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      • KCI등재

        Performance Analysis of MCDD in an OBP Satellite Communications System

        Sanggoo Kim,윤동원 한국통신학회 2010 Journal of communications and networks Vol.12 No.6

        Multi-carrier demultiplexer/demodulator (MCDD) in an on-board processing (OBP) satellite used for digital multimedia services has two typical architectures according to the channel demultiplexing procedure: Multistage multi-carrier demultiplexer (M-MCD) or poly-phase fast Fourier transform (PPF). During the channel demultiplexing, phase and quantization errors influence the performance of MCDD; those errors affect the bit error rate (BER) performance of M-MCD and PPF differently. In this paper,we derive the phase error variances that satisfy the condition that M-MCD and PPF have the same signal to noise ratio according to quantization bits, and then, with these results, analyze the BER performances of M-MCD and PPF. The results provided here may be a useful reference for the selection of M-MCD or PPF in designing the MCDD in an OBP satellite communications system.

      • Clostridium ganghwense sp. nov., isolated from tidal flat sediment.

        Kim, Seil,Jeong, Hyunyoung,Kim, Sanggoo,Chun, Jongsik Society for General Microbiology 2006 International journal of systematic and evolutiona Vol.56 No.4

        <P>A Gram-negative, strictly anaerobic, halophilic, motile, sporulating and rod-shaped bacterium, designated strain HY-42-06T, was isolated from tidal flat sediment from Ganghwa Island in South Korea. The isolate produced glycerol, ethanol and CO2 as fermentation end-products from glucose. Strain HY-42-06T grew optimally at 35 degrees C, pH 7.5 and 3 % (w/v) artificial sea salts. No growth was observed in the absence of sea salts. In phylogenetic analyses based on 16S rRNA gene sequence, strain HY-42-06T showed a distinct phyletic line within the members of cluster I of the order Clostridiales. The closest phylogenetic neighbour to strain HY-42-06T was Clostridium novyi ATCC 17861T (94.91 % 16S rRNA gene sequence similarity). Several phenotypic characters readily differentiate the tidal flat isolate from phylogenetically related clostridia. On the basis of polyphasic evidence, strain HY-42-06T should be classified as a representative of a novel species, for which the name Clostridium ganghwense sp. nov. is proposed. The type strain is HY-42-06T (=IMSNU 40127T = KCTC 5146T = JCM 13193T).</P>

      • Heterogeneous rRNAs are differentially expressed during the morphological development of Streptomyces coelicolor.

        Kim, Hyun-Lee,Shin, Eun-Kyoung,Kim, Hong-Man,Ryou, Sang-Mi,Kim, Sanggoo,Cha, Chang-Jun,Bae, Jeehyeon,Lee, Kangseok Published by Elsevier/North Holland on behalf of t 2007 FEMS microbiology letters Vol.275 No.1

        <P>It is generally assumed that all mature rRNA molecules assembled into ribosomes within a single cell are identical. However, sequence analysis of Streptomyces coelicolor genome revealed that it harbors six copies of divergent rRNA operons that may express and constitute three and five different kinds of small subunit (SSU) and large subunit (LSU) rRNA molecules, respectively, in a single cell. Phylogenetic analyses of the LSU rRNA genes and the internal transcribed spacer between SSU and LSU genes indicated that the LSU gene of rrnA and rrnE operons might be the result of interspecies recombination between rRNA genes in closely related streptomycetes. Profiling of rRNA species using primer extension analysis showed that heterogeneous rRNA transcripts are expressed and assembled into ribosomes in the cell. As the cells developed from germination to sporulation, the relative amount of LSU rRNA molecules derived from three rRNA operons (rrnA, D, and E) gradually decreased from approximately 85% to approximately 60%, whereas the distribution of LSU rRNA molecules from two other operons (rrnB and F) and rrnC operon gradually increased from approximately 10% to approximately 20% of the total LSU rRNA. These findings indicate that heterogeneous rRNA molecules are differentially expressed during the life cycle of this developmentally complex microorganism.</P>

      • KCI등재

        Rapid Targeted Sequencing Using Dried Blood Spot Samples for Patients With Suspected Actionable Genetic Diseases

        Kim Man Jin,Kim Soo Yeon,Lee Jin Sook,Kang Sanggoo,Park Lae-Jeong,Choi Wooyong,Jung Ju Yeol,Kim Taehyung,Park Sung Sup,Ko Jung Min,Seong Moon-Woo,Chae Jong Hee 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.3

        Background: New genome sequencing technologies with enhanced diagnostic efficiency have emerged. Rapid and timely diagnosis of treatable rare genetic diseases can alter their medical management and clinical course. However, multiple factors, including ethical issues, must be considered. We designed a targeted sequencing platform to avoid ethical issues and reduce the turnaround time. Methods: We designed an automated sequencing platform using dried blood spot samples and a NEOseq_ACTION panel comprising 254 genes associated with Mendelian diseases having curable or manageable treatment options. Retrospective validation was performed using data from 24 genetically and biochemically confirmed patients. Prospective validation was performed using data from 111 patients with suspected actionable genetic diseases. Results: In prospective clinical validation, 13.5% patients presented with medically actionable diseases, including short- or medium-chain acyl-CoA dehydrogenase deficiencies (N=6), hyperphenylalaninemia (N=2), mucopolysaccharidosis type IVA (N=1), alpha thalassemia (N=1), 3-methylcrotonyl-CoA carboxylase 2 deficiency (N=1), propionic acidemia (N=1), glycogen storage disease, type IX(a) (N=1), congenital myasthenic syndrome (N=1), and citrullinemia, type II (N=1). Using the automated analytic pipeline, the turnaround time from blood collection to result reporting was <4 days. Conclusions: This pilot study evaluated the possibility of rapid and timely diagnosis of treatable rare genetic diseases using a panel designed by a multidisciplinary team. The automated analytic pipeline maximized the clinical utility of rapid targeted sequencing for medically actionable genes, providing a strategy for appropriate and timely treatment of rare genetic diseases.

      • KCI등재

        달 탐사를 위한 한국형 심우주 지상국

        김상구(Sanggoo Kim),윤동원(Dongweon Yoon),현광민(Kwangmin Hyun) 한국항공우주학회 2010 韓國航空宇宙學會誌 Vol.38 No.5

        세계 각국은 이미 우주 개발을 위한 치열한 경쟁에 돌입하였으며, 우리나라도 2020년에 달 탐사선 발사 및 2025년에 달 착륙선 발사를 계획하고 있다. 우리나라 달 탐사 계획을 성공적으로 수행하기 위해서는 심우주 통신 기술 및 지상국 설치등과 같은 심우주 관련 기술 개발이 필요하다. 이를 위하여 심우주 관련 선진국들과의 협력을 통하여 축적된 경험 및 기술을 바탕으로 한국형 달 탐사 임무에 적합한 심우주 통신 방식을 개발하고 독자적인 지상국을 확보하여야 한다. 본 논문에서는 우리나라의 DSN을 성공적으로 정착시키기 위하여 국외 DSN과 심우주 통신 기술에 대해서 살펴보고, 이를 바탕으로 링크 마진을 비롯한 여러 가지 기술적 요구사항을 제시하며 우리나라의 달 탐사 계획을 위해 필요한 최적의 지상국 확보 전략을 제안한다. Many countries of the world have been launched the competition of space development and Korea also has a plan for the launch of Lunar orbiter in 2020 and Lunar lander in 2025 for Lunar explorations. For the success of the planned Lunar exploration, we need to enhance the required deep space communication technologies. To achieve our goals, we should develop space communications system and Korean DSN (deep space network) based on experiences and technologies through cooperation with the advanced countries in the field of deep space exploration. In this paper, we investigate overseas DSNs and deep space communication systems, and present the link margin and other technical requirements for successful DSN deployment. In addition, we propose a best strategy to secure domestic ground stations for the Korean Lunar exploration missions.

      • KCI등재

        LTE-Advanced 시스템에서 셀간 간섭 회피 및 전력 제어 결합 성능 분석

        김상구(Sanggoo Kim),임성호(Sungho Lim),윤동원(Dongweon Yoon) 大韓電子工學會 2010 電子工學會論文誌-TC (Telecommunications) Vol.47 No.12

        LTE-Advanced 시스템은 각 섹터에서 모든 주파수 자원을 사용하기 때문에 셀 경계부에 위치한 사용자들은 인접 셀의 주파수 간섭을 받게 되어 사용자 전송률이 크게 저하 된다. 본 논문은 셀 경계부에서 셀간 간섭 회피를 위한 주파수 할당 방법과 전력 제어를 결합하는 알고리즘을 제안하고 사용자 전송률을 분석한다. 제안하는 알고리즘은 간섭 신호의 영향을 회피하기 위해 섹터의 중심부와 섹터의 좌측 경계부, 우측 경계부 3개 부분으로 나누어 각각 다른 주파수를 할당하고, 원하지 않는 간섭신호를 작게 하기 위해 송신 전력을 조절함으로써 셀 경계부의 사용자 전송률을 향상시킨다. 시스템 레벨 컴퓨터 모의실험을 통하여 셀간 간섭 회피 기법을 사용하지 않은 경우와 사용한 경우, 그리고 셀간 간섭 회피 기법과 전력 제어를 결합했을 경우 셀 전체, 셀 중심부, 셀 경계부에 위치한 사용자들의 평균 전송률 및 하위 5% 사용자의 평균 전송률을 비교 분석한다. In LTE-Advanced systems, every sector uses the entire range of the frequency resource, and when the UEs are located at a cell edge, user throughputs degrade due to the interferences from the adjacent cells. In this paper, we propose a combined scheme for inter-cell interference avoidance and power control. In the proposed algorithm, the sectors consist of the right edge, the left edge and the center for resource allocation and we control the transmission power to improve the user throughputs at the edge of each cell. Using a system level simulation, we analyze low 5th percentile and average user throughputs of the UEs who are located the cell, center and edge when the inter-cell interference avoidance and the power control are combined.

      • 밸브안착속도가 LPG엔진 밸브계 거동에 미치는 영향에 관한 연구

        김승철(SeungChul Kim),김청균(ChungKyun Kim),이경식(KyoungSik Lee),이한열(HanYeol Lee),김상구(SangGoo Kim) 한국자동차공학회 2010 한국자동차공학회 학술대회 및 전시회 Vol.2010 No.11

        Due to better emission for CO2 and fine dust (PM10) than diesel and gasoline vehicles, LPG engine that is called low pollutant one is recently adopted for passenger car as well as commercial one and its demand gets growing year by year. The main part that should be replaced in the existing gasoline engine because of the lack of durability is intake and exhaust valves and their seats. This is because LPG has lower lubrication capability than gasoline and also supplying combustion chamber with gas state makes the durability of valve system weaker. Furthermore higher thermal load on exhaust valve system and the lack of combustion products are very tough conditions for adhesive wear. In this point, the effect on adhesive wear through the measurement of behavior change of valves according to seating has been evaluated and the solution to decrease it has been searched. So this study searched the behavior change of valve seating velocity through the redesign of cam profile ramp and confirmed the change of valve seating velocity contributed to decreasing engine wear and its noise.

      • 전자상거래 환경에서의 분류체계 자동 통합 기법

        김재범(Jaebeom Kim),김동규(Dongkyu Kim),이상구(Sanggoo Lee) 한국정보과학회 2000 한국정보과학회 학술발표논문집 Vol.27 No.2Ⅰ

        인터넷은 단순한 정보 교환의 수단이 아니라 기업들의 이윤 창출을 위한 새로운 공간이 되고 있으며 수많은 쇼핑몰들이 이를 설명해 주고 있다. 하지만 분류체계 측면에서 각 쇼핑몰들이 제공하고 있는 분류체계에는 크게 다음 두 가지의 문제점이 있다. 첫째로 각 쇼핑몰마다 서로 다른 자기만의 상품 분류체계를 가지고 있다는 점이다. 이로 인해 쇼핑몰을 이용하고자 하는 사용자는 각 쇼핑몰을 방문할 때 마다 혼란스러울 수 밖에 없다. 두 번째는 각 쇼핑몰이 제공하고 있는 분류체계는 정적인 형태만을 띄고 있다는 점이다. 따라서 이러한 문제들을 해결하기 위하여 본 논문에서는 규칙이라는 추가 정보를 가지도록 모델링된 쇼핑몰의 분류체계들에 대하여 자동적인 통합의 기법을 제시한다. 제시된 기법에 의하여 쇼핑몰 사용자들에게 모든 쇼핑몰의 통합된 뷰의 제공, 사용자별 분류체계의 생성, 메타 쇼핑몰 간의 통일된 인터페이스 제공 등을 할 수 있다.

      • KCI우수등재

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