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Pandey Sudip,Pant Poonam 한국산림과학회 2023 Forest Science And Technology Vol.19 No.1
Tree bark contains anti-microbial, antioxidant, and anticancer compounds and are therefore widely used by pharmaceutical, cosmetics, and food industries as raw materials. Bark provides raw materials for adhesives, insulating materials, and even water purification. The article reviews the utilization of tree bark as a source of green chemicals and adhesives and the possibilities of their application in Nepal. The study also shows the direct utilization of bark as an insulating material and the extraction of chemicals as therapeutic. The extraction of chemicals from bark differs from species to species due to variations in chemical compositions. The study shows that despite the versatility of tree bark, Nepal hasn’t been using its benefits and utilized it just as waste. Finally, this paper discusses the perspective and challenges in the production of chemicals and materials from the bark.
Ritika Rajpoot,Anjana Rani,Rajneesh Kumar Srivastava,Poonam Pandey,R. S. Dubey 한국작물학회 2018 Journal of crop science and biotechnology Vol.21 No.4
Mentha arvensis L. (Ma) leaf extract, a wide source of natural antioxidants is widely used to protect animal cells against oxidative stress. In the current study, we have studied the ameliorative effects of Ma leaf extract on Mn induced oxidative stress in rice (Oryza sativa L.) seedlings. Hydroponically grown rice seedlings treated with 1.5 mM MnCl2 showed a decline in vigour and contents of photosynthetic pigments, increased production of reactive oxygen species (O2˙‾, H2O2, and .OH), lipid peroxidation, protein thiol and carbonyl contents along with increased activity of antioxidative enzymes- superoxide dismutase (SOD), guaiacol peroxidase (GPX) and ascorbate peroxidase (APX). The activity of catalase (CAT), however, declined in the seedlings after prolonged Mn treatment of 8 days. Interestingly exogenous application of Ma leaf extract (638.4 mg ml-1) effectively restored the Mn-induced decline in seedling vigour, photosynthetic pigments, increased levels of H2O2, lipid peroxides and altered activities of antioxidative enzymes. The results indicate that exogenous application of Ma leaf extract significantly lowers the toxic effects of Mn in rice seedlings by modulating Mn translocation and reducing oxidative stress.
Current Status of Stem Cell Treatment for Type I Diabetes Mellitus
Anupama Kakkar,Ashima Sorout,Mahak Tiwari,Pallavi Shrivastava,Poonam Meena,Sumit Kumar Saraswat,Supriya Srivastava,Rajan Datt,Siddharth Pandey 한국조직공학과 재생의학회 2018 조직공학과 재생의학 Vol.15 No.6
BACKGROUND: Diabetes mellitus is a major health concern in current scenario which has been found to affect people of almost all ages. The disease has huge impact on global health; therefore, alternate methods apart from insulin injection are being explored to cure diabetes. Therefore, this review mainly focuses on the current status and therapeutic potential of stem cells mainly mesenchymal stem cells (MSCs) for Type 1 diabetes mellitus in preclinical animal models as well as humans. METHODS: Current treatment for Type 1 diabetes mellitus mainly includes use of insulin which has its own limitations and also the underlying mechanism of diseases is still not explored. Therefore, alternate methods to cure diabetes are being explored. Stem cells are being investigated as an alternative therapy for treatment of various diseases including diabetes. Few preclinical studies have also been conducted using undifferentiated MSCs as well as in vitro MSCs differentiated into b islet cells. RESULTS: These stem cell transplant studies have highlighted the benefits of MSCs, which have shown promising results. Few human trials using stem cells have also affirmed the potential of these cells in alleviating the symptoms. CONCLUSION: Stem cell transplantation may prove to be a safe and effective treatment for patients with Type 1 diabetes mellitus.