http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Ibsen, Lars Bo (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
-
Ibsen Henric Ongidi,Fadhila Yusuf Abdulsalaam,Thomas Mombo Amuti,Wycliffe O,Kaisha,Kirsteen O,Awori,Anne Naipanoi Pulei 대한해부학회 2021 Anatomy & Cell Biology Vol.54 No.2
Codeine is an opioid analgesic and antitussive that has been widely abused. Some adverse effects noted with its abuse include adrenocortical insufficiency and activation of the hypothalamic-pituitary-adrenal axis. The structural basis for these dysfunctions is not clearly understood. Twenty-five adult male rats were used for the study. They were divided into intervention and control groups that were administered 40 mg/kg of codeine phosphate and normal saline respectively by gavage daily for 50 days. Subsequently, both groups were given normal saline for a further fourteen days to note recovery changes. At day 0, 50 and 64, rats were randomly selected from both groups, euthanized and adrenal glands harvested for histological processing and analysis. At day 50 of codeine administration, the adrenal glands demonstrated an increase in zona fasciculata thickness but a decrease in zona reticularis thickness. Lower values were noted in the volume density of zona reticularis and cells count of the medulla in the experimental compared to the control groups (P-value<0.05). The experimental group also showed an increase in vascularization and connective tissue in the glands. After 14 days of recovery, most of the changes observed in experimental animals were reversed and the adrenal glands in both groups had similar features. A decrease in cell count of the adrenal medulla was however observed (P-value<0.05). In conclusion administration of codeine phosphate causes discernible changes in the microscopic structure of the adrenal gland, most of which appear to be reversed after two weeks recovery period.
-
Monotonic loading of circular surface footings on clay
Lars Bo Ibsen,Amin Barari 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.12
Appropriate modeling of offshore foundations under monotonic loading is a significant challenge in geotechnical engineering. This paper reports experimental and numerical analyses, specifically investigating the response of circular surface footings during monotonic loading and elastoplastic behavior during reloading. By using the findings presented in this paper, it is possible to extend the model to simulate the vertical-load displacement response of offshore bucket foundations.
-
Transient analysis of monopile foundations partially embedded in liquefied soil
Barari, Amin,Bayat, Mehdi,Saadati, Meysam,Ibsen, Lars Bo,Vabbersgaard, Lars Andersen Techno-Press 2015 Geomechanics & engineering Vol.8 No.2
In this study, the authors present a coupled fluid-structures-seabed interaction analysis of a monopile type of wind turbine foundations in liquefiable soils. A two dimensional analysis is performed with a nonlinear stiffness degradation model incorporated in the finite difference program Fast Lagrangian Analysis of Continua (FLAC), which captured the fundamental mechanisms of the monopiles in saturated granular soil. The effects of inertia and the kinematic flow of soil are investigated separately, to highlight the importance of considering the combined effect of these phenomena on the seismic design of offshore monopiles. Different seismic loads, such as those experienced in the Kobe, Santa Cruz, Loma Prieta, Kocaeli, and Morgan Hill earthquakes, are analyzed. The pore water pressure development, relative displacements, soil skeleton deformation and monopile bending moment are obtained for different predominant frequencies and peak accelerations. The findings are verified with results in the liter.
-
Duncan Anangwe,Moses Madadi Obimbo,Ibsen Henric Ongidi,Peter Bundi Gichangi 대한해부학회 2024 Anatomy & Cell Biology Vol.57 No.1
Hypogonadism is associated with an increased risk of coronary artery disease. This study sought to describe the histomorphology of the left coronary arteries of the adult male rabbit following orchiectomy and subsequent testosterone administration. We included 20 adult male rabbits, divided into a baseline group (n=2), an interventional group subjected to castration only (n=6), an intervention group subjected to castration followed by testosterone injection (n=6), and a control group (n=6). Key variables under investigation were serum testosterone levels, the intima-media thickness of coronary arteries, smooth muscle cell density, and adventitial collagen fiber density. The mean coronary arteries’ intimal medial thickness was significantly higher in the castrated group than in controls (0.488 mm and 0.388 mm, respectively), while the testosterone-injected group had a mean of 0.440 mm. Mean smooth muscle cell density was significantly lower in the castrated rabbits vs. controls (26.96% and 47.80%, respectively), this observation being reversed with testosterone injection (47.53%). Mean adventitial collagen fiber density was significantly higher in the castrated group than in controls (66.6% and 36.1%, respectively), with a marginal difference after testosterone injection (65.2%). This study demonstrates that castration induced hypogonadism causes morphological changes in the coronary arteries that are partly reversible using testosterone injections. These findings provide a morphological basis for understanding the role of testosterone in coronary arteries.
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
