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MAKINO JUNICHIRO The Korean Astronomical Society 2005 Journal of The Korean Astronomical Society Vol.38 No.2
We overview the GRAPE (GRAvity piPE) project. The goal of the GRAPE project is to accelerate the astrophysical N-body simulations. Since almost all computing time is spent for the evaluation of the gravitational force between particles, we can greatly accelerate many N-body simulations by developing a specialized hardware for the force calculation. In 1989, the first such hardware, GRAPE-1, was completed, with the peak speed of 120 Mflops. In 2003, GRAPE-6 was completed, with the peak speed of 64 Tflops, which is nearly 106 times faster than GRAPE-l and was the fastest computer at that time. In this paper, we review the basic concept of the GRAPE hardwares, the history of the GRAPE project, and two ongoing projects, GRAPE-DR and Project Milkyway.
Evolution of Asthma Concept and Effect of Current Asthma Management Guidelines
Sohei Makino,Hironori Sagara 대한천식알레르기학회 2010 Allergy, Asthma & Immunology Research Vol.2 No.3
Concept of asthma has changed from symptom-complex or airway hypersensitivity to airway inflammation and airway remodeling. Based on this concept asthma management guidelines (JGL) has been developed in Japan. Death from asthma has decreased drastically since the publication of the guidelines, although it is still high in elderly population. Further works are expected for “zero-death” from asthma and for tighter control of airway inflammation and resultant airway remodeling.
( Yohsuke Makino ),( Hidekazu Suzuki ),( Toshihiro Nishizawa ),( Kaori Kameyama ),( Tadakazu Hisamatsu ),( Hiroyuki Imaeda ),( Makio Mukai ),( Toshifumi Hibi ) The Editorial Office of Gut and Liver 2010 Gut and Liver Vol.4 No.1
Reported herein is a case of mucosa-associated lymphoid tissue (MALT) lymphoma of the terminal ileum with a large-cell component, which regressed spontaneously. To the best of our knowledge, only five cases of spontaneously regressing MALT lymphoma have been reported in the English-language literature, and all of these cases were low-grade lymphomas. Spontaneous regression of a MALT lymphoma with a high-grade component is very rare. The present case suggests that MALT lymphoma cells have a reversible nature, even in the presence of a high-grade component. (Gut Liver 2010;4:117-121)