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- 저자 : Jianqiang Shi (검색결과 3 건)
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Development and Challenges for Power Battery in Electric Ship
Jianqiang Shi,Guichen Zhang,Run Lu,Mengwei Chen 국제이네비해양경제학회 2022 International Journal of e-Navigation and Maritime Vol.18 No.1
With the continuous prosperity and development of the marine industry, the number of ships is increasing while greenhouse gas emissions are rising. In order to meet the relevant international ship emission regulations, the solution of developing electric ships is proposed. As the core device of the electric ship propulsion system, the maturity and applicability of power battery technology play a key role in the development of the electric ship. This article introduces the principles and advantages of the fuel cell, lithium-ion battery as well as supercapacitor battery, respectively, and analyzes the application status and challenges of power batteries in existing electric ships. The development direction and problems to be solved of power battery in current and future ship applications are put forward, which can provide a reference for further research.
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Jianhui Zhang,Jun Ge,Juyin Li,Jianqiang Li,Yong Zhang,Yinghui Shi,Jiaojiao Sun,Qiongjin Wang,Xiaobo Zhang,Xing-xu Zhao 대한수의학회 2023 Journal of Veterinary Science Vol.24 No.1
Background: Inactivated vaccines are limited in preventing foot-and-mouth disease (FMD) due to safety problems. Recombinant virus-like particles (VLPs) are an excellent candidate for a novel vaccine for preventing FMD, given that VLPs have similar immunogenicity as natural viruses and are replication- and infection-incompetent. Objectives: The 3C protease and P1 polyprotein of type O FMD virus (FDMV) was expressed in yeast Hansenula polymorpha to generate self-resembling VLPs, and the potential of recombinant VLPs as an FMD vaccine was evaluated. Methods: BALB/c mice were immunized with recombinant purified VLPs using CpG oligodeoxynucleotide and aluminum hydroxide gel as an adjuvant. Cytokines and lymphocytes from serum and spleen were analyzed by enzyme-linked immunosorbent assay, enzyme-linked immunospot assay, and flow cytometry. Results: The VLPs of FMD were purified successfully from yeast protein with a diameter of approximately 25 nm. The immunization of mice showed that animals produced high levels of FMDV antibodies and a higher level of antibodies for a longer time. In addition, higher levels of interferon-γ and CD4+ T cells were observed in mice immunized with VLPs. Conclusions: The expression of VLPs of FMD in H. polymorpha provides a novel strategy for the generation of the FMDV vaccine.
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( Xinqiang Zhu ),( Gang Zhou ),( Peng Ni ),( Xuetong Jiang ),( Hailong Huang ),( Jianqiang Wu ),( Xiaohong Shi ),( Xiaoling Jiang ),( Jianing Liu ) 대한소화기학회 2021 Gut and Liver Vol.15 No.2
Background/Aims: Colorectal cancer (CRC) patients often exhibit peritoneal metastasis, which negatively impacts their prognosis. CD31 and D2-40 have recently been suggested to be predictors of breast cancer prognosis, but their role in colorectal peritoneal metastasis (CRPM) remains unknown. Methods: The expression profiles of CD31 and D2-40 were analyzed in CRC patients with or without CRPM and in CRC cell lines with increasing metastatic potential. Overexpression and short hairpin RNA knockdown assays were performed in CRC cells, and the effects of these alterations on epithelial-mesenchymal transition (EMT) in vitro, growth of xenograft tumors in vivo, and peritoneal metastasis potential in a mouse model of CRPM were examined. Results: The expressions of CD31 and D2-40 were upregulated in CRC tumor tissues and was elevated further in tumor tissues from patients with CRPM. CD31 and D2-40 expression levels exhibited increasing trends parallel to the EMT potential of CRC cells. CD31 and D2-40 are essential for CRC cell EMT in vitro as well as for xenograft tumor growth and peritoneal metastasis in vivo. Conclusions: CD31 and D2-40 contribute to CRPM by promoting EMT and may serve as prognostic markers and therapeutic targets for CRC, particularly in patients with peritoneal metastasis. (Gut Liver 2021;15:273-283)
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