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고등학교 학생들의 성에 관한 인식과 성교육에 대한 요구 조사 연구
남선영,정연강,박경숙,김화자 韓國學校保健學會 1995 韓國學校保健學會誌 Vol.8 No.2
A survey has conducted on two hundred high school students of the first and second grade by way of questionnaine in Seoul. The purpose of this study on the information from the survey is to cstimate the level of awareness and probe how they feel and what they wish on sex. X2 inspection is designed to assess general aspects of responded contents by way of percentage and examine degree of satisfaction on previously experienced sex education and demand for sex cducation. The result is as follows. 1. As a result of the examination of degree of awareness on sex of respondents, 62% delines sex as human relationship including moral values for harmony between men and women. 64% of the men and 70% of the women say that sex is a natural thing. It comes to the conclusion that most of the respondent sgenerally consider sex positive. On chastity, 68.5% of the respondent answer that it means physical chastity, 12.5% that chastity before marriage should be kept, and 43% that it should be kept as far as possible. Most of them pespond that it should be kept. 2. As a result of the examination on the contents of sex, they answer they know well in the order of masturbation(72%), pregnancy(76%), and sex(63%). Contraception, abortion and ejection are contents they poorly informed of. 3. As a result of the examination on expericncdc of sex education, 83% of men and 100% of women have experienced sex, education, but their degreeof satisfaction to it is very low. And 49% of the whole is dissatisfactory to it. There is some difference between male and female students.(p=0.000) That result translatcs that fcmale studeuts are educated on sex tjhrough more systematic subjects than male ones. In addition, it turns out that teenagers get most information on sex through friends, seniors, and mass media such as vidcos, TV and radios. Correct and systematic sex education is need because wrong information on sex culd be taught and bring them to misbehave. 4. 87.5% of the respondents answer that sex education is necessary, so that degree of necessity for sex education, turns out to be very high. Also the main subject that should perform sex education is in the order of school(50%), Society(24.5), home(18.5%). They respond that most appropriated period for the beginning of sex education is about elementary school age(43%), and 34% believes it to be put ahcad of elementary school age. Anurse teacher accounts for 54% for the main subject that addresses sex education, to male students visit teachers are most favored for 50%. As a result of those, it could be concluded that most high school students want sex education from responsible persons who have systematic and professional knowledge on sex. 5. In order to perform proper sex education by the above results, better educational effects are obtained when characteristics and natures of teenagers are known and most wanted knowledge by them is taught in priority in times of planning sex education. Besides, the contents of sex education suitable for each school should be planned before elementary school age and sex education should be performed in accordance with students' demand. In addition, sex education should be attentively performed by home, all organizations of socicty as well as school. Therefore, sex education will play a great role in making teenagers reestablish their conception on sex when the traditional and moral value systems of our country and the new value systems which are being formed under the influcnce of the western culture are in harmony.
Kang, Kyong-Hwa,Qian, Zhong-Ji,Ryu, BoMi,Karadeniz, Fatih,Kim, Daekyung,Kim, Se-Kwon The Korean Society of Food Science and Nutrition 2013 Preventive Nutrition and Food Science Vol.18 No.2
In this study, novel peptides (NIPP-1, NIPP-2) derived from Navicula incerta (microalgae) protein hydrolysate were explored for their inhibitory effects on collagen release in hepatic fibrosis with the investigation of its underlying mechanism of action. TGF-${\beta}1$ activated fibrosis in LX-2 cells was examined in the presence or absence of purified peptides NIPP-1 and NIPP-2. Besides the mechanisms of liver cell injury, protective effects of NIPP-1 and NIPP-2 were studied to show the protective mechanism against TGF-${\beta}1$ stimulated fibrogenesis. Our results showed that the core protein of NIPP-1 peptide prevented fibril formation of type I collagen, elevated the MMP level and inhibited TIMP production in a dose-dependent manner. The treatment of NIPP-1 and NIPP-2 on TGF-${\beta}1$ induced LX-2 cells alleviated hepatic fibrosis. Moreover, ${\alpha}$-SMA, TIMPs, collagen and PDGF in the NIPP-1 treated groups were significantly decreased. Therefore, it could be suggested that NIPP-1 has potential to be used in anti-fibrosis treatment.
Kyong-Hwa Kang,Zhong-Ji Qian,BoMi Ryu,Fatih Karadeniz,Daekyung Kim,Se-Kwon Kim 한국식품영양과학회 2013 Preventive Nutrition and Food Science Vol.18 No.2
In this study, novel peptides (NIPP-1, NIPP-2) derived from Navicula incerta (microalgae) protein hydrolysate were explored for their inhibitory effects on collagen release in hepatic fibrosis with the investigation of its underlying mechanism of action. TGF-β1 activated fibrosis in LX-2 cells was examined in the presence or absence of purified peptides NIPP-1 and NIPP-2. Besides the mechanisms of liver cell injury, protective effects of NIPP-1 and NIPP-2 were studied to show the protective mechanism against TGF-β1 stimulated fibrogenesis. Our results showed that the core protein of NIPP-1 peptide prevented fibril formation of type I collagen, elevated the MMP level and inhibited TIMP production in a dose-dependent manner. The treatment of NIPP-1 and NIPP-2 on TGF-β1 induced LX-2 cells alleviated hepatic fibrosis. Moreover, α-SMA, TIMPs, collagen and PDGF in the NIPP-1 treated groups were significantly decreased. Therefore, it could be suggested that NIPP-1 has potential to be used in anti-fibrosis treatment.
Antiproliferative Effect of Novel Chitin Benzoates on Human Cervical Cancer (HeLa) Cells
( Kyong Hwa Kang ),( Mustafa Zafer Karagozlu ),( Mi Seon Song ),( Jayachandran Venkatesana ),( Duck Hee Lee ),( Kyu Yun Chai ),( Se Kwon Kim ) 한국키틴키토산학회 2014 한국키틴키토산학회지 Vol.19 No.4
In this study, chitin and benzoic acid were conjugated by chemical methods to improve its solubility and bioactivity. The synthesis and conjugation of the chitin benzoate confirmed by FT-IR and 1 H-NMR spectra. Chitin benzoate induced cell death was further characterized by cell viability, changes in nuclear morphology and cell morphology. Significant inhibition on the cell proliferation of HeLa (human cervical adenocarcinoma) cells was observed by the effect of chitin benzoates in a dose-dependent manner. Moreover, protein and gene expression levels of the apoptosis pathway regulators such as caspase-8, Fas, FasL and Fasassociated death domain (FADD) were examined using RT-PCR and Western blot analyses. The exposure of synthesized chitin benzoate induced the apoptotic mechanism in HeLa cells via the stimulation of extrinsic pathway receptors. Therefore, the present results suggest that chitin benzoates have promising potential to use them as valuable anticancer agents.
강경화(Kyong-Hwa Kang) 한국콘텐츠학회 2018 한국콘텐츠학회논문지 Vol.18 No.11
본 연구의 목적은 알코올중독 예방을 위한 조기개입 프로그램이 성인 문제음주자의 알코올지식, 음주결과기대 및 음주거절효능감에 미치는 효과를 평가한 후 현장 적용 가능성을 살펴보는데 있다. 본 연구는 비동등성 대조군 전․후 설계를 이용한 유사실험연구이며, 연구 대상은 현재 직업을 유지중인 남성 중 알코올사용장애 선별 검사(AUDIT) 결과상 12-25점이다. 조기개입 프로그램 참여자는 실험군 13명, 대조군 12명 총 25명으로 실험군은 4회기 조기개입 프로그램에 참여하였고, 대조군은 알코올 자료집만 제공받았다. 통계분석은 Chi-square test, t-test, Mann-Whitney U test를 활용하였다. 조기개입 프로그램에 참여한 실험군은 대조군보다 알코올지식(t=1.258, p= .002), 부정적 음주결과기대(t=-1.346, p= .042) 및 음주거절효능감(t=2.817, p= .010)이 유의하게 증가되었다. 향후 문화적 특성을 고려한 문제음주자 선정 기준의 적용, 참여자 모집과 동기면담을 활용한 동기증진 개입이 필요할 것이다. 특히 문제음주에 대한 인식을 제고하기 위하여 웹 기반 알코올정보 제공 프로그램도 도움이 될 것이다. 문제음주자가 쉽게 접근할 수 있는 지역사회 현장에서 조기개입 프로그램이 적용되기를 기대한다. The aim of this study was to investigate the short term effects of early intervention on alcohol knowledge, alcohol expectancies, drinking refusal self-efficacy for alcoholism prevention in adults and to examine its applicability in the field. This study was a non-equivalent control group pre-post quasi-experimental design. The participants were currently working, and were 12-25 points on result of the Alcohol Use Disorders Identification Test(AUDIT). The participants were a total of 25 men: 13 in the intervention group and 12 in the control group. The intervention group participated in early intervention program once a week for 4 weeks and the control group received only a booklet of alcohol related information. A chi-square test, t-test, Mann-Whitney U test were analyzed by using IBM SPSS Statistics 20.0. The intervention group had significantly higher the alcohol knowledge(t=1.258, p= .002), the negative alcohol expectancies(t=-1.346, p= .042), and the drinking refusal self-efficacy(t=2.817, p= .010) than the control group. In the future, it is need to apply the criteria of problem drinkers considering cultural characteristics, recruitment of participants, and motivational enhancement intervention using motivational interviewing. Especially, web-based alcohol related information providing program will help raise awareness of problem drinking. Early intervention program needs to be applied in community settings where problem drinkers are easily accessible.