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        Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT

        Gul Ege Aktas,Nuray Can,Selin Soyluoglu Demir,Ali Sarıkaya 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.1

        A 69-year-old male smoker was referred to 18Ff luorodeoxyglucose (FDG) pos i t r on emi s sion tomography-computed tomography (PET/CT) with the indication of a suspicious solitary pulmonary nodule. FDG PET/CT determined a 2.5 × 2-cm soft-tissue lesion (SUVmax, 16.2) with spiculated margins in the hilum of the right lung. A 1-cm diameter lymphadenopathy on the right hilum with an SUVmax of 3.2 was also determined. Transbronchial biopsy of the right hilar lymphadenopathy did not reveal any malignant features in histopathologic examination, and it was determined to be reactive. The patient underwent a right upper lobe segmentectomy, and the histopathologic evaluation revealed that the tumor was a primary lymphoepithelioma-like carcinoma (LELC) of the lung with negative Epstein-Barr virus (EBV) on in situ hybridization studies. In this case report, we mainly focus on the FDG avidity of this very rare kind of tumor comparatively with previous reports and possible explanations of discordancy in FDG avidity in relation to histopathologic characteristics.

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        Microcalcified Hepatic Metastases Incidentally Detected on F-18 NaF PET/CT in a Patient with Prostate Cancer

        Gul Ege Aktas,Ali Sarıkaya,Nuray Can,Selin Soyluoglu Demir 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.4

        F-18 NaF PET/CT evaluation has gained importance in recent years. Achievements from F-18 NaF PET/CT are: higher sensitivity of positron imaging, higher target background ratio with higher tracer accumulation in bone hydroxyapatite and higher specificity through CT correlation. These properties have also given directions to new research fields based on imaging microcalcifications, very recently. A limited number of cases have reported the F-18 NaF uptake in macrocalcified soft tissue metastases. Although the presence of microcalcification was not proved; accumulation of F-18 NaF in the metastatic brain lesion with no visible calcification on the CT, in a patient with ductal breast carcinoma has also been reported. Herein we present a patient with microcalcified hepatic metastasis of prostate cancer incidentally detected on F-18 NaF PET/CT which was confirmed with histochemical staining.

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        Evaluation of Temperament and Character Features as Risk Factors for Depressive Symptoms in Patients with Restless Legs Syndrome

        Vildan Altunayoglu Cakmak,Sibel Gazioglu,Nuray Can Usta,Ahmet Ayar,Murat Topbas,Cavit Boz,Evrim Ozkorumak 대한신경과학회 2014 Journal of Clinical Neurology Vol.10 No.4

        Background and Purpose Restless legs syndrome (RLS) is a common sleep-related movement disorder that is frequently associated with psychological disturbances. Personality traitsare of considerable importance with respect to coping with chronic illness and disease vulnerability. This study assessed the temperament and character traits of RLS patients using an approach that involves the psychobiological model of personality. Methods The personality features of 65 newly diagnosed and untreated RLS patients with noneurological or psychiatric diseases and 109 healthy controls were determined using the Temperament and Character Inventory and compared using covariance analyses. The InternationalRLS Study Group Severity Scale was used to assess the severity of the RLS symptoms, and theBeck Depression Inventory was used to assess the presence and severity of depressive symptoms. Results RLS patients scored significantly higher than healthy controls on the temperamentdimension of harm avoidance (HA, p=0.02) and significantly lower on self-directedness (SD,p=0.001). No significant difference was observed in terms of the temperament dimension ofnovelty seeking (p=0.435). HA scores were significantly correlated with the BDI score but notwith the RLS severity or duration. Conclusions High HA and low SD scores are the main characterizing personality features ofRLS patients. These personality dimensions may be among the factors predisposing patients todevelopment of the depressive symptoms that are frequently associated with RLS.

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