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- 저자 : Lingchen Yang (검색결과 3 건)
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Hongkang Zhao,Yaping Dai,Jun Yang,Youzhen Fang,Chengjie Mi,Lingchen Yang,Guojian Li 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.6
The seismic performance of precast reinforced concrete structures has long been a source ofconcern that impedes their use in seismic regions and high-rise buildings. To further optimizethe reinforcement configuration and enhance the seismic performance of the superimposedslab shear wall structures, this research proposed a superimposed slab shear wall withinnovative construction details. Five innovative superimposed slab shear walls and one cast-inplaceconcrete shear wall were designed and tested under low cycle lateral load. The effect ofaxial compression was considered during tests and analyses as well. In this paper, the seismicperformance, including failure mode, hysteretic behavior, load-bearing capacity, lateralstiffness degradation, energy dissipation, and seismic ductility was investigated and analyzed. The experimental results showed that five innovative superimposed slab shear walls and onecast-in-place concrete shear wall exhibited a similar failure mode of flexural-shear failure, anda large area of concrete was damaged and crushed at the shear wall corner. However, the areaof crushing concrete in the cast-in-place concrete shear wall was relatively small. And the areaof crushing concrete in the superimposed slab shear walls increased with the axial compressionratio. For the superimposed slab shear walls, the development of concrete cracks decreasedgradually with the enlargement in the axial compression ratio, while the length of the cracksincreased in this respect. The results indicated that innovative superimposed slab shear wallshad a higher strength capacity and lower lateral-resistant stiffness than the cast-in-placeconcrete shear wall. With the enlargement in the axial compression ratio, the peak strengthcapacity of the superimposed slab shear wall increased obviously, while it degraded rapidlyafter the peak load. It is suggested that the contribution of axial compression to the shear resistcapacity of the inclined section should not be considered in practical design. Meanwhile, theductility coefficients of the six specimens were larger than 2.2, which was in accordance withthe seismic requirements. This investigation could provide effective experimental data forfuture structural seismic performance evaluations and applications of precast superimposedslab shear wall structures.
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Ling Chen,Wen-jun Xiao,Qiong-xian Yan,Zhi-hua Gong,Sheng Zhang,Li Zeng,Ming Yang,Yan-he Zhou 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.8
The aim of this study is to evaluate the antiinflammatory and protective eff ects of L -theanine in infl ammatorybowel disease (IBD) and to identify the underlyingmolecular mechanisms. Rats were pre-treated with L -theanineat 0, 50, 200, or 800 mg/kg/day. IBD was induced inrats using dextran sulfate sodium (DSS). Histopathologicalanalysis suggests that L -theanine can suppress DSS-inducedIBD with signifi cant inhibition of infl ammation in large andsmall intestinal tissues. Moreover, the 200 mg/kg/day L -theanine-treated DSS group had higher body and small intestineweights, a lower disease activity index and expression ofinfl ammatory factors than the DSS group without pre-treatment. In RNA sequencing and tandem mass tag labelinganalyses, large number of mRNAs and proteins expressionlevel diff ered when compared with the DSS-induced ratswith and without 200 mg/kg/day L -theanine pre-treatment. Moreover, Kyoto Encyclopedia of Genes and Genomes pathwayanalysis indicates the anti-infl ammatory activities ofL -theanine in DSS-induced IBD, with a high representationof genes in “Cholesterol metabolism” and “Retinol metabolism”pathways. Analysis of protein–protein interaction networksfurther indicates the involvement of these two pathways. These studies suggest that medium-dose L -theaninepre-treatment could ameliorate DSS-induced IBD throughmolecular mechanisms involving cholesterol and retinolmetabolism.
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Case Reports : Sturge-Weber Syndrome
( Ling Chen ),( Jin Jin Wu ),( Min Hui Xu ),( Nian Chen ),( Ya Dong Yang ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.4
Sturge-Weber syndrome (SWS) is a neurocutaneous syndrome, characterized by the association of facial port-wine hemangiomas in the trigeminal nerve distribution area, with vascular malformation(s) of the brain (leptomeningeal angioma) with or without glaucoma. Herein, we reported Sturge-Weber syndrome in a 50-year-old man, who presented port-wine hemangiomas and epilepsy. In this case, the patient`s epilepsy episodes from his first year of life had been ignored and separated from the entity of SWS by his physicians, which led to delayed treatment. This case illustrates the importance of careful examination of patients of any age with hemangiomas in the trigeminal nerve with concomitant episodes of epilepsy. In such cases, there should be yearly neuroimaging screenings to guaranteed early interdisciplinary interventions from the time of definite diagnosis. (Ann Dermatol 23(4) 551~553, 2011)
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