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      • Sinter-hardening Process of P/M Steels and its Recent Developments

        Yi Jianhong,Ye Tuming,Peng Yuandong,Xia Qinglin,Wang Hongzhong 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        The mechanical properties of ferrous powder metallurgy (P/M) materials are directly related to their microstructure. Ferrous P/M materials with sufficient hardenability will develop microstructures containing significant percentages of martensite in the as-sintered condition. Recently, sinter-hardening has developed into a highly cost effective production method through hardened P/M parts without the need for additional heat-treatments. This paper reviews the advances of sinter-hardening as well as some key processing parameters such as sintering temperature, cooling rate, tempering required to produce high quality sinter-hardened components. Specific topics including effect of alloying elements, alloying methods, and the Characterization and observation of microstructure are discussed.

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        Numerical Modelling of the Creep Subsidence of an Ocean Lighthouse Constructed on a Reclaimed Coral Reef Island

        Dawei Yu,Jianhong Ye 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.4

        This work is to investigate the creep subsidence of a large-scale ocean lighthouse constructed on a reclaimed calcareous coral sand foundation (abbreviated to RCCSF thereafter) in the South China Sea (SCS). Firstly, two modified Burgers creep models, referred to as modified HBM and KBM, respectively, are proposed and validated based on several triaxial creep test results, and then both are implanted into ABAQUS. Secondly, the model parameters of the modified Huang’s Burgers Creep Model (HBM) and Kong’s Burgers Creep Model (KBM) for the RCCSF are carefully calibrated for the subsequent numerical modelling according to the creep tests conducted by us. Thirdly, based on the modified HBM and KBM proposed in this study and the calibrated model parameters, the subsidence of an ocean lighthouse constructed on a reclaimed land in the South China Sea is numerically analyzed. The numerically predicted results illustrate that the creep subsidence of the ocean lighthouse in the future 50-year is 17.2 mm to 42.5 mm, meeting the mandatory requirement (<200 mm) stipulated by the China national design code. Finally, the sensitivity of the predicted creep subsidence to the model parameters is screened by performing parametric analysis.

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        Establishment and evaluation of a murine anb3-integrinexpressing cell line with increased susceptibility to Foot-and-mouth disease virus

        Wei Zhang,Kaiqi Lian,Fan Yang,Yang Yang,Zhijian Zhu,Zixiang Zhu,Weijun Cao,Ruoqing Mao,Ye Jin,Jijun He,Jianhong Guo,Xiangtao Liu,Haixue Zheng 대한수의학회 2015 Journal of Veterinary Science Vol.16 No.3

        Integrin anb3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and rolesof anb3 integrin, a stable CHO-677 cell line expressing the murine anb3 heterodimer (designated as “CHO-677-manb3” cells) wasestablished using a highly efficient lentiviral-mediated gene transfer technique. Integrin subunits an and b3 were detected at the gene andprotein levels by polymerase chain reaction (PCR) and indirect immunofluorescent assay (IFA), respectively, in the CHO-677-manb3 cellline at the 20th passage, implying that these genes were successfully introduced into the CHO-677 cells and expressed stably. A plaque-formingassay, 50% tissue culture infective dose (TCID50), real-time quantitative reverse transcription-PCR, and IFA were used to detect the replicationlevels of Foot-and-mouth disease virus (FMDV) in the CHO-677-manb3 cell line. After infection with FMDV/O/ZK/93, the cell line showeda significant increase in viral RNA and protein compared with CHO-677 cells. These findings suggest that we successfully established a stableanb3-receptor-expressing cell line with increased susceptibility to FMDV. This cell line will be very useful for further investigation of anb3integrin, and as a cell model for FMDV research.

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