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- 저자 : Tuna Filiz (검색결과 3 건)
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Hakan Tuna,Murat Birtane,Galip Ekuklu,Fikret Cermik,Filiz Tuna,Siranus Kokino 연세대학교의과대학 2008 Yonsei medical journal Vol.49 No.3
Purpose: Efforts for the early detection of bone loss and subsequent fracture risk by quantitative ultrasound (QUS), which is a non-invasive, radiation free, and cheaper method, seem rational to reduce the management costs. We aimed in this study to assess the probable correlation of speed of sound (SOS) values obtained by QUS with bone mineral density (BMD) as measured by the gold standard method, dual energy X-ray absorptiometry (DEXA), and to investigate the diagnostic value of QUS to define low BMD. Materials and Methods: One hundred twenty-two postmenopausal women having prior standard DEXA measurements were included in the study. Spine and proximal femur (neck, trochanter and Ward's triangle) BMD were assessed in a standard protocol by DEXA. The middle point of the right tibia was chosen for SOS measurement by tibial QUS. Results: The SOS values were observed to be significantly higher in the normal BMD (t score >-1) group at all measurement sites except for the lumbar region, when compared with the low BMD group (t score <-1). SOS was negatively correlated with age (r=-0.66) and month since menopause (r=-0.57). The sensitivity, specificity, and positive and negative predictive values for QUS t score to diagnose low BMD did not seem to be satisfactory at either of the measurement sites. Conclusion: Tibial SOS was correlated weakly with BMD values of femur and lumbar spine as measured by DEXA and its diagnostic value did not seem to be high for discriminating between normal and low BMD, at these sites.
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Antifungal Activity of the Honeybee Products Against Candida spp. and Trichosporon spp.
Ayşe Nedret Koç,Sibel Silici,Filiz Kasap,Hatice Tuna Hörmet-Öz,Hikmet Mavus-Buldu,Barış Derya Ercal 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.1
Honeybee products (honey, royal jelly, pollen, and propolis) were evaluated for their ability to inhibit the growth of 40 yeast strains of Candida albicans, Candida glabrata, Candida krusei, and Trichosporon spp. The broth microdilution method was used to assess the antifungal activity of honeybee products against yeasts. Fluconazole was selected as the antifungal control agent. Using the broth microdilution method, minimal inhibitory concentration ranges with regard to all isolates were 5–80% (vol/vol), 0.06–1μg/mL, 0.002–0.25μg/mL, 0.006–0.1μg/mL, and 0.02–96μg/mL for honey, royal jelly, pollen, propolis, and fluconazole, respectively. The antifungal activities of each product decreased in the following order: propolis >pollen>royal jelly>>honey. This study demonstrated that honeybee products, particularly propolis and pollen, can help to control some fluconazole-resistant fungal strains.
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A New Clinical Tool for Scoliosis Risk Analysis: Scoliosis Tele-Screening Test
Yılmaz Hurriyet Gursel,Büyükaslan Ahsen,Kuşvuran Aslihan,Turan Zeynep,Tuna Filiz,Tunc Hande,Özdoğan Sibel 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.4
Study Design: Methodological, observational clinical study.Purpose: This study aimed to develop a virtual screening test to detect scoliosis risk initially by parents without the need for medical visit during the coronavirus disease 2019 pandemic.Overview of Literature: The scoliosis screening program has been implemented to early detect scoliosis. Unfortunately, access to health professionals was limited during the pandemic. However, during this time, interest in telemedicine has increased remarkably. Recently, mobile applications related to postural analysis were developed, but none permits evaluation by parents.Methods: Researchers developed the Scoliosis Tele-Screening Test (STS-Test), which included drawing-based images of body asymmetries, to assess the scoliosis-associated risk factors. The STS-Test was shared on social networks, allowing the parents to evaluate their children. After test completion, the risk score was generated automatically, and children with medium and high risks were then advised for medical consultation for further evaluation. The test accuracy and consistency between the clinician and parents were also analyzed.Results: Of the 865 tested children, 358 (41.4%) consulted clinicians to confirm their STS-Test results. Scoliosis was then confirmed in 91 children (25.4%). The parents were able to detect asymmetry in 50% of the lumbar/thoracolumbar curvatures and 82% of the thoracic curvatures. In addition, the forward bend test revealed favorable agreement between parents and clinicians (<i>r</i> =0.809, <i>p</i><0.0005). Internal consistency of the esthetic deformities domain in the STS-Test was also excellent (α=0.901). This tool was 94.97% accurate, 83.51% sensitive, and 98.87% specific.Conclusions: The STS-Test is a new parent-friendly, virtual, cost-effective, result-oriented, and reliable tool for scoliosis screening. It allows parents to actively participate in the early detection of scoliosis by screening their children for the risk of scoliosis periodically without the need to visit the health institution.
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