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Serological study of canine H3N2 influenza virus in dogs in 2016 - 2017, Korea
Seyeon Park(Seyeon Park),In-Ohk Ouh(In-Ohk Ouh),Ju-Yeon Lee(Ju-Yeon Lee),Min-Su Cho(Min-Su Cho),Byeong Sul Kang(Byeong Sul Kang),Soo dong Cho(Soo dong Cho),Jae Young Song(Jae Young Song) 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Isolation and phylogenetic analysis of swine influenza A viruses (H1N2) in Korea in 2016 - 2017
Seyeon Park(Seyeon Park),In-Ohk Ouh(In-Ohk Ouh),Ju-Yeon Lee(Ju-Yeon Lee),Min-Su Cho(Min-Su Cho),Byeong Sul Kang(Byeong Sul Kang),Soo dong Cho(Soo dong Cho),Eun-Ju Kim(Eun-Ju Kim),Yeun-Kyung Shin(Yeun- 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Serological study of swine influenza A viruses in pig population in 2016 - 2017, Korea
Seyeon Park(Seyeon Park),In-Ohk Ouh(In-Ohk Ouh),Ju-Yeon Lee(Ju-Yeon Lee),Min-Su Cho(Min-Su Cho),Byeong Sul Kang(Byeong Sul Kang),Soo dong Cho(Soo dong Cho),Eun-Ju Kim(Eun-Ju Kim),Yeun-Kyung Shin(Yeun- 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Fingertip Force and Muscle Activation Patterns at Varying grasp Objects
Suji Park(Suji Park),Juhyun Park(Juhyun Park),Seyeon Oh(Seyeon Oh),Chaeyeon Heo(Chaeyeon Heo),Sieun Ho(Sieun Ho),Seonhong Hwang(Seonhong Hwang) 호서대학교 기초과학연구소 2022 기초과학연구 논문집 Vol.30 No.1
In this study, we tried to collect and analyze the kinetic and neurological information such as finger-tip forces and EMG for several representative (the most commonly used) grasp movements to explore their force and muscle activation patterns based on the newly defined grasp taxonomy. Ten able-bodied (five males, five females) volunteered to participate and they performed five different grasp tasks: holding a bottle (Bottle), turning a doorknob (Knob), cutting with a knife (Knife), brushing with a toothbrush (Toothbrush), holding a thick book (Book) after we attached five force sensitive resistor (FSR) sensors on the tip of fingers and four surface electromyogram (sEMG) electrodes on the lower arm of the subject’s dominant hand. Root Mean Square (RMS) and Mean Absolute Value (MAV) from the mean maximum values of sEMG(%) and fingertip force(kgf) of all ten subjects were extracted as features. The classification from the feature dataset using convolutional neural network (CNN) was applied and analyzed the results of accuracy and repeatability. The mean maximum values of EMG and fingertip forces during five different grasp tasks, and the MAV and RMS which were extracted features from the above were compared with task pairs. They showed significant differences in comparison of four pairs of tasks which were Bottle and Knife (p = 0.005 in both MAV and RMS), Bottle and Toothbrush (p = 0.005in both MAV and RMS), Bottle and Book (p = 0.013 in both MAV and RMS), Knob and Toothbrush (p = 0.047 in MAV and p = 0.028 in RMS). The classification accuracy of the Bottle grasp task was the largest at 60% (true positive predictive rate is 60% and false postive rate is 40%), while the other tasks showed an 30-40% of accuracy. Repeatability was 60% in the Bottle task and 50% in the Knob task, and those of the other tasks were ranged 30-40%. Overall, it is believed that the small number of samples in the study is the main reason of the low accuracy and repeatability of the classification. A total of nine variables (four sEMG and five forces) showed different significances in paired mean comparisons for five grasp tasks (graspping a bottle, turning a doorknob, cutting with a knife, brushing teeth with a toothbrush, holding a thick book). A comparison of the reduced variable from feature extraction also showed different classification accuracy for five grasp tasks.
Scrambling in Korean Parasitic Gap Constructions and its Cross-linguistic Implications
Seyeon Park(박세연) 한국언어학회 2018 언어 Vol.43 No.1
Parasitic gap constructions have been observed to fall into two subtypes across languages: adjunct clause type and subject clause type. Previous research on Korean parasitic gaps has either assumed that both subtypes exist in Korean as in English, or analyzed the movement properties of scrambling as in Japanese. This paper is about the argument that the previous studies have not considered the specific properties of the clausal boundaries and scrambling patterns in Korean. In this paper, the distinct properties of adjunct clauses and subject clauses in Korean were examined to see how their differences structurally affect the pattern of scrambling. I propose that the subject clause type of the parasitic gap construction exists in Korean, but what has been analyzed as the adjunct clause in the literature should be analyzed as containing a null pronoun. This claim is empirically supported by comparing the properties of a parasitic gap with those of a null pronoun. On the basis of the observed pattern in Korean parasitic gap constructions, I discuss its cross-linguistic implications on the parasitic gap hierarchy proposed by Culicover (2017).
Proteome profile changes in SH‐SY5y neuronal cells after treatment with neurotrophic factors
Park, Seyeon,Lee, Joomin Wiley Subscription Services, Inc., A Wiley Company 2011 Journal of cellular biochemistry Vol.112 No.12
<P><B>Abstract</B></P><P>Artemin, one of glial cell line‐derived neurotrophic factors (GDNFs) supports sensory neuron. Although a role of artemin and GDNF as neurite outgrowth regulators in early neuron development has been suggested, the immediate effects of artemin and GDNF on neuronal cells have not been elucidated. Here, we investigated artemin and GDNF actions on the neuronal cell proteome. To identify immediate‐early protein changes by artemin and GDNF in neuronal cells, we used a differential proteomics approach in SH‐SY5y human neuronal cells treated with artemin or GDNF for 1 h. Eleven proteins that changed after both artemin and GDNF treatment were identified using two‐dimensional gel electrophoresis and matrix‐assisted laser desorption ionization time‐of‐flight tandem mass spectroscopy. The calcium ion‐binding chaperone calreticulin and calcium/calmodulin‐binding nuclear matrix protein matrin 3 showed common quantitative differences after both artemin and GDNF treatment. Cytoskeletal proteins also showed quantitative profile differences, which are functionally relevant to cytoskeletal rearrangement leading to the neurite elongation in neurons. These protein changes were detected in neuronal cells without accompanying changes in mRNA levels. These results suggest that immediate changes induced by artemin and GDNF are related to cytoskeletal protein level changes without transcriptional regulation. J. Cell. Biochem. 112: 3845–3855, 2011. © 2011 Wiley Periodicals, Inc.</P>
Cold exposure lowers energy expenditure at the cellular level.
Park, Seyeon,Chun, Sohyun,Kim, Danuh Published for the International Federation for Cel 2013 Cell biology international Vol.37 No.6
<P>Mitochondrial function is intimately involved in various metabolic processes and is therefore essential to maintain cell viability. Of particular importance is the fact that mitochondrial membrane potential (δψm ) is coupled with oxidative phosphorylation to drive adenosine triphosphate (ATP) synthesis. We have examined the effects of cold temperature stress on δψm and the role of cold temperature receptor expression on δψm . Human bronchial endothelial cell line, BEAS-2B, and human embryonic kidney, HEK293, cell line were transfected with the gene for cold temperature responsive receptor protein TRPM8 or TRPA1, and exposed to cold temperature. δψm was monitored using 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazoyl carbocyanine iodide derivative (JC-10), a δψm probe. While cold temperatures significantly increased δψm and mitochondrial ATP levels in cells transfected with temperature responsive receptor TRPM8 or TRPA1, no change was noted in wild-type cells. Moreover, the change in δψm and ATP level was a dynamic process. δψm was raised to peak levels within 10 min of cold exposure, followed by a return to baseline levels at 30 min. Our findings suggest that cold temperature exposure increased mitochondrial δψm via a mechanism involving cold temperature receptors.</P>
Proteomic analysis to identify early molecular targets of pregabalin in C6 glial cells.
Park, Seyeon,Lee, Joomin Published for the International Federation for Cel 2010 Cell biology international Vol.34 No.1
<P>Pregabalin is a lipophilic amino acid derivative of gamma-amino butyric acid that displays anticonvulsant and analgesic activities against neuropathic pain. Although a role for glial cells as an important player in pain control and also as a new target for pain medicine has been suggested, the effect of pregabalin on glial cells has not been elucidated. In the present study, we have investigated the action of pregabalin on the glial cell proteome. To identify immediate early protein targets of pregabalin in glial cells, a differential proteomics approach in C6 rat glioma cells treated with pregabalin was used. Seven proteins that sensitively reacted to pregabalin treatment were identified using two-dimensional gel electrophoresis and MALDI-TOF-MS (matrix-assisted laser-desorption ionization-time-of-flight MS). The calcium-ion-binding chaperone, calreticulin, and the oxidative response protein, DJ-1, were up-regulated after pregabalin treatment. Hsp (heat-shock protein)-90-beta, cytoskeleton protein actin and myosin also showed quantitative expression profile differences. Functionally relevant to the proteome result, immediate actin depolymerization was observed after treatment with pregabalin. These results suggest a previously undefined role of pregabalin in the regulation of chaperone activity and cytoskeleton remodelling in glial cells.</P>