcription factors, which plays a key role in the determination and differentiation of all skeletal muscle lineages. In this study, a cDNA of grass carp MyoD was cloned and characterized from total RNA of grass carp embryos by RT-PCR. The full-length cDNA of grass carp MyoD is 1597 bp. The cDNA sequence analysis reveals an open reading frame of 825 bp coding for a protein of 275 amino acids, which includes a bHLH domain composed of basic domain (1-84th amino acids) and HLH domain (98-142th amino acids), without signal peptide. Then the MyoD cDNA of grass carp was cloned to yeast expression vector pPICZ$\alpha$A and transformed into P. pastoris GS115 strain, the recombinant MyoD protein with a molecular weight of about 31KD was obtained after inducing for 2d with 0.5% methanol in pH 8.0 BMGY medium, and the maximum yield was about 250 mg/L in shaking-flask fermentation. The results were expected to benefit for further studies on the crystal structure and physiological function of fish MyoD.