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        Comparison of cecal microbiota composition in hybrid pigs from two separate three-way crosses

        Yang, Yuting,Shen, Liyan,Gao, Huan,Ran, Jinming,Li, Xian,Jiang, Hengxin,Li, Xueyan,Cao, Zhenhui,Huang, Ying,Zhao, Sumei,Song, Chunlian,Pan, Hongbin Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.7

        Objective: The intestinal microbiota plays an important role in host physiology, metabolism, immunity, and behavior. And host genetics could influence the gut microbiota of hybrid animals. The three-way cross model is commonly utilized in commercial pig production; however, the use of this model to analyse the gut microbial composition is rarely reported. Methods: Two three-way hybrid pigs were selected, with Saba pigs as the starting maternal pig: Duroc× (Berkshire×Saba) (DBS) pig, Berkshire×(Duroc×Saba) (BDS) pig. One hundred pigs of each model were reared from 35 days (d) to 210 d. The body weight or feed consumption of all pigs were recorded and their feed/gain (F/G) ratio was calculated. On day 210, 10 pigs from each three-way cross were selected for slaughter, and cecal chyme samples were collected for 16S rRNA gene sequencing. Results: The final body weight (FBW) and average daily gain (ADG) of DBS pigs were significantly higher than those of BDS pigs (p<0.05), while the F/G ratios of DBS pigs were significantly lower than those of BDS pigs (p<0.05). The dominant phyla in DBS and BDS pigs were Bacteroidetes (55.23% vs 59%, respectively) and Firmicutes (36.65% vs 34.86%, respectively) (p>0.05). At the genus level, the abundance of Prevotella, Roseburia, and Anaerovibrio in DBS pigs was significantly lower than in BDS pigs (p<0.01). The abundance of Eubacterium, Clostridium XI, Bacteroides, Methanomassiliicoccus, and Parabacteroides in DBS pigs was significantly higher than in BDS pigs (p<0.05). The FBWs and ADGs were positively correlated with Bacteroides, ClostridiumXI, and Parabacteroides but negatively correlated with the Prevotella, Prevotella/Bacteroides (P/B) ratio, Roseburia, and Anaerovibrio. Conclusion: These results indicated that host genetics affect the cecal microbiota composition and the porcine gut microbiota is associated with growth performance, thereby suggesting that gut microbiota composition may be a useful biomarker in porcine genetics and breeding.

      • KCI등재

        Epidemiology, Characteristics, and Prognostic Factors of Primary Atypical Teratoid/Rhabdoid Tumors in the Spinal Canal: A Systematic Review

        Zhibin Li,Yubo Wang,Liyan Zhao,Yunqian Li 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

        Primary atypical teratoid/rhabdoid tumors (AT/RTs) in the spinal canal are rare central nervous system (CNS) neoplasms that are challenging to diagnose and treat. To date, there has been no standard treatment regimen for these challenging malignant tumors. Thus, we conducted this research to explore potential prognostic factors and feasible treatment modalities for improving the prognosis of these tumors. Articles were retrieved from the PubMed, MEDLINE, and Embase databases, using the keywords “atypical teratoid/rhabdoid tumor,” “rhabdoid tumor,” “spine,” “spinal,” “spinal neoplasm”, and “spinal cord neoplasm.” All eligible cases demonstrated SMARCB1-deficient expression validated by pathological examination. We collected and analyzed data related to clinical presentation, radiological features, pathological characteristics, treatment modalities and prognosis via Kaplan-Meier and Cox regression analyses. Thirty-six articles comprising 58 spinal AT/RT patients were included in the study. The median progression-free survival (PFS) and overall survival (OS) were 18 and 22 months, respectively. Kaplan-Meier analysis demonstrated significant survival improvements for OS in the nonmetastasis, male, radiotherapy and intrathecal chemotherapy groups as well as for PFS in the chemotherapy and radiotherapy groups. Multivariate analysis revealed that chemotherapy and radiotherapy were prognostic factors for improved PFS, and that intrathecal chemotherapy reduced the risk of mortality. Spinal AT/RTs are uncommon malignant entities with a dismal survival rate. Although our review is limited by variability between cases, there is some evidence revealing potential risk factors and the importance of systematic chemotherapy, intrathecal chemotherapy and radiotherapy in spinal AT/RT treatment modalities.

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        Modeling and Regulator Design for Three-Input Power Systems with Decoupling Control

        Li, Yan,Zheng, Trillion Q.,Zhao, Chuang,Chen, Jiayao The Korean Institute of Power Electronics 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.6

        In hybrid renewable power systems, the use of a multiple-input dc/dc converter (MIC) leads to simpler circuit and lower cost, when compared to the conventional use of several single-input converters. This paper proposed a novel three-input buck/boost/buck-boost converter, which can be used in applications with various values of input voltage. The energy sources in this converter can deliver power to the load either simultaneously or individually in one switching period. The steady relationship, the power management strategy and the small-signal circuit model of this converter have been derived. With decoupling technology, modeling and regulator design can be obtained under multi-loop control modes. Finally, three generating methods of a multiple-input buck/boost/buck-boost converter is given, and this method can be extended to the other multiple-input dc/dc converters.

      • Improvement of SVM Image Reconstruction Algorithm in ECT System

        Li Yan,Song Haifeng,Zhang Guangwu,Chen Deyun,Wang Zhao,Cui Peng 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.3

        Due to the problem of low imaging accuracy and slow imaging speed when applying SVM image reconstruction algorithm in ECT system to dealing with a large amount of sample data set, the method of combining feature dimension reduction with SVM algorithm is proposed. This method classifies the sample data by using the way of clustering and extracts the feature parameter, finds out the connection between each sample and the feature, and deals the sample data with dimension reduction, thus finally getting the high-quality training sample. Then it trains the simplified sample data by applying SVM algorithm and obtains decision function, then the decision function is used to predict and image. The experimental results of image reconstruction show that this method greatly reduces the running time and improves the accuracy of imaging compared to using the SVM algorithm alone.

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