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      • KCI등재후보

        Evaluation of the analgesic and anti-inflammatory properties of methanolextract of Artanema sesamoides Benth roots in animal models

        Malaya Gupta,UK Mazumder,V Thamil Selvan,L Manikandan,Senthilkumar GP,R Suresh,P Gomathi,B Ashok Kumar 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.2

        The methanol extract of the root of Artanema sesamoides Family Scrophuilariaceae (MEAS) was investigated for possible analgesic and anti-inflammatory effects in animals. Three models were used to study the extract effects on nociception, which were acetic acid-induced writhing response, hot-plate method and the tail flick test in mice. The antiinflammatory effects were evaluated using carrageenan, dextran, histamine and serotonin induced rat paw oedema (acute) and cotton pellet induced granuloma (chronic) models in rats. Results of the study revealed that the extract exhibited significant (P < 0.001) analgesic effect at a dose of 50, 100 and 200 mg/kg b.w p.o in mice in all the models. In acute model, the MEAS also exhibited significant (P < 0.001) antiinflammatory effect in all the above mentioned doses. In chronic model (cotton pellet induced granuloma) the MEAS 200 mg/kg and indomethacin 10 mg/kg showed that inhibition of granuloma formation 25.0% and 47.7% respectively (P < 0.001). The MEAS and indomethacin were effectively preventing the transudation of the fluid. Thus, the present study revealed that the methanol extract of the root of Artanema sesamoides exhibited significant analgesic and antiinflammatory activity. The methanol extract of the root of Artanema sesamoides Family Scrophuilariaceae (MEAS) was investigated for possible analgesic and anti-inflammatory effects in animals. Three models were used to study the extract effects on nociception, which were acetic acid-induced writhing response, hot-plate method and the tail flick test in mice. The antiinflammatory effects were evaluated using carrageenan, dextran, histamine and serotonin induced rat paw oedema (acute) and cotton pellet induced granuloma (chronic) models in rats. Results of the study revealed that the extract exhibited significant (P < 0.001) analgesic effect at a dose of 50, 100 and 200 mg/kg b.w p.o in mice in all the models. In acute model, the MEAS also exhibited significant (P < 0.001) antiinflammatory effect in all the above mentioned doses. In chronic model (cotton pellet induced granuloma) the MEAS 200 mg/kg and indomethacin 10 mg/kg showed that inhibition of granuloma formation 25.0% and 47.7% respectively (P < 0.001). The MEAS and indomethacin were effectively preventing the transudation of the fluid. Thus, the present study revealed that the methanol extract of the root of Artanema sesamoides exhibited significant analgesic and antiinflammatory activity.

      • Physical Factors in Relation to Conidial Germination in Alternaria porri, the Incitant of Purple Blotch of Onion

        R.B.L. 굽타,V.N. 파닥,O.P. 베르마,Gupta, R.B.L.,Pathak, V.N.,Verma, O.P. Korean Society of Applied Entomology 1985 한국식물보호학회지 Vol.24 No.3

        Influence of temperature, relative humidity, spore washing and spore drying on conidial germination of Alternaria porri(Ell.) Cif. was studied. Maximum conidial germination occurred at 100% relative humidity prevailing for 6 hours or more at $25^{\circ}C$. Conidial germination decreased with increase in number of spore washings. Drying of conidia for more than half an hour caused significant decrease in germination. In all the experiments, conidial germinatio increased with increase in incubation period.

      • KCI등재

        양파검은무늬병균의 포자발아에 미치는 물리적 요인

        R.B.L. GUPTA,V.N. PATHAK,O.P. VERMA 한국응용곤충학회 1985 한국응용곤충학회지 Vol.24 No.3

        Influence of temperature, relative humidity, spore washing and spore drying on conidial germination of Alternaria porri(Ell.) Cif. was studied. Maximum conidial germination occurred at 100% relative humidity prevailing for 6 hours or more at . Conidial germination decreased with increase in number of spore washings. Drying of conidia for more than half an hour caused significant decrease in germination. In all the experiments, conidial germinatio increased with increase in incubation period.

      • Multi-Secondary Transformer: A Modeling Technique for Simulation - II

        Patel, A.,Singh, N.P.,Gupta, L.N.,Raval, B.,Oza, K.,Thakar, A.,Parmar, D.,Dhola, H.,Dave, R.,Gupta, V.,Gajjar, S.,Patel, P.J.,Baruah, U.K. Journal of International Conference on Electrical 2014 Journal of international Conference on Electrical Vol.3 No.1

        Power Transformers with more than one secondary winding are not uncommon in industrial applications. But new classes of applications where very large number of independent secondaries are used are becoming popular in controlled converters for medium and high voltage applications. Cascade H-bridge medium voltage drives and Pulse Step Modulation (PSM) based high voltage power supplies are such applications. Regulated high voltage power supplies (Fig. 1) with 35-100 kV, 5-10 MW output range with very fast dynamics (${\mu}S$ order) uses such transformers. Such power supplies are widely used in fusion research. Here series connection of isolated voltage sources with conventional switching semiconductor devices is achieved by large number of separate transformers or by single unit of multi-secondary transformer. Naturally, a transformer having numbers of secondary windings (~40) on single core is the preferred solution due to space and cost considerations. For design and simulation analysis of such a power supply, the model of a multi-secondary transformer poses special problem to any circuit analysis software as many simulation softwares provide transformer models with limited number (3-6) of secondary windings. Multi-Secondary transformer models with 3 different schemes are available. A comparison of test results from a practical Multi-secondary transformer with a simulation model using magnetic component is found to describe the behavior closer to observed test results. Earlier models assumed magnetising inductance in a linear loss less core model although in actual it is saturable core made-up of CRGO steel laminations. This article discusses a more detailed representation of flux coupled magnetic model with saturable core properties to simulate actual transformers very close to its observed parameters in test and actual usage.

      • KCI등재

        X-ray/gamma radiation shielding properties of Aluminium-Barium Zinc Oxide nanoparticles synthesized via low temperature solution combustion method

        Sathish K.V.,Sridhar K.N.,Seenappa L.,Manjunatha H.C.,Vidya Y.S.,Chinnappa Reddy B.,Manjunatha S.,Santhosh A.N.,Munirathnam R.,Raj Alfred Cecil,Damodara Gupta P.S.,Sankarshan B.M. 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.5

        For the first time Aluminium-BariumeZinc oxide nanocomposite (ZABONC) was synthesized by solution combustion method where calcination was carried out at low temperatures (6000 C) to study the electromagnetic (EM) (X/g) radiation shielding properties. Further for characterization purpose standard techniques like PXRD, SEM, UV-VISIBLE, FTIR were used to find phase purity, functional groups, surface morphology, and to do structural analysis and energy band gap determination. The PXRD pattern shows (hkl) planes corresponding to spinel cubic phase of ZnAl2O4, cubic BaðNO3Þ2, a and g phase of Al2O3 which clearly confirms the formation of complex nano composite. From SEM histogram mean size of nano particles was calculated and is in the order of 17 nm. Wood and Tauc’s relation direct energy band gap calculation gives energy gap of 2.9 eV. In addition, EM (X/g) shielding properties were measured and compared with the theoretical ones using standard procedures (NaI (Tl) detector and multi channel analyzer MCA). For energy above 356 keV the measured shielding parameters agree well with the theory, while below this value slight deviation is observed, due to the influence of atomic/crystallite size of the ZABONC. Hence synthesized ZABONC can be used as a shielding material in EM (X/g) radiation shielding

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