Morphine Spinal Block Anesthesia in Patients Who Undergo an Open Hemorrhoidectomy: A Prospective Analysis of Pain Control and Postoperative Complications

Hélio Moreira Jr,José PT Moreira,Raniere R Isaac,Onofre Alves-Neto,Thiago AC Moreira,Tiago HM Vieira,Andressa MS Brasil 대한대장항문학회 2014 Annals of Coloproctolgy Vol.30 No.3

Purpose: This study evaluated the use of adding morphine to bupivacaine in spinal anesthesia for pain control in patients who underwent an open hemorrhoidectomy. Methods: Forty patients were prospectively selected for an open hemorrhoidectomy at the same institution and were randomized into two groups of 20 patients each: group 1 had a spinal with 7 mg of heavy bupivacaine associated with 80 μg of morphine (0.2 mg/mL). Group 2 had a spinal with 7 mg of heavy bupivacaine associated with distilled water, achieving the same volume of spinal infusion as that of group 1. Both groups were prescribed the same pain control medicine during the postoperative period. Pain scores were evaluated at the anesthetic recovery room and at 3, 6, 12, and 24 hours after surgery. Postoperative complications, including pruritus, nausea, headaches, and urinary retention, were also recorded. Results: There were no anthropometric statistical differences between the two groups. Pain in the anesthetic recovery room and 3 hours after surgery was similar for both groups. However, pain was better controlled in group 1 at 6 and 12 hours after surgery. Although pain was better controlled for group 1 after 24 hours of surgery, the difference between the groups didn’t achieved statistical significance. Complications were more common in group 1. Six patients (6/20) presented coetaneous pruritus and 3 with (3/20) urinary retention. Conclusion: A hemorrhoidectomy under a spinal with morphine provides better pain control between 6 and 12 hours after surgery. However, postoperative complications, including cutaneous pruritus (30%) and urinary retention (15%), should be considered as a negative side of this procedure.

Cryopreservation of mesenchymal stem cells derived from dental pulp: a systematic review

Paes Sabrina Moreira,Pupo Yasmine Mendes,Cavenago Bruno Cavalini,Fonseca-Silva Thiago,Santos Carolina Carvalho de Oliveira 대한치과보존학회 2021 Restorative Dentistry & Endodontics Vol.46 No.2

Objectives: The aim of the present systematic review was to investigate the cryopreservation process of dental pulp mesenchymal stromal cells and whether cryopreservation is effective in promoting cell viability and recovery. Materials and Methods: This systematic review was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and the research question was determined using the population, exposure, comparison, and outcomes strategy. Electronic searches were conducted in the PubMed, Cochrane Library, Science Direct, LILACS, and SciELO databases and in the gray literature (dissertations and thesis databases and Google Scholar) for relevant articles published up to March 2019. Clinical trial studies performed with dental pulp of human permanent or primary teeth, containing concrete information regarding the cryopreservation stages, and with cryopreservation performed for a period of at least 1 week were included in this study. Results: The search strategy resulted in the retrieval of 185 publications. After the application of the eligibility criteria, 21 articles were selected for a qualitative analysis. Conclusions: The cryopreservation process must be carried out in 6 stages: tooth disinfection, pulp extraction, cell isolation, cell proliferation, cryopreservation, and thawing. In addition, it can be inferred that the use of dimethyl sulfoxide, programmable freezing, and storage in liquid nitrogen are associated with a high rate of cell viability after thawing and a high rate of cell proliferation in both primary and permanent teeth.

Pacing Strategy of Single Scullers during Rowing World Championships

Alexandre Nunes Martins,Thiago Oliveira Borges,Reury Frank Bacurau,Alexandre Moreira,Marcelo Saldanha Aoki 국민체육진흥공단 한국스포츠정책과학원 2022 International Journal of Applied Sports Sciences Vol.34 No.2

This study aimed to describe and compare the pacing strategy and performance of world level under 19 (U19), under 23(U23) and senior single scullers during world championship races. Data are from 8 years of Rowing World Championships A and B finals of single scull races for U19, U23 and senior age scullers. Pacing was determined for velocity, stroke rate and, distance per stroke (SD). Scullers presented a fast start strategy for all races investigated. There was no significant difference in pacing between age groups. Velocity peaked at the 100m (U19) and 150m (U23 and senior) mark. The scullers in the older age groups showed superior performance scores of the studied variables. U19, Under 23 and senior single scullers present similar pacing regardless of their age group. Performance of single sculler improve from U19, to U23 to senior for both lightweight and heavyweight classes. The results of this study may serve as a reference for athletes, coaches, and sports scientists to be implemented in training.

Energetic, Exergetic, Environmental, and Economic Assessment of a Cascade Refrigeration System Operating with Four Different Ecological Refrigerant Pairs

de Paula Cleison Henrique,Duarte Willian Moreira,Rocha Thiago Torres Martins,de Oliveira Raphael Nunes,Maia Antônio Augusto Torres 대한설비공학회 2021 International Journal of Air-Conditioning and Refr Vol.29 No.3

In this work, a cascade refrigeration system operating with four different ecological refrigerant pairs was modeled. This system uses R744 (Carbon dioxide) in the low-temperature cycle and operates with R290 (propane), R1234yf (2,3,3,3-tetrafluoropropene), R152a (1,1-difluorethane), and R717 (ammonia) in the high-temperature cycle. Energetic, exergetic, environmental, and economic performance of the cascade system was investigated to determine the most appropriate ecological refrigerant couple. The parameters used in each mentioned performance were COP (Coefficient of Performance), [Formula: see text] (Exergy Efficiency), TEWI (Total Equivalent Warming Impact), ECOP (Ecological coefficient of performance), and [Formula: see text] (Total plant cost rate), respectively. The results showed that the cascade refrigeration system operating with R744/R717 provided the best performance for the thermodynamic conditions analyzed, presenting a COP of 2.10, [Formula: see text] of 56.9%, [Formula: see text] of 24 334 USD/year, ECOP of 4.86, and TEWI of 25.67 tons of CO 2 . Finally, evaluating the total plant cost rate of this cascade system, it was noted that the capital and maintenance cost rate [Formula: see text] corresponds to 89.1% of the [Formula: see text] value, the operational cost rate [Formula: see text] corresponds to 10.27% of the [Formula: see text] value and the environmental cost rate [Formula: see text] corresponds to 0.63% of [Formula: see text].

Provision of a protein-rich supplement for grazing suckling female beef calves to improve productive performance and metabolic response

Moreno Deilen S,Ortega Román M,Marquez David C,Moreira Thiago R,Santos Edson J dos,Almeida Daniel M de,Paulino Mário Fonseca,Rennó Luciana Navajas,Detmann Edenio 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.8

Objective: This study was conducted to evaluate the effects of the provision of a proteinrich supplement on productive performance, and metabolic profile on grazing suckling female beef calves in tropical conditions during 150 d of experimentation. Methods: Fifty-six Nellore suckling female calves, and their respective dams were distributed in a completely randomised design and made to undergo two treatments as follows: UNS (without supplementation), and SUP (supplementation with 5 g/kg body weight [BW] of a protein supplement). Throughout the experiment, animal performance and metabolic profile were evaluated. Also, ureagenesis and gluconeogenesis were assessed for gene expression. Results: SUP female calves showed a higher voluntary intake (p≤0.03) of the diet components evaluated, digestibility of organic matter (p≤0.02) and microbial nitrogen production (MICN; p≤0.02) compared to UNS female calves. In its turn, serum urea nitrogen (p≤0.01) and insulin-like growth factor-1 (p≤0.03) levels and ureagenesis (p≤0.04) increased in SUP female calves compared to UNS female calves. Blood glucose and triglyceride levels were not affected by supplementation. The average daily gain (ADG) from SUP female calves was higher (p≤0.02) compared with UNS female calves. However, supplementation did not affect the body measures of the animals. Conclusion: In summary, provision of a protein-rich supplement improves the intake and nutrients digestibility, ADG and final BW and increases metabolic indicators of the protein status in grazing suckling female beef calves in tropical conditions. Objective: This study was conducted to evaluate the effects of the provision of a protein-rich supplement on productive performance, and metabolic profile on grazing suckling female beef calves in tropical conditions during 150 d of experimentation.Methods: Fifty-six Nellore suckling female calves, and their respective dams were distributed in a completely randomised design and made to undergo two treatments as follows: UNS (without supplementation), and SUP (supplementation with 5 g/kg body weight [BW] of a protein supplement). Throughout the experiment, animal performance and metabolic profile were evaluated. Also, ureagenesis and gluconeogenesis were assessed for gene expression.Results: SUP female calves showed a higher voluntary intake (p≤0.03) of the diet components evaluated, digestibility of organic matter (p≤0.02) and microbial nitrogen production (MICN; p≤0.02) compared to UNS female calves. In its turn, serum urea nitrogen (p≤0.01) and insulin-like growth factor-1 (p≤0.03) levels and ureagenesis (p≤0.04) increased in SUP female calves compared to UNS female calves. Blood glucose and triglyceride levels were not affected by supplementation. The average daily gain (ADG) from SUP female calves was higher (p≤0.02) compared with UNS female calves. However, supplementation did not affect the body measures of the animals.Conclusion: In summary, provision of a protein-rich supplement improves the intake and nutrients digestibility, ADG and final BW and increases metabolic indicators of the protein status in grazing suckling female beef calves in tropical conditions.