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Kenichi SATO 이화여자대학교 이화인문과학원 2016 탈경계인문학 Vol.9 No.1
This essay is an attempt to uncover the nature of the interface between the literary and the scientific in a fictional discourse. In so doing, it focuses on an anecdote in Charles Brockden Brown’s second novel Ormon; or, The Secret Witness (1799), in which the father of the novel’s heroine Constantia, Stephen Dudley, loses his sight but recovers it soon. The paper points out that this most curious, though unexplored, event is interlinked with various discourses that were bred in the Enlightenment period. Almost all of the critics have long ignored the fact that Dudley’s blindness has a distinct cause: a cataract. First, the paper tries to show, based on pathology, that the opening events in the novel and the progress of a cataract in Dudley’s eyes are paralleled. Second, it discusses the peculiar feature of the anecdote: the operation on the cataract. According to contemporary sources, there were two methods of cataract operation — depression and extraction — available in the Early Republic. Examination of these sources and Brown’s description proves that the method described in the novel is extraction, the advanced medical technology of the age, which can radically cure the blindness caused by cataracts. This is notable because Ormond, who helps remove Dudley’s cataract by calling a doctor, could be the object of removal in view of the US political situation. Ormond, who is a member of Illuminati, a secret society bred in the Enlightenment, has enough reason to be the “evil” that should be expelled immediately from the United States due to the enforcement of Alien Laws in 1799. Therefore, the fact that the person who should be removed helps remove a cataract critiques the Federalist policy. Thus, the two frameworks of reference — medical treatment and political thought — encounter at an anecdote in Ormond, which successfully contrives the interface between the literary and the scientific with a political resonance.
Novel Pathogenetic Mechanism in a Clinical Isolate of Yersinia enterocolitica KU14
Sato Yoshinori,Kaneko Kenichi,Sasahara Takeshi,Inoue Matsuhisa The Microbiological Society of Korea 2006 The journal of microbiology Vol.44 No.1
Yersinia enterocolitica induces a broad range of gastrointestinal syndromes, including acute enteritis. We previously reported that the clinical isolate, Y. enterocolitica KU14, which lacks pYV, was still capable of causing clinical infection. The present study demonstrated that KU14 did not trigger the death of macrophages in vitro, unlike WA-314 (ATCC51871, which harbors the pYV virulence plasmid). However, the intracellular growth of KU14 in the macrophages was greater than that of WA-C (ATCC51872, a non-plasmid harboring the derivative pYV plasmid). Treatment with a cholesterol-binding drug $(\beta-cyclodextrin)$ that affected lipid rafts resulted in a dramatic reduction in the inracellular growth of KU14. These data clearly indicate that the enhanced inracellular growth of KU14 is related to lipid raft-mediated infection.
Sato, Masayuki,Wakamatsu, Hiroki,Arai, Masayuki,Ichino, Kenichi,Iwasaki, Kazuhiko,Asakawa, Takeshi Korea Information Processing Society 2008 Journal of information processing systems Vol.4 No.4
VLSI chips have been tested using various automatic test equipment (ATE). Although each ATE has a similar structure, the language for ATE is proprietary and it is not easy to convert a test program for use among different ATE vendors. To address this difficulty we propose a tester structure expression language, a tester language with a novel format. The developed language is called the general tester language (GTL). Developing an interpreter for each tester, the GTL program can be directly applied to the ATE without conversion. It is also possible to select a cost-effective ATE from the test program, because the program expresses the required ATE resources, such as pin counts, measurement accuracy, and memory capacity. We describe the prototype environment for the GTL and the tester selection tool. The software size of the prototype is approximately 27,800 steps and 15 manmonths were required. Using the tester selection tool, the number of man-hours required in order to select an ATE could be reduced to 1/10. A GTL program was successfully executed on actual ATE.
Novel Pathogenetic Mechanism in a Clinical Isolate ofYersinia enterocolitica KU14
Matsuhisa Inoue,Kenichi Kaneko,Takeshi Sasahara,Yoshinori Sato 한국미생물학회 2006 The journal of microbiology Vol.44 No.1
Yersinia enterocolitica induces a broad range of gastrointestinal syndromes, including acute enteritis. We previously reported that the clinical isolate, Y. enterocolitica KU14, which lacks pYV, was still capable of causing clinical infection. The present study demonstrated that KU14 did not trigger the death of macrophages in vitro, unlike WA-314 (ATCC51871, which harbors the pYV virulence plasmid). However, the intracellular growth of KU14 in the macrophages was greater than that of WA-C (ATCC51872, a non-plasmid harboring the derivative pYV plasmid). Treatment with a cholesterol-binding drug (β-cyclodextrin) that affected lipid rafts resulted in a dramatic reduction in the intracellular growth of KU14. These data clearly indicate that the enhanced intracellular growth of KU14 is related to lipid raft-mediated infection.
Sueyoshi, Mitsuhiro,Furue, Toshihiko,Sato, Akihiro,Yokoyama, Kenichi,Yamadera, Yoshimi,Fujiwara, Kiyoshi,Matsuda, Katsuhiko 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.5
Aluminum brass tubing which is highly cost-effective and has a high heat transfer property has been widely used for seawater cooled condenser in Japan. However, the tubing suffers from erosion and corrosion on the inner surface in spite of ferric-ion injection and cathodic protection. Ammonia also attacks the outer surface after long years of service. Periodic replacement with new tubing has been performed. Titanium tubing which has high corrosion resistance, has been used in new condensers and for the air removal zone of the condenser. However, its service has been restricted due to higher cost and lower elastic modulus. As a countermeasure, we have developed a high performance ferritic stainless steel tubing called "Super Stainless: FS1O" which has excellent corrosion resistance and is highly cost-effective. First, the tubings were used experimentally in our Buzen thermal power station, Unit 2 condenser in 1993, and various investigations have been performed on the extracted tubing and tube sheet every year. Ammonia attack on the outer surface, corrosion and erosion on the inner surface, crevice corrosion between the tube and the tube-sheet. Hz absorption and degradation of properties was not observed. Based on these results, 1,006 pieces of FS1O were installed in Buzen thermal power station, Unit I condenser in 1996. The tubing has been used in seawater without any corrosion problems.
HISANORI SHINOHARA,PALANISAMY RAMESH,KENICHI SATO,YUJI OZEKI,MASAHITO YOSHIKAWA,NAOKI KISHI,TOSHIKI SUGAI 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2006 NANO Vol.1 No.3
Carbon nanotubes with 1–6 walls have been grown on cobalt-loaded mesoporous silica (i.e., MCM41) by using acetylene catalytic chemical vapor deposition. It is found that titanium grafting on the MCM41 pore walls prior to cobalt loading promotes the growth of nanotubes with 1–6 walls. As-grown nanotube material is found to be a mixture of single-wall carbon nanotubes (SWNTs), double-wall carbon nanotubes (DWNTs) and thin-multiwall carbon nanotubes (t-MWNTs) with 3–6 walls. Annealing of the as-grown nanotubes has reduced the amount of SWNTs in the nanotube mixture. Several structural deformations of the t-MWNTs are observed during transmission electron microscopy (TEM) analysis. Complete or partial collapse of the t-MWNTs is also found due to these structural deformations. Graphite-like domains developed at the collapsed regions stabilize these structural deformations.