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류지성,정규혁,최필선,이길철,최덕일,최성수,류홍일,박광식 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1
Cadmium, a major aquatic pollutant in many parts of the world, is toxic and readily accumulated in aquatic organisms. It mainly exists in water as complexes with organic ligands such as dissolved organic carbon and this complexation is known to have effects on the aquatic toxicities. In this study, acute toxicity, histology, and bioaccumulation were studied to evaluate effects of humic acid on cadmium toxicity and bioavailability to fish using Oryzias latipes and Cyprinus carpio. 96h-LC50 of cadmium was 6.38 ㎎/L using Oryzias latipes. However, the mortality showed the dose-dependent decrease when humic acid was added to the test solution. When fish were exposed to 5㎎/L of cadmium, histological changes in the exposed organs(caudal fins, gills, kidney, liver, and gut) of Cyprinus carpio were decreased by humic acid, especially in kidney and liver. Bioaccumulation of cadmium also decreased by treatment of humic acid. It seems that the formation of complexes between cadmium and humic acid may decrease bioavailability of cadmium to fish, and thus reduce the toxic effects of cadmium.
Utility accrual real-time scheduling for (m, k)-firm deadline-constrained streams on multiprocessors
Rhu, J.-H,Sun, J.-H,Kim, K,Cho, H,Park, J K IET 2011 Electronics letters Vol.47 No.5
<P>Considering video conferencing applications, presented is the first utility accrual (or UA) real-time scheduling algorithm for multiple (<I>m</I>, <I>k</I>)-firm deadline-constrained streams running on multiprocessors, called the global multiprocessor utility accrual scheduling algorithm for (<I>m</I>, <I>k</I>)-firm deadline-constraint multimedia streams (or gMUA-MK). Analytical and experimental studies show that gMUA-MK achieves timeliness performance and relatively high quality of multimedia services compared to existing schemes including gMUA.</P>
류지성,정규혁,최필선,이길철,최덕일,최성수,류홍일,박광식 한국환경독성학회 1998 환경독성보건학회지 Vol.13 No.1
Cadmium, a major aquatic pollutant in many parts of the world, is toxic and readily accumulated in aquatic organisms. It mainly exists in water as complexes with organic ligands such as dissolved organic carbon and this complexation is known to have effects on the aquatic toxicities. In this study, acute toxicity, histology, and bioaccumulation were studied to evaluate effects of humic acid on cadmium toxicity and bioavailability to fish using Oryzias latipcs and Cypriruts carpio. 96h~LC50 of cadmium was 6.38 mg/L using Oryzias latipes. However, the mortality showed the dose-dependent decrease when humic acid was added to the test solution. When fish were exposed to 5 mg/L of cadmium, histological changes in the exposed organs (caudal fins, gills, kidney, liver, and gut) of Cyprinifs carpio were decreased by humic acid, especially in kidney and liver. Bioaccumulation of cadmium also decreased by treatment of humic acid. It seems that the formation of complexes between cadmium and humic acid may decrease bioavailability of cadmium to fish, and thus reduce the toxic effects of cadmium.
An Expand of Oligopoly Theory and Commercial Policy to International Trade
Rhu, Duk-Wi,Min, Kyung-Se 大田工業大學 1992 한밭대학교 논문집 Vol.9 No.2
Recently, with growth of industrial organization theories, there seems to be necessary for an intergration of industrial organization theories and international trade theories. This paper applied Cournot and Bertrand's duopoly model to international trade theory and analyzed producer's revenue.
Jinsoo Rhu,임소영,Danbee Kang,Juhee Cho,Heesuk Lee,Gyu-Seong Choi,Jong Man Kim,Jae-Won Joh 한국간담췌외과학회 2022 Annals of hepato-biliary-pancreatic surgery Vol.26 No.3
Three-dimensional (3D) modeling of the liver can be especially useful for both the surgeon and patient to understand the actual location of the tumor and planning the resection plane. Virtual reality (VR) can enhance the understanding of 3D structures and create an environment where the user can focus on contents provided. In the present study, a VR platform was developed using Unreal Engine 4 software (Epic Games, Potomac, MD, USA). Patient’s liver based on magnetic resonance image was imported as a 3D model that could distinguish liver parenchyma, vascular structure, and cancer. Preoperative education videos for patients were developed. They could be viewed inside the VR platform. To evaluate the usefulness of VR education program for patients undergoing liver resection for hepatocellular carcinoma, a randomized clinical trial evaluating the knowledge and anxiety of the patient was designed. The case presented in this report was the first experience of performing the VR education program and examining the knowledge and anxiety using questionnaires. When the knowledge score increased, the anxiety score also increased after the education program. Based on findings of this pilot case study, the timing and place where the questionnaire will be answered can be modified for formal initiation of the randomized controlled study to examine the usefulness of VR in patient education.
( Jinsoo Rhu ),( Jong Man Kim ),( Gyu-seongchoi ),( Jae-won Joh ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: This study was designed to analyze the impact of venous outflow congestion in the liver graft on hepatocellular carcinoma recurrence with liver transplantation Methods: Hepatocellular carcinoma patients who underwent living donor liver transplantation in Samsung Medical Center between 2007 and 2018 were reviewed. Based on 2-week post-transplantation computed tomography, volume of the congested parenchyma was calculated. Patients were divided into five groups based on the congestion volume. Recurrence-free survival and overall survival was analyzed using multivariable Cox proportional hazard model including the degree of venous congestion. Results: A total of 582 patients were included. There were 350 patients (60.1%) with no congestion, while congestion volume less than 100 ㎤, between 100 to 200 ㎤, between 200 to 300 ㎤, and ≥300 ㎤ were present in 58 (10.0%), 109 (18.7%), 40 (6.9%) and 25 (4.3%), respectively. Congestion volume (P=0.008) was a significant risk factor recurrence-free survival. Congestion volume of ≥300 ㎤ (HR=3.349, CI=1.703-6.587, P<0.001) showed significantly poorer recurrence-free survival compared to patients with no congestion. Conclusions: Venous outflow congestion in the liver after living donor liver transplantation was related to poor recurrence-free survival of hepatocellular carcinoma.
Jinsoo Rhu,Jong Man Kim,Gyu Seong Choi,Choon Hyuck David Kwon,Jae-Won Joh,Olivier Soubrane 대한외과학회 2018 Annals of Surgical Treatment and Research(ASRT) Vol.95 No.5
Purpose: This study analyzes the impact of laparoscopic liver resection on intra-abdominal adhesion. Methods: Patients who underwent salvage liver transplantation after liver resection for hepatocellular carcinoma from January 2012 to October 2017 at our institution were included. Information about the severity of intra-abdominal adhesions was collected from a prospectively maintained database. Intra-abdominal adhesions were graded after the agreement of 2 surgeons who participated in the salvage liver transplantation based on predetermined criteria. Adhesion severity and demographic, operative, and postoperative data were compared between the laparoscopic group and the open group. Multivariate logistic regression was performed to consider potential factors related to severe adhesion during salvage transplantation. Results: Sixty-two patients who underwent salvage liver transplantation after liver resection were included in this study. Among them, 52 patients underwent open surgery, and 10 patients underwent laparoscopy. Adhesion was significantly more severe in the open group than in the laparoscopy group (P = 0.029). A multivariate logistic regression model including potential factors related to severe adhesion showed that laparoscopy (odds ratio, 0.168; 95% confidence interval, 0.029–0.970; P = 0.048) was the only significant factor. Conclusion: Laparoscopic liver resection for hepatocellular carcinoma can minimize intra-abdominal adhesion during salvage liver transplantation.