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오늘 본 자료
Mohammad Khaksari,Gholamreza Asadikaram,Amir Rahnema,Mehdi Mahmoodi,Gholamhosein Hasanshahi,Mohammad Hashemi,Mohammad Khaksari 대한약리학회 2011 The Korean Journal of Physiology & Pharmacology Vol.15 No.6
It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats. This experimental study was performed on normal, opium-addicted, diabetic and diabetic opium-addicted male and female rats. Apoptosis was evaluated by TUNEL and DNA fragmentation assays. Results of this study showed that apoptosis in opium-addicted and diabetic opium-addicted brain and liver cells were significantly higher than the both normal and diabetic rats. In addition, we found that apoptosis in brain cells of opium-addicted and diabetic opium-addicted male rats were significantly higher than opium-addicted and diabetic opium-addicted female, whereas apoptosis in liver cells of opium-addicted and diabetic opium-addicted female rats were significantly higher than opium-addicted and diabetic opium-addicted male. Overall, these results indicate that opium probably plays an important role in brain and liver cells apoptosis, therefore, leading neurotoxicity and hepatotoxicity. These findings also in away possibly means that male brain cells are more susceptible than female and interestingly liver of females are more sensitive than males in induction of apoptosis by opium.
SOME RESULTS ON PP AND PF-MODULES
KHAKSARI, AHMAD 호남수학회 2006 호남수학학술지 Vol.28 No.3
For a commutative ring with unity R, it is proved that R is a PF-ring if and only if the annihilator, $ann_R(a)$, for each $a{\in}R$ is a pure ideal in R. Also it is proved that the polynomial ring, R[x], is a PF-ring if and only if R is a PF-ring. Finally, we prove that M as an R-module is PF-module if and only if M[x] is a PF R[x]-module. Also M is a PP R-module if and only if M[x] is a PP R[x]-module.
Asiabanha, Majid,Asadikaram, Gholamreza,Rahnema, Amir,Mahmoodi, Mehdi,Hasanshahi, Gholamhosein,Hashemi, Mohammad,Khaksari, Mohammad The Korean Society of Pharmacology 2011 The Korean Journal of Physiology & Pharmacology Vol.15 No.6
It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats. This experimental study was performed on normal, opium-addicted, diabetic and diabetic opium-addicted male and female rats. Apoptosis was evaluated by TUNEL and DNA fragmentation assays. Results of this study showed that apoptosis in opium-addicted and diabetic opium-addicted brain and liver cells were significantly higher than the both normal and diabetic rats. In addition, we found that apoptosis in brain cells of opium-addicted and diabetic opium-addicted male rats were significantly higher than opium-addicted and diabetic opium-addicted female, whereas apoptosis in liver cells of opium-addicted and diabetic opium-addicted female rats were significantly higher than opium-addicted and diabetic opium-addicted male. Overall, these results indicate that opium probably plays an important role in brain and liver cells apoptosis, therefore, leading neurotoxicity and hepatotoxicity. These findings also in away possibly means that male brain cells are more susceptible than female and interestingly liver of females are more sensitive than males in induction of apoptosis by opium.