Direct ethanol production from dextran industrial waste water by Zymomonas mobilis

Ming-xiong He,Han Qin,Xiao-bo Yin,Zhi-yong Ruan,Fu-rong Tan,Bo Wu,Zong-xia Shui,Li-chun Dai,Qi-chun Hu 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.11

The direct production of ethanol from dextran industrial waste water was investigated by using Zymomonasmobilis via batch and semi-continuous fermentation mode. In batch fermentation, pretreated waste water (unsterilizedand sterilized), pH value (3.8 and 6.0), and Mg2+(with and without) was compared with OD600, sugar and ethanol con-centration. After 24 h fermentation, sugar in the dextran waste water was almost exhausted, and the amount of ethanolaccumulated reached 24.33-29.92 g/l, which is nearly 99% of the theoretical yield of ethanol. Kinetic parameters ofZ. mobilis in batch fermentation were also investigated. The raw dextran waste water was also used in semi-continuousfermentation. After 48 h fermentation, the production of ethanol was 28.65 g/l. These results indicated that dextranwaste water may be used as a candidate substrate and Z. mobilis could convert the raw material into ethanol directly.

Steel and FRP double-tube confined RAC columns under compression: Comparative study and stress-strain model

Ming-Xiang Xiong,Guangming Chen,Yue-Ling Long,Hairui Cui,Yaoming Liu 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.43 No.2

Recycled aggregate concrete (RAC) is rarely used in load-carrying structural members. To widen its structural application, the compressive behavior of a promising type of composite column, steel-fiber reinforced polymer (FRP) doubletube confined RAC column, has been experimentally and analytically investigated in this study. The objectives are the different performance of such columns from their counterparts using natural aggregate concrete (NAC) and the different mechanisms of the double-tube and single-tube confined concrete. The single-tube confined concrete refers to that in concrete-filled steel tubular (CFST) columns and concrete-filled FRP tubular (CFFT) columns. The test results showed that the use of recycled coarse aggregates (RCA) affected the axial load-strain response in terms of deformation capacity but such effect could be eliminated with the increasing confinement. The composite effect can be triggered by the double confinement of the steel and carbon FRP (CFRP) tubes but not by the steel and polyethylene terephthalate (PET) FRP tubes. The proposed analysis-oriented stress-strain model is capable to capture the load-deformation history of such steel-FRP double-tube confined concrete columns under axial compression.

Physiological and Pharmacological Characterization of Glutamate and GABA Receptors in the Retina

Xiong-Li Yang,Ying Shen,Ming-Hu Han,Tao Lu 대한생리학회-대한약리학회 1999 The Korean Journal of Physiology & Pharmacology Vol.3 No.5

<P> Glutamate and γ-aminobutyric acid (GABA) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, respectively. Using the whole-cell patch clamp technique and a rapid solution changer, glutamate and GABA receptors have been extensively investigated in carp retina. Glutamate receptors on both horizontal and amacrine cells may be an AMPA preferring subtype, which predominantly consists of flop splice variants. GABA<SUB>A</SUB> and GABA<SUB>C</SUB> receptors coexist in bipolar cells and they both show significant desensitization. Kinetics analysis demonstrated that activation, deactivation and desensitization of the GABA<SUB>C</SUB> receptor-mediated response of these cells are overall slower than those of the GABA<SUB>A</SUB> response. Endogenous modulator Zn<SUP>2⁢</SUP> in the retina was found to differentially modulate the kinetic characteristics of the GABA<SUB>C</SUB> and GABA<SUB>A</SUB> responses.

Effect of Vehicle-Bridge Interaction Vibration on Young Concrete

Xiong Zhang,Ming Zhao,Yong-juan Zhang,Zhou Lei,Yue-ran Zhang 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.1

The purpose of this investigation was to study the effect of vehicle-bridge interaction vibration on repairing concrete. A newlydeveloped systematic test was used to simulate the vibration and evaluate its effect. The results indicated that both external damageand internal damage were serious when the simulated vibration test was conducted during a special time period. And this special timeperiod was defined as the concrete disturbance sensitive period when the penetration resistance ranged from 3.5 MPa to 28 MPa. Anti-cracking fiber and self-healing admixture improved the vibration resistance of young concrete. When the dosage of anticrackingfiber came to 800 g/m3 by volume of concrete, the 3-day crack area on the concrete surface decreased over 50%. When 9%self-healing admixture was added to the concrete, the ultrasonic pulse velocity of concrete subjected to vibration was higher all thetime than without the admixture added. And the ultrasonic pulse velocity at the age of 28 days reached 95% of the control concretewhich suffered no vibration. Sand percentage and maximum aggregate size were found to significantly influence the vibrationresistance of concrete.

Parecoxib: an Enhancer of Radiation Therapy for Colorectal Cancer

Xiong, Wei,Li, Wen-Hui,Jiang, Yong-Xin,Liu, Shan,Ai, Yi-Qin,Liu, Rong,Chang, Li,Zhang, Ming,Wang, Xiao-Li,Bai, Han,Wang, Hong,Zheng, Rui,Tan, Jing Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

Background: To study the effect of parecoxib, a novel cyclooxygenase-2 selective inhibitor, on the radiation response of colorectal cancer (CRC) cells and its underlying mechanisms. Materials and Methods: Both in vitro colony formation and apoptosis assays as well as in vivo mouse xenograft experiments were used to explore the radiosensitizing effects of parecoxib in human HCT116 and HT29 CRC cells. Results: Parecoxib sensitized CRC cells to radiation in vitro with a sensitivity enhancement ratio of 1.32 for HCT116 cells and 1.15 for HT29 cells at a surviving fraction of 0.37. This effect was partially attributable to enhanced apoptosis induction by parecoxib combined with radiation, as illustrated using an in vitro apoptosis assays. Parecoxib augmented the tumor response of HCT116 xenografts to radiation, achieving growth delay more than 20 days and an enhancement factor of 1.53. In accordance with the in vitro results, parecoxib combined with radiation resulted in less proliferation and more apoptosis in tumors than radiation alone. Radiation monotherapy decreased microvessel density (MVD) and microvessel intensity (MVI), but increased the hypoxia level in xenografts. Parecoxib did not affect MVD, but it increased MVI and attenuated hypoxia. Conclusions: Parecoxib can effectively enhance radiation sensitivity in CRC cells through direct effects on tumor cells and indirect effects on tumor vasculature.

A Novel Single Phase Synchronous Reference Frame Phase-Locked Loop with a Constant Zero Orthogonal Component

Ming Li,Yue Wang,Xiong Fang,Yuan Gao,Zhaoan Wang 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6

A novel single phase Phase-Locked Loop (PLL) is proposed in this paper to accurately and rapidly estimate the instantaneous phase angle of a grid. A conjugate rotating vector pair is proposed and defined to synthesize the single phase signal in the stationary reference frame. With this concept, the proposed PLL innovatively sets one phase input of the PARK transformation to a constant zero. By means of a proper cancellation, a zero steady state phase angle estimation error can be achieved, even under magnitude and frequency variations. The proposed PLL structure is presented together with guidelines for parameters adjustment. The performance of the proposed PLL is verified by comprehensive experiments. Satisfactory phase angle estimation can be achieved within one input signal cycle, and the estimation error can be totally eliminated in four input cycles for the most severe conditions.

Characteristics of registered studies for Coronavirus disease 2019 (COVID-19): a systematic review

Ming Yang,Ya-xi Shang,Zi-yu Tian,Min Xiong,Chun-li Lu,Jiang Yue,Zhang Yao,Zhang Ying-ying,Jin Xin-yan,Jin Qiu-bai,Zhang Ying-ying,Willcox Merlin L.,Liu Jian-ping 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.3

Background: The World Health Organization characterized the Coronavirus disease 2019 (COVID-19) as a pandemic on March 11th. Many clinical trials on COVID-19 have been registered, and we aim to review the study characteristics and provide guidance for future trials to avoid duplicated effort. Methods: Studies on COVID-19 registered before March 3rd, 2020 on eight registry platforms worldwide were searched and the data of design, participants, interventions, and outcomes were extracted and analyzed. Results: Three hundred and ninety-three studies were identified and 380 (96.7%) were from mainland China, while 3 in Japan, 3 in France, 2 in the US, and 3 were international collaborative studies. Two hundred and sixty-six (67.7%) aimed at therapeutic effect, others were for prevention, diagnosis, prognosis, etc. Two hundred and two studies (51.4%) were randomized controlled trials. Two third of therapeutic studies tested Western medicines including antiviral drugs (17.7%), stem cell and cord blood therapy (10.2%), chloroquine and derivatives (8.3%), 16 (6.0%) on Chinese medicines, and 73 (27.4%) on integrated therapy of Western and Chinese medicines. Thirty-one studies among 266 therapeutic studies (11.7%) used mortality as primary outcome, while the most designed secondary outcomes were symptoms and signs (47.0%). Half of the studies (45.5%) had not started recruiting till March 3rd. Conclusion: Inappropriate outcome setting, delayed recruitment and insufficient numbers of new cases in China implied many studies may fail to complete. Strategies and protocols of the studies with robust and rapid data sharing are warranted for emergency public health events, helping the timely evidence-based decision-making.

Design of Switchable and Reconfigurable Semi-lumped Wideband Bandpass Filter

Yang Xiong,LiTian Wang,Wei Zhang,DouDou Pang,Fan Zhang,Ming He 한국전자통신연구원 2017 ETRI Journal Vol.39 No.5

A switchable single-wideband (SWB)-to-dual-wideband (DWB) bandpass filter (BPF), which is realized by using lumped switches, is presented in this paper. By alternating the operation modes—ON and OFF—in which the ON mode is achieved by placing the capacitors at the switching spots and the OFF mode is achieved by replacing the capacitors with inductors, DWB-to-SWB BPF can be achieved on the same device. In addition, by changing the capacitor values, the center frequency (CF) of the lower passband of DWB BPF can be easily tuned from 1.69 GHz to 2.22 GHz, while the higher passband stays almost unchanged. As an example, an SWB-to-DWB BPF is designed, fabricated, and measured. This BPF exhibits good performance including wideband, high isolation, compact size, and ability to switch.

Applying Beamforming to LTE Base Station for Reducing Interference Impact and Saving Frequency

Yan-Ming Cheng,Ye Wang,Il-Kyoo Lee,Zhen-Xiong Zhou 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.6

This paper assumes that Long Term Evolution (LTE) will be deployed in TV White Spaces (TVWSs). Beamforming is a technology that is applied to an LTE base station (BS) for reducing interference impact of LTE on DTV. A simulation method based on Monte Carlo is proposed to evaluate the interference probability in DTV receivers in the case of interference impact of LTE BS on DTV receiver. As per simulation results, the interference impact of LTE BS on DTV receiver is efficiently mitigated and the guard band remarkably reduced when LTE BS uses beamforming.

Prognostic value of preoperative neutrophil-to-lymphocyte ratio in histological variants of non-muscle-invasive bladder cancer

Deng-xiong Li,Xiao-ming Wang,Yin Tang,Yu-bo Yang,Dechao Feng,Ao Li,Fa-cai Zhang,Yun-jin Bai,Ping Han 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.6

Purpose: Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC). Materials and Methods: This retrospective study included patients with VH-NMIBC admitted at our center between January 2009 and May 2019. The best cut-off value of NLR was measured by the receiver operating characteristic curve and Youden index. The Kaplan-Meier method and Cox proportional hazard regression models were employed to evaluate the association between PNLR and disease prognosis, including recurrence-free survival (RFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS). Results: A total of 243 patients with VH-NMIBC were enrolled in our study. According to the Kaplan-Meier method results, patients with PNLR ≥2.2 were associated with poor RFS (p<0.001), PFS (p<0.001), CSS (p<0.001), and OS (p<0.001). Multivariable analyses indicated that PNLR ≥ 2.2 was an independent prognostic factor of RFS (hazard ratio [HR], 2.11; 95% confidence interval [CI, 1.57–1.83; p<0.001), PFS (HR, 2.34; 95% CI, 1.70–3.21; p<0.001), CCS (HR, 2.87; 95% CI, 1.96–4.18; p< 0.001), and OS (HR, 2.83; 95% CI, 1.96–4.07; p<0.001). Conclusions: This study identified that PNLR ≥2.2 was usually associated with a poor prognosis for patients with VH-NMIBC.