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Xin Wen,Yanlin Jing,Zhiping Hu,Jigang Shao,Jieru Li,Rui Wang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.12
It is of great importance to study the behavior of loess moisture infiltration based on the loess permeability velocity to prevent geological disasters by loess collapsibility and get effective solutions for the problems of practical engineering. In this study, a custom-made permeation device was used to measure the permeation velocity of collapsible loess before and after water immersion and consolidation. The infiltration characteristics of the undisturbed collapsible loess under different consolidation pressures were discussed, and the influence of the pore characteristics on the permeability velocity was analyzed by the mercury injection test. Meanwhile, the correlations of various types of pores on the permeability velocity were studied by the gray relational entropy method to further reveal the water infiltration mechanism in loess. The results showed that the soil is compressed after consolidation and immersion tests, and the pore volume and pore diameter decreases. However, permeability velocity increases rather than decreases, and the self-weight collapsible state has the most significant permeability velocity. To the collapsible loess, the permeability velocity decreases with the increase of soil pore area. Additionally, small pores show the strongest correlation with permeability velocity. The conclusions of this study have a positive role in guiding foundation treatments and slope stability in collapsible loess areas.
Jing-Guang Lu,Yingwei Wang,Ming-Rong Yang,Cai-Yun Wang,Jieru Meng,Jiazheng Liu,Zifeng Yang,Kongsong Wu,Li-Ping Bai,Guo-Yuan Zhu,Zhi-Hong Jiang 대한약학회 2022 Archives of Pharmacal Research Vol.45 No.9
(±)-Decumicorine A ( 1 ) and (±)- epi -decumicorine A ( 2 ), two pairs of enantiomeric isoquinoline alkaloids featuring a novel phenylpropanoid-conjugated protoberberine skeleton, were isolated and purifi ed from the rhizomes of Corydalis decumbens . The separation of (±)- 1 and (±)- 2 was achieved by chiral HPLC to produce four optically pure enantiomers. The structures and absolute confi gurations of compounds (−)- 1 , (+)- 1 , (−)- 2 , and (+)- 2 were elucidated by spectroscopic analysis, ECD calculations, and X-ray crystallographic analyses. The two racemates were generated from a Diels-Alder [4 + 2] cycloaddition between jatrorrhizine and ferulic acid in the proposed biosynthetic pathways, which were fully verifi ed by a biomimetic synthesis. Moreover, compound (+)- 1 exhibited an antiviral entry eff ect on SARS-CoV-2 pseudovirus by blocking spike binding to the ACE2 receptor on HEK-293T-ACE2 h host cells.