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표정인식을 위한 PCA와 템플릿 정합을 사용한 얼굴 요소 추출
우효정, 이슬기, 김동우, 류성필, 안재형 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2
This paper proposed an extracting algorithm of human facial components for the recognition of facial expressions. First face image is acquired using the Haar-like feature mask from an input image. The face image is divided into two images. One is the upper image including eye and eyebrow. The other is the lower image including mouth and jaw. The extraction of facial components, such as eye and mouth, begins getting eye image and mouth image. Then eigenfaces are produced by the PCA training process with learning images. An eigeneye and an eigenmouth are produced from eigenfaces. Result eye image is obtained by template matching the upper image with the eigeneye, and the mouth image is obtained by template matching the lower image with the eigenmouth. The simulation results show that the proposed method has superior extraction ratio than previous method.
( Dam Kim ),( Soo-kyung Cho ),( Seoung Wan Nam ),( Hyuk Hee Kwon ),( Sun-young Jung ),( Chan Hong Jeon ),( Seul Gi Im ),( Dalho Kim ),( Eun Jin Jang ),( Yoon-kyoung Sung ) 대한류마티스학회 2017 대한류마티스학회지 Vol.24 No.5
Objective. To estimate the cardiovascular (CV) and gastrointestinal (GI) risks of etoricoxib in the treatment of osteoarthritis (OA) compared to a placebo and other non-steroidal anti-inflammatory drugs (NSAIDs). Methods. A systematic review of randomized, controlled trials (RCTs) of etoricoxib were performed. Bayesian network meta-analysis was used over a duration of 12 weeks. The incidence of CV and GI events for a duration ≥26 weeks were also tabulated and presented using descriptive statistics. Results. From this search, 10 studies were identified. Of these, 6 and 5 RCTs that measured the CV and GI events at 12 weeks were included in meta-analysis. They showed that etoricoxib did not increase the CV events compared to the placebo or NSAIDs during the 12 week period (odds ratio [OR]=0.59 compared to celecoxib, OR=0.89 with ibuprofen, OR=0.70 with placebo, and OR=2.16 with naproxen). The risk of GI events was comparable to that of most comparators, with the exception of naproxen, which had a significantly lower risk of GI events (OR=0.18) during the 12 week period. For a duration ≥26 weeks, the incidence of CV and GI events with etoricoxib increased with increasing duration. Conclusion. Etoricoxib is an alternative short-term treatment option for OA, showing comparable CV and GI complications to other NSAIDs. Nevertheless, further studies will be needed to elucidate the long-term safety of etoricoxib in the treatment of OA. (J Rheum Dis 2017;24:293-302)
Obesity induced by high fat diet in Rhomboid family member 2 (Rhbdf2) KO mice
Sung-Jun Kim(Sung-Jun Kim),Seul Gi Park(Seul Gi Park),Young-Sub Byun(Young-Sub Byun),Eun-Kyoung Kim(Eun-Kyoung Kim),Sang-Mi Cho(Sang-Mi Cho),Harim Kim(Harim Kim),Young-Suk Won(Young-Suk Won),Hyoung-Ch 한국예방수의학회 2017 한국예방수의학회 학술대회자료집 Vol.2017 No.-
Persistence of Genetically Modified Potatoes in the Field
Kim, Chang-Gi,Kim, Do-Young,Moon, Ye-Seul,Kim, Hyo-Jeong,Kim, Dae-In,Chun, Young-Jin,Park, Kee-Woong,Jeong, Soon-Chun,Kim, Soo-Young,Kim, Hwan-Mook 한국식물학회 2010 Journal of Plant Biology Vol.53 No.6
Volunteers from genetically modified (GM) potatoes may pose an environmental problemif allowed to grow in the field after the annual crop is harvested. We tested whether they are more likely to produce volunteers than non-GM potatoes. Specifically, we compared the number of volunteers, number of tubers per plant, tuber size, and their vertical distribution in the soil. More volunteer plants came from non-GM potatoes than from GM potatoes, but the number and size of tubers were similar between the two. Vertical distribution of the tubers differed significantly, with most non-GM tubers being found in shallower soil (<2 cm deep). Our results suggest that spontaneous GM volunteers may emerge and produce tubers to a degree similar to that of the non-GM plants. No viable volunteers emerged from GM tubers in the next growing season, probably deterred by winter frost and a period of low soil temperatures (below $-2^{\circ}C$) at our study site. However, in regions with warmer climates, such GM volunteers may survive Winter and produce more plants the following year.
Kim, Kwang-Youn,Park, Kwang-Il,Lee, Seul Gi,Baek, Su Youn,Lee, Eun Hye,Kim, Sang Chan,Kim, Sang-Hun,Park, Sul-Gi,Yu, Sun-Nyoung,Oh, Tae Woo,Kim, Joung-Hee,Kim, Keuk-Jun,Ahn, Soon-Cheol,Kim, Young Woo Elsevier 2018 Chemico-biological interactions Vol.294 No.-
<P><B>Abstract</B></P> <P>Deoxypodophyllotoxin (DPT) is a naturally occurring flavolignan in <I>Anthriscus sylvestris</I> known as cow parsley or wild chervil, and has been reported to have inhibitory effects against several pathological processes including cancer, inflammation and infection. Here, we report the effects of DPT in the fatty liver induced by high fat diet <I>in vivo</I> as well as its regulatory mechanism related with the transcription factor for lipogenic genes such as sterol regulatory element binding protein-1c (SREBP-1c) <I>in vitro</I>. C57BL/6 mice were fed high fat diet for 10 weeks and also orally administrated with DPT for additional 4 weeks. 5 and 10 mg/kg of DPT decreased lipid accumulation in the liver induced by high fat diet, as indicated by histological parameters such as Oil Red O staining and hematoxylin & eosin as well as the contents of hepatic triglyceride and cholesterol. In hepatocytes, DPT inhibited the liver X receptor α-mediated SREBP-1c induction and expression of the lipogenic genes, including fatty acid synthase, acetyl-CoA carboxylase and stearoyl-CoA desaturase-1. Moreover, DPT induced AMP-activated protein kinase (AMPK) activation, which has been known to inhibit the expression of SREBP-1c in hepatocyte. Also this compound restored the dysregulation of AMPK and SREBP-1c induced by high fat diet in mice. In conclusion, we demonstrated that DPT significantly inhibited fatty liver by adjusting lipid metabolism coordinated with AMPK activation and SREBP-1c inhibition.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Deoxypodophyllotoxin (DPT), a chemopreventive flavolignan, inhibited diet-induced fatty liver. </LI> <LI> DPT inhibited the LXR-α-mediated sterol regulatory element binding protein (SREBP)-1c. </LI> <LI> DPT blocked the expression of <I>de novo</I> lipogenic genes including FAS and ACC. </LI> <LI> DPT activated AMPK related with SREBP-1c inhibition. </LI> <LI> DPT might be a pharmaceutical candidate for hepatic steatosis. </LI> </UL> </P>
Seul Gi Baek(Seul Gi Baek),Jin Ju Park(Jin Ju Park),Sosoo Kim(Sosoo Kim),Mi-Jeong Lee(Mi-Jeong Lee),Ji-Seon Paek(Ji-Seon Paek),Jangnam Choi(Jangnam Choi),Ja Yeong Jang(Ja Yeong Jang),Jeomsoon Kim(Jeom 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.6
Fusarium head blight (FHB) is one of the most serious diseases in barley and wheat, as it is usually accompanied by the production of harmful mycotoxins in the grains. To identify FHB-resistant breeding resources, we evaluated 60 elite germplasm accessions of barley (24) and wheat (36) for FHB and mycotoxin accumulation. Assessments were performed in a greenhouse and five heads per accession were inoculated with both Fusarium asiaticum (Fa73, nivalenol producer) and F. graminearum (Fg39, deoxynivalenol producer) strains. While the accessions varied in disease severity and mycotoxin production, four wheat and one barley showed <20% FHB severity repeatedly by both strains. Mycotoxin levels in these accessions ranged up to 3.9 mg/ kg. FHB severity was generally higher in barley than in wheat, and Fa73 was more aggressive in both crops than Fg39. Fg39 itself, however, was more aggressive toward wheat and produced more mycotoxin in wheat than in barley. FHB severity by Fa73 and Fg39 were moderately correlated in both crops (r = 0.57/0.60 in barley and 0.42/0.58 in wheat). FHB severity and toxin production were also correlated in both crops, with a stronger correlation for Fa73 (r = 0.42/0.82 in barley, 0.70 in wheat) than for Fg39.
Effect of Ovarian Extract on Oocyte Maturation and Early Embryonic Development in Pigs
Seul-Gi Yang(Seul-Gi Yang),Jae-Hun Choi(Jae-Hun Choi),Young-Seo Jo(Young-Seo Jo),Ye-Won Kim(Ye-Won Kim),Dong-Mok Lee(Dong-Mok Lee),Hyo-Jin Park(Hyo-Jin Park),Deog-Bon Koo(Deog-Bon Koo) 한국동물보건학회 2022 한국동물보건학회지 Vol.1 No.2
Various factors in the ovary are known to regulate oocyte maturation and hormone secretory functions; however, the effect of ovarian extract (OE) on oocyte maturation and embryonic development in pigs remains unknown. In this study, we first evaluated whether OE supplementation in the in vitro maturation (IVM) medium alters the oocyte maturation capacity by affecting glucose/amino acid metabolites, meiotic maturation, cumulus cell (CC) expansion, and antioxidants. Various OE concentrations (50, 100, 200, 500, and 5000 μg/mL) were included in the IVM medium. Only the oocytes treated with 100 μg/mL OE exhibited an improved meiotic maturation rate when compared with that of the other groups (non-treated group, 78.6 ± 3.0% vs. 100 μg/mL OE-treated group, 81.6 ± 4.3%); however, the difference was not significant. To observe the changes in glucose and amino acid metabolism in the OE-treated oocytes, we measured the amounts of diverse constituents (glucose, lactate, glutamine, and ammonia) in the IVM medium containing OE. Lactate and ammonia levels in the OE-treated group after 44 h of IVM were higher (p < 0.01) than those in the non-treated group. In addition, the expression of the CC expansion factors (Has2 and Tnfaip6) significantly increased (p < 0.05), whereas the mRNA expression levels of antioxidative enzymes (Sod1, Cat, and Gpx1) significantly diminished (p < 0.05) in the OE-treated group. Moreover, mature oocytes treated with 100 μg/mL OE demonstrated increased subsequent embryonic development rates after 144 h of IVM. Thus, the addition of OE in IVM mediums may improve oocyte maturation capacity which could enhance antioxidative enzyme activation, energy metabolism, and expression of the CC expansion factors in porcine oocytes.
Won Gi Kim,Seul Ah Lee,Sung Min Moon,Jin-Soo Kim,Su-Gwan Kim,Yong Kook Shin,Do Kyung Kim,Chun Sung Kim 대한구강생물학회 2016 International Journal of Oral Biology Vol.41 No.4
Anthricin (Deoxypodophyllotoxin), a naturally occurring flavolignan, has well known anti-cancer properties in several cancer cells, such as prostate cancer, cervical carcinoma and pancreatic cancer. However, the effects of Anthricin are currently unknown in oral cancer. We examined the anticancer effect and mechanism of action of Anthricin in human FaDu hypopharyngeal squamous carcinoma cells. Our data showed that Anthricin inhibits cell viability in a dose- and time-dependent manner (IC50 50 nM) in the MTT assay and Live & Dead assay. In addition, Anthricin treated FaDu cells showed marked apoptosis by DAPI stain and FACS. Furthermore, Anthricin activates anti-apoptotic factors such as caspase-3, -9 and poly (ADP-ribose) polymerase (PARP), suggesting that caspase-mediated pathways are involved in Anthricin- induced apoptosis. Anthricin treatment also leads to accumulation of the pro-apoptotic factor Bax, followed by inhibition of cell growth. Taken together, these results indicate that Anthricn-induced cell death of human FaDu hypopharyngeal squamous carcinoma cells is mediated by mitochondrial-dependent apoptotic pathway. In summary, our findings provide a framework for further exploration on Anthricin as a novel chemotherapeutic drug for human oral cancer.
김슬기 ( Seul-gi Kim ),김민재 ( Min-jae Kim ),박기현 ( Gi-hyun Park ),이유용 ( Yu-yong Lee ),허웅 ( Heo Woong ),김종희 ( Jong-hee Kim ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.2
본 논문에서는 Kinect 장비를 이용하여 모션캡쳐를 할 수 있는 툴을 제작하여 제공한다. 자신이 캡쳐한 모션 데이터를 Web상에 공유하여 다른 사용자들이 볼 수 있게 한다. 궁극적인 목표로는 보급형 모션캡쳐장비 Kinect 사용한다면 간단하고 비교적 저렴하게 모션캡쳐를 사용할 수 있을 것이며, 모션캡쳐라는 생소함을 해소시키고자 함에 목표를 두었다.
Kim, Jun Beom,Lee, Seul Gi,Choi, Si-Young,Kim, Jaekook,Kim, Sang Ouk Elsevier 2019 CERAMICS INTERNATIONAL Vol.45 No.14
<P><B>Abstract</B></P> <P>Br-doped Li<SUB>4</SUB>Ti<SUB>5</SUB>O<SUB>12-<I>x</I> </SUB>Br<SUB> <I>x</I> </SUB> (“<I>x</I>” = 0, 0.1, 0.3, 0.5 and 0.7) anode materials were synthesized by a conventional solid-state reaction technique using precursors of Li<SUB>2</SUB>CO<SUB>3</SUB>, TiO<SUB>2</SUB> and LiBr, and the doping behavior and related electrochemical properties of these materials were studied. In our investigation, quantitative instrumental analyses revealed that most of the Br ions are situated on the surfaces/interfaces of agglomerated particles rather than in the bulk lattice. Narrow conduction paths of electron and Li-ion were, thus, formed on their surfaces/interfaces. During charging/discharging process, the presence of these narrow surface electrical conduits increased the rate-capability of the LTOBr samples. The LTOBr0.5 sample showed the highest capacity of 125 mAh/g at 1C compared to 115 mAh/g for pure LTO. A highly Br-doped sample (LTOBr0.7), however, showed a slight reduction in capacity. This was explained with the formation of fine precipitations (Br-containing second phase) on the surfaces of the LTO particles due to high Br addition.</P>