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RISS 인기검색어
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- 저자 : Mirzajani, Mohammad Reza (검색결과 5 건)
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Metal Concentrations in the Coastal Fauna of the Caspian Sea
Mirzajani Alireza,Hamidian Amir Hossein,Hassan Jalal 한국해양과학기술원 2021 Ocean science journal Vol.56 No.3
Metal concentrations were measured in predominant coastal fauna of the Caspian Sea including six macro-invertebrates (Mnemiposis leidyi, Balanus improvisus, Pontogammarus maeoticus, Palaemon adspersus, Cerastoderma glucaum and Adacna vitrea) and three species of small fish (Atherina caspia, Neogobius caspius and N. pallasi) to determine potential bio-indicators (for the first time to our knowledge). It is to be noted that metal concentrations have also never been reported in M. leidyi and A. vitrea. The lowest levels of metal were observed in muscles of fishes. Most of metals were detectable in the macro-plankton M. leidyi suggesting that this species could be used for water pollution monitoring, worldwide. Our results suggest the use of C. glucaum and A. vitrea as indicators of Ni and Cd contamination, respectively. B. improvisus has a high potential as an indicator for Zn and Cu pollution, while P. adspersus and P. maeoticus showed this capacity for Cu. This study provides a baseline for biomonitoring programs elsewhere in the Caspian Sea. Furthermore, the species C. glucaum and B. improvisus could be used for comparisons of metal contamination worldwide.
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Roya Mirzajani,Shokufeh Ahmadi 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.23 No.-
This paper presents a feasible protocol for the preparation of melamine conjugated Fe3O4 magnetic nanoparticles. The application of this magnetic nanocomposite as a novel and sensitive solid phase for removal, preconcentration and spectrophotometric determination of trace amount of malachite green (MG) was developed. Combination of nanocomposite adsorption and easily magnetic separation was used to extraction of MG. The calibration graph was linear in the range 0.1–8 mg mL1 of MG. The detection limit of the method for determination of MG was 0.05 mg mL1 with a relative standard deviation less than 1.66%.
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Vahidi, Sogand,Mirzajani, Ebrahim,Norollahi, Seyedeh Elham,Aziminezhad, Mohsen,Samadani, Ali Akbar KOREAN PHARMACOPUNCTURE INSTITUTE 2022 Journal of pharmacopuncture Vol.25 No.2
Gastric cancer (GC) is a significant cause of cancer mortality which has led to focused exploration of the pathology of GC. The advent of genome-wide analysis methods has made it possible to uncover genetic and epigenetic fluctuation such as abnormal DNA methylation in gene promoter regions that is expected to play a key role in GC. The study of gastric malignancies requires an etiological perspective, and Helicobacter pylori (H. pylori) was identified to play a role in GC. H. pylori infection causes chronic inflammation of the gastric epithelium causing abnormal polyclonal methylation, which might raise the risk of GC. In the last two decades, various pathogenic factors by which H. pylori infection causes GC have been discovered. Abnormal DNA methylation is triggered in several genes, rendering them inactive. In GC, methylation patterns are linked to certain subtypes including microsatellite instability. Multiple cancer-related processes are more usually changed by abnormal DNA methylation than through mutations, according to current general and combined investigations. Furthermore, the amount of acquired abnormal DNA methylation is heavily linked to the chances of developing GC. Therefore, we investigated abnormal DNA methylation in GC and the link between methylation and H. pylori infection.
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Mahmood Abedinzade,Mohammad Rostampour,Ebrahim Mirzajani,Zahra Bostani Khalesi,Tahere Pourmirzaee,Korosh Khanaki 대한약침학회 2019 Journal of pharmacopuncture Vol.22 No.4
Objectives: The aim of the present work is evaluating the special effects of Urtica Dioica and Lamium Album on the serum level of K-Ras and GSK-3 beta in diabetic rats. Methods: In the present experimental study, 32 male Wistar rats randomly divided into 4 groups (Group I:normal control rats; receiving daily PBS, Group 2: diabetic control rats; receiving single dose of streptozotocin (60 mg/kg) and daily PBS, Group 3: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of the U. dioica, Group 4: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of L. Album. Diabetes-induced by an intraperitoneal injection of streptozotocin (60 mg/ kg). On the 14 th day of treatment, the weight, fasting blood sugar (FBS) and on 28 th day blood glucose, K-Ras and GSK3 beta was measured. Results: In diabetic group blood GSK- 3 beta increase in comparison to control group (P < 0.05), also blood K-Ras decrease in the diabetic group (P < 0.05). Both extracts reduced GSK-3 beta level, however, this reduction was only statistically significant by U.dioica (P < 0.05). Compared to diabetic group, blood K-Ras level increased by both extract (P < 0.05). Also diabetes induction increase blood glucose levels and both extracts decrease its level significantly (P < 0.05).there is no significant differences among both extract effects on blood glucose, and K-Ras. Conclusion: For the first time shown that both extracts by regulating GSK-3 beta and K-Ras improve blood glucose level. More studies are needed to determine all the effects of these herbs.
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Epidemiologic and Socioeconomic Status of Bladder Cancer in Mazandaran province, Northern Iran
Ahmadi, Mohammad,Ranjbaran, Hossein,Amiri, Marzeih Momeninejad,Nozari, Jamshid,Mirzajani, Mohammad Reza,Azadbakht, Mohammad,Hosseinimehr, Seyed Jalal Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Background: Bladder cancer is one the most common malignancies of the genitourinary tract. The present study aimed to assess the epidemiology, of bladder cancer in Mazandaran, a large province in northern Iran as high-incidence cancer area, during a 2-year period. Methods: The data for this study were obtained from the population-based cancer registry of the Vice-Chancellory for Health Affairs of Mazandaran University of Medical Sciences and Mazandaran hospitals between March 1, 2010 and March 1, 2011. Demographic data, including sex, age, residency and symptoms were investigated through careful review of medical records. Using a questionnaire protocol, several variables were assessed for these cases such as smoking, history of opium, vegetable consumption habits, and history of other cancers. Results: A total of 112 cases were analyzed, 98 (87.5%) in men and 14 (12.5%) in women (mean age of $68.0{\pm}14.6$ years). Urban and rural residence were 60.7% and 39.3%. Tobacco and opium use were found in 45.5% and 21.4% of patients, respectively. Approximately 60% consumed vegetables an average of fewer than one time per day. Hematuria was the first symptom in these cases which were mainly diagnosed as having bladder cancer by ultrasonography. Conclusion: The results showed that bladder cancer tends to be found in the elderly and the male to female ratio is high. Macroscopic hematuria is a very important symptom for indicating probably urothelial tumor that should be followed up patients with transabdominal ultrasonography as a routine modality.
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