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      • Simple replication methods for producing nanoslits in thermoplastics and the transport dynamics of double-stranded DNA through these slits

        Chantiwas, Rattikan,Hupert, Mateusz L.,Pullagurla, Swathi R.,Balamurugan, Subramanian,Tamarit-Ló,pez, Jesú,s,Park, Sunggook,Datta, Proyag,Goettert, Jost,Cho, Yoon-Kyoung,Soper, Steven A. Royal Society of Chemistry 2010 Lab on a chip Vol.10 No.23

        <P>Mixed-scale nano- and microfluidic networks were fabricated in thermoplastics using simple and robust methods that did not require the use of sophisticated equipment to produce the nanostructures. High-precision micromilling (HPMM) and photolithography were used to generate mixed-scale molding tools that were subsequently used for producing fluidic networks into thermoplastics such as poly(methyl methacrylate), PMMA, cyclic olefin copolymer, COC, and polycarbonate, PC. Nanoslit arrays were imprinted into the polymer using a nanoimprinting tool, which was composed of an optical mask with patterns that were 2–7 µm in width and a depth defined by the Cr layer (100 nm), which was deposited onto glass. The device also contained a microchannel network that was hot embossed into the polymer substrate using a metal molding tool prepared <I>via</I> HPMM. The mixed-scale device could also be used as a master to produce a polymer stamp, which was made from polydimethylsiloxane, PDMS, and used to generate the mixed-scale fluidic network in a single step. Thermal fusion bonding of the cover plate to the substrate at a temperature below their respective <I>T</I><SUB>g</SUB> was accomplished by oxygen plasma treatment of both the substrate and cover plate, which significantly reduced thermally induced structural deformation during assembly: ∼6% for PMMA and ∼9% for COC nanoslits. The electrokinetic transport properties of double-stranded DNA (dsDNA) through the polymeric nanoslits (PMMA and COC) were carried out. In these polymer devices, the dsDNA demonstrated a field-dependent electrophoretic mobility with intermittent transport dynamics. DNA mobilities were found to be 8.2 ± 0.7 × 10<SUP>−4</SUP> cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> and 7.6 ± 0.6 × 10<SUP>−4</SUP> cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> for PMMA and COC, respectively, at a field strength of 25 V cm<SUP>−1</SUP>. The extension factors for λ-DNA were 0.46 in PMMA and 0.53 in COC for the nanoslits (2–6% standard deviation).</P> <P>Graphic Abstract</P><P>Thermoplastic nanoslits were replicated from a simple molding tool and consisted of mixed-scale structures with successful DNA translocation through the slits demonstrated. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0lc00096e'> </P>

      • KCI등재

        Iron doped vanadium sulfide anemone like nanorod structure for electrochemical water oxidation

        Swathi S.,Yuvakkumar R.,Ravi G.,S.I. Hong,Babu E. Sunil,Velauthapillai Dhayalan,Algarni Tahani Saad,Al-Mohaimeed Amal M. 한국물리학회 2021 Current Applied Physics Vol.21 No.-

        Bare and Fe doped vanadium sulfide nanorods was synthesized by employing sol-gel method. The obtained (011) plane revealed and confirmed the orthorhombic phase of vanadium sulfide (VS). Fe doped vanadium sulfide anemone like nanorods structure were demonstrated by morphological evolution employing SEM studies. FTIR studies confirmed the vibrational frequencies of the prepared samples and identify the functional groups. Raman technique is also used to observe the vibrational modes of molecules and PL revealed the prepared samples optical-electronic nature. Additionally, electrochemical studies such as cyclic voltammetry (CV), linear sweep voltammetry (LSV), electrochemical impedance spectroscopy (EIS) and chronoampherometry (CA) was recorded for determination of specific capacitance, current density and stability. High doped vanadium sulfide has elevated 1372 F/g specific capacitance at 385 mA/g current density attained from CV and LSV curves at 10 mV/s and it has proven the excellent OER activity.

      • KCI등재

        Cancer targeting potential of bioinspired chain like magnetite (Fe3O4) nanostructures

        S. Swathi,Fuad Ameen,G. Ravi,R. Yuvakkumar,S.I. Hong,Dhayalan Velauthapillai,Muneera D.F. AlKahtani,M. Thambidurai,Cuong Dang 한국물리학회 2020 Current Applied Physics Vol.20 No.8

        Iron is significant, earth abundant and inexpensive materials in everyday use. Non toxicity and clean manufacturing process is still a challenging role in scientific world. The chain like Fe3O4 nanostructures were synthesized using the mixtures such as iron nitrate and Rambutan. Magnetite Fe3O4 was verified using X-ray powder diffraction (XRD). Metal oxide (Fe–O) and A1g and Eg phonon modes are substantiated employing Fouriertransform infrared spectroscopy (FTIR) and Raman spectra. A product chemical state was investigated by high resolution X-ray photoelectron spectroscopy (XPS) spectra. Chain like morphology and polycrystalline nature is attributed by transmission electron microscopy (TEM) analysis. Weight loss activity was revealed through thermogravimetric analysis (TGA) analysis. In application studies, higher concentration of Fe3O4 nanostructures was more effective than the low concentration. Moreover, cytotoxicity effects and cell viability on human cancer cell lines were observed and tested for cancer treatment.

      • KCI등재

        A new genus in the tribe Acidoxanthini (Diptera: Tephritidae: Trypetinae) from India, with a discussion of its phylogenetic relationships

        David Karamankodu Jacob,Hancock David Lawrence,Han Ho-Yeon,Gracy Gandhi R,Sachin K.,Swathi R.S. 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.4

        Gibbifronta pavoniae David, Hancock and Han, gen. et sp. nov., is described from India. The current status of the subtribe Acidoxanthina is scrutinized based on both morphological characters and DNA barcoding analysis, and this taxon is formally proposed as the tribe Acidoxanthini within the subfamily Trypetinae in order to accom modate the genera Gibbifronta, Acidoxantha Hendel, Craspedoxanthitea Hardy and Acidoxanthopsis Hering. We found that the members of the Acidoxanthini possess a unique characteristic within the family Tephritidae, the short and broadly truncate lateral surstylus with reduced prensisetae and 1–3 pairs of strong dorsal setae on epandrium. Even though comparable information is not available for Acidoxanthopsis, it is retained in Acid oxanthini. Gibbifronta is distinguished from other genera of the tribe by the presence of a high gena and prominent hump-like projection on the frons. Phylogenetic analysis based on DNA barcodes revealed that Gib bifronta is closely related to Acidoxantha and support its placement in Acidoxanthini. COI sequences of Gibbifronta pavoniae, Nitrariomyia lukjanovitshi Rohdendorf, Acidoxantha galibeedu David and Ramani and an undescribed Acidoxantha species have been obtained and reported. A key to the genera of Acidoxanthini is also provided. http://zoobank.org/100D010D-21D3-4F0B-B38E-1F72DC8E9BF3.

      • KCI등재

        Taxonomic notes on fruit flies of tribes Schistopterini and Eutretini (Diptera: Tephritidae: Tephritinae) in India, with description of a new species of Rhabdochaeta de Meijere

        David Karamankodu Jacob,Hancock David Lawrence,Sachin K.,Gracy Gandhi R,Swathi R.S. 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.1

        Rhabdochaeta nigroapicalis David, Hancock and Sachin, sp. n., is described from Assam, NE India. A key to all species of Schistopterini and Eutretini recorded from India is provided and taxonomic notes on previously described species are included. DNA barcode sequences of Calloptera asteria (Schiner), Rhabdochaeta pulchella de Meijere, Rhabdochaeta nigroapicalis David, Hancock and Sachin, sp. n. and Rhochmopterum venustum (de Meijere) were obtained and reported. Phylogenetic analysis using 62 mtCOI sequences of Tephritinae revealed Schis topterini to be a monophyletic group and the new species closely related to Rhabdochaeta pulchella, justifying its placement in Rhabdochaeta de Meijere. http://zoobank.org/A97337B3-E2BD-460D-BA62-6D3D4A1A60A2

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