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Mostafa Maha,Hasanin Ahmed,Mostafa Mahmoud,Taha Mai Y,Elsayad Mohamed,Haggag Fatma Alzahraa,Taalab Omar,Rady Ashraf,Abdelhamid Bassant 대한마취통증의학회 2021 Korean Journal of Anesthesiology Vol.74 No.4
Background: Elderly population are at increased risk of spinal anesthesia-induced hypotension increasing their risk for postoperative morbidity and mortality. This study aimed to compare the hemodynamic effects of prophylactic infusion of norepinephrine (NE) versus phenylephrine (PE) in elderly patients undergoing hip fracture surgery under spinal anesthesia. Methods: Elderly patients scheduled for hip fracture surgery were randomized to receive either NE infusion (8 µg/min) (NE group, n = 31) or PE infusion (100 µg/min) (PE group, n = 31) after spinal anesthesia. Outcomes included mean heart rate, mean blood pressure, cardiac output, incidence of spinal anesthesia-induced hypotension, incidence of bradycardia, and incidence of hypertension. Results: Sixty-two patients with a mean age of 71 ± 6 years were included in the final analysis (31 patients in each group). The NE group showed a higher mean heart rate and cardiac output than the PE group. The NE group had a lower incidence of reactive bradycardia (10% vs. 36%, P = 0.03) and hypertension (3% vs. 36%, P = 0.003) than the PE group. No study participant developed hypotension, and the mean blood pressure was comparable between the two groups. Conclusions: Both NE and PE infusions effectively prevented spinal anesthesia-induced hypotension in elderly patients undergoing hip fracture surgery. However, NE provided more hemodynamic stability than PE; maintaining the heart rate, higher cardiac output, less reactive bradycardia, and hypertension.
Mostafa A. A. Mahmoud 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.4
The flow and heat transfer of an electrically conducting micropolar fluid on a continuously moving porous plate embedded in a non-Darcian porous medium in the presence of a transverse magnetic field and heat generation or absorption has been considered. Ohmic heating and a new model for viscous dissipation are taken into account. The transformed coupled non-linear ordinary differential equations are solved numerically by employing a fourth-order Rung-Kutta integration scheme coupled with the shooting technique. The effects of various physical parameters on the velocity, micro-rotation velocity and temperature are shown graphically. Moreover, the numerical values of the local skin-friction, the local wall couple stress and the local Nusselt number are displayed in a tabular form and are discussed.
Mostafa A.A. Mahmoud 한국산업응용수학회 2007 Journal of the Korean Society for Industrial and A Vol.11 No.1
The effects of variable viscosity, blowing or suction on mixed convection flow of a viscous incompressible fluid a semi-infinite horizontal flat plate aligned parallel to a uniform stream in the presence of the wall temperature distribution inversely proportional to the square root of the distance from the leading edge have been investigated. The equations governing the flow are transformed into a system of coupled non-linear ordinary differential equations by using similarity variables. The similarity equations have been solved numerically. The effect of the viscosity temperature parameter, the buoyancy parameter and the blowing or suction parameter on the velocity and temperature profiles as well as on the skin-friction coefficient and the Nusselt number are discussed.
Synthesis, structural, TD-DFT, and optical characteristics of indole derivatives
Almutlaq N.,Elshanawany Mahmoud M.,Sayed Mostafa,Younis Osama,Ahmed Mostafa,Wachtveitl Josef,Braun Markus,Tolba Mahmoud S.,Al-Hossainy Ahmed F.,Abozeed Amina A. 한국물리학회 2023 Current Applied Physics Vol.45 No.-
New compounds of (E)-1-(3-chloro-1H-indol-2-yl)-N-(4-methoxyphenyl)methanimine [Indol-M] and (E)-1-(4- (((3-chloro-1H-indol-2-yl)methylene)amino)phenyl)ethan-1-one [Indol-A] were synthesized and subsequently converted to thin films via physical vapor deposition technique. Numerous characterization techniques were used including FTIR, nuclear magnetic resonance, X-ray diffraction, scanning electron microscope, and optical spectroscopy. Additionally, the optimization using TD-DFTD/Mol3 and Cambridge Serial Total Energy Bundle (TD-FDT/CASTEP) was performed. The XRD and FTIR spectra recorded experimentally were confirmed by TD-DFT calculations, proving their molecular structure. As determined by XRD, the crystallite size of [Indol-M]TF and [Indol-A]TF is 72.26 and 62.05 nm, respectively. SEM image depicts a one-dimensional morphological structure made up of tightly packed nanorods. The direct optical energy bandgaps computed using Tauc’s equation for the [Indol-M]TF and [Indol-A]TF are 4.49 eV and 3.31 eV, respectively. As predicted by CASTEP TD-DFT, the optical properties agree well with the experimental values. [Indol-M]TF and [Indol-A]TF present good candidates for optoelectronics and solar cell applications.
Yacoub, Haitham Ahmed,Mahmoud, Wael Mahmoud,El-Baz, Hatim Alaa-Eldeen El-Din,Eid, Ola Mohamed,El-Fayoumi, Refaat Ibrahim,Mahmoud, Maged Mostafa,Harakeh, Steve,Abuzinadah, Osama H.A. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Aim and Objectives: This study investigated substitutions in the ATP synthase subunit 6 gene of mitochondrial DNA (mtDNA) as a potential diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Based on mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, approximately 465 bp of the ATP synthase subunit 6 gene were amplified and sequenced. Results: The sequencing revealed thirty-one mutations at 14 locations in ATP synthase subunit 6 of mtDNA in the ALL subjects. All were identified as single nucleotide polymorphisms (SNPs) with a homoplasmic pattern. The mutations were distributed between males and females. Novel haplotypes were identified in this investigation: haplotype (G) was recorded in 34% in diagnosed subjects; the second haplotype was (C) with frequency of 13% in ALL subjects. Neither of these were observed in control samples. Conclusions: These haplotypes were identified for the first time in acute lymphoblastic leukemia patients. Five mutations able to change amino acid synthesis for the ATP synthase subunit 6 were associated with acute lymphoblastic leukemia. This investigation could be used to provide an overview of incidence frequency of acute lyphoblastic leukemia (ALL) in Saudi patients based on molecular events.
A New Septum in the Female Breast
Mostafa Abdel Rahman Awad,Mahmoud Magdi Sherif,Eaman Yahya Sadek,Hesham Aly Helal,Wafaa Raafat Abdel Hamid 대한성형외과학회 2017 Archives of Plastic Surgery Vol.44 No.2
Background Understanding the female breast fascial system is of paramount importance in breast surgery. Little was written about breast ligaments. Most articles refer to Cooper’s work without further anatomical studies. Lately, a horizontal septum has been described conveying nerves and vessels to the nipple areola complex. Methods During the surgical dissection of the lower part of the breast, in supero-medial technique for breast reduction operations, a fascial septum between the lower two quadrants was detected. This fibrous septum was studied through anatomic dissection of breast tissues during routine breast reshaping procedures that was done on 30 female patients. Magnetic resonance imaging (MRI) was performed preoperatively in all cases and correlated with the intraoperative findings. In the other five cases, outside the clinical study, the imaging was done during routine investigation for breast swellings. Results A vertical septum was identified in the lower part of the breast, lying at the breast meridian between the two lower quadrants. It is a tough bi-laminated structure that extends from the middle of the infra-mammary crease caudally to nipple-areola complex cranially and from the pectoral fascia posteriorly to the overlying skin anteriorly. This was proved by MRI findings. Conclusions This study describes a new inferior vertical septum which separates the lower half of the breast into two definite anatomical compartments: medial and lateral.
Application of the GTN model to predict the forming limit diagram of IF-Steel
Mahmoud Abbasi,Mohammad A. Shafaat,Mostafa Ketabch,Davoud F. Haghshenas,Mohammad Abbasi 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.2
Forming limit diagrams (FLDs) are extensively used in industries, particularly the auto industry. The establishment of these diagrams using a predictive approach can lead to reduction in both cost and time. In the present work, Gurson-Tvergaard-Needleman (GTN), a porosity-based model, was used to predict the FLD of an interstitial-free steel via finite element simulation. Optimum values of the GTN model were obtained by applying a response surface methodology (RSM) based on central composite design. Results show that RSM is a good method for an appropriate determination of the GTN model parameters, such as initial void volume fraction, effective void volume fraction, critical void volume fraction, and final void volume fraction. Furthermore, the experimental FLD of the specimen steel was considerably predicted using the obtained GTN model parameters.