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Song, Hyejin,Kwon, Yunik,Sohn, Seok Su,Koo, Minseo,Kim, Nack J.,Lee, Byeong-Joo,Lee, Sunghak Elsevier 2018 Materials science & engineering. properties, micro Vol.730 No.-
<P><B>Abstract</B></P> <P>In this study, (austenite+ferrite+κ-carbide) triplex microstructures were obtained from the hot-rolling and subsequent 800 °C-annealing of Fe-0.8C-(12,15,20)Mn-7Al (wt%) lightweight steels, and their effects on ultra-high strength along with good ductility were investigated in relation with microstructural evolutions occurring during the tensile deformation. In the 12-wt%-Mn hot-rolled specimen, lamellar κ-carbides were populated along austenite grain boundaries, which seriously deteriorated the ductility. When the Mn content increased to 15 or 20 wt%, the volume fraction of κ-carbide decreased, and slip bands were sufficiently formed inside austenite grains during the deformation, which resulted in excellent ductility as well as ultra-high strengths. Very high yield strength was also achieved by forming triplex microstructures, in which the austenite deformed during the hot rolling greatly contributed to the strength enhancement. In the 800 °C-annealed specimens, the decreased volume fraction and morphological change from lamellar to polygonal-particle type of κ-carbides enhanced the ductility in spite of the slightly reduced strengths. This was because slip bands were sufficiently formed in austenite grains during the deformation, while voids were formed inside well-developed slip bands. The existence of a large amount of austenite was highly valuable for increasing the ductility by developing fine dislocation substructures such as Taylor lattices as a key feature of deformation mechanisms.</P>
10개월 영아에서 발병한 단일 폐병변 랑게르한스세포 조직구증의 증례
장혜진 ( Hyejin Jang ),김윤희 ( Yoon Hee Kim ),김경원 ( Kyung Won Kim ),손명현 ( Myung Hyun Sohn ),유철주 ( Chuhl Joo Lyu ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.3
Langerhans cell histiocytosis (LCH) is characterized by clonal proliferation and accumulation of abnormal dendritic (Langerhans) cells in various organs. Pulmonary involvement, although rare in children, has been reported in 20%-50% of childhood cases of multisystem LCH. Isolated pulmonary LCH in children, especially in infants, is still rarer, but should be suspected in those with cystic lung disease. We report a case of a 10-month-old boy who presented with chronic dyspnea and whose chest computed tomography (CT) scan demonstrated cystic lesions. Lung biopsy established the diagnosis of LCH; microscopy revealed a background of lymphocytes and eosinophils with kidney-shaped abnormal cells. These abnormal cells were positive for S-100, CD207 (Langerin), and CD1a on immunohistochemical staining. Chemotherapy was administered using a cytotoxic agent (vinblastine) and a steroid. After 12 weeks of induction chemotherapy, although no significant change in cyst size was noted on chest CT, clinical symptoms improved. Consolidation chemotherapy was then administered for 1 year. Thereafter, chest CT findings demonstrated a significant decrease in cyst size and a significant increase in the volume of normal lung parenchyma. Therefore, aggressive treatment of isolated pulmonary LCH in infants with severe tissue destruction and symptoms seems warranted. (Allergy Asthma Respir Dis 2018;6:179-183)
Novel ultra-high-strength Cu-containing medium-Mn duplex lightweight steels
Song, Hyejin,Yoo, Jisung,Kim, Sang-Heon,Sohn, Seok Su,Koo, Minseo,Kim, Nack J.,Lee, Sunghak Elsevier 2017 Acta materialia Vol.135 No.-
<P>High strength and ductility and vehicle's weight reduction are key issues for improving fuel efficiency in automotive industries. In addition, structural reinforcement components require high yield strength because the prevention or minimization of deformation is more important than the absorption of impact energy. In this study, new ultra-high-strength duplex lightweight Fe-0.5C-12Mn-7Al-(0,3)Cu (wt%) steels have been developed by varying annealing temperature. Here, Cu, an austenite stabilizer, not only raises the austenite volume fraction but also delays the recrystallization due to a solute drag effect, while it promotes the formation of Cu-rich B2 particles and Cu-segregated interfacial layers. The steels show the planar slip and fine dislocation substructures (Taylor lattices) as desirable deformation mechanisms. Non-shearable Cu-rich B2 particles, solid solution hardening of Cu, and delayed recrystallization greatly improve the yield strength (similar to 1 GPa) and strain hardening. Through these unique and excellent tensile properties together with weight saving of 10.4%, the present work provides a desirable possibility for applications to automotive reinforcement components preferentially requiring an excellent yield-to-tensile ratio. (C) 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.</P>
뼈 전이를 동반한 진행성 위암 환자에서의 Flare Phenomenon
이상기 ( Sangki Lee ),시혜진 ( Hyejin Shi ),손성민 ( Sungmin Sohn ),박성락 ( Sungrock Park ),왕성호 ( Sungho Wang ),송진경 ( Jinkyung Song ),장근두 ( Geundoo Jang ) 대한내과학회 2016 대한내과학회지 Vol.91 No.3
Flare phenomenon refers to increased radiotracer uptake in bones despite clinical findings showing a positive response to treatment. Flare phenomena are most often observed in patients with breast or prostate cancer. Here, we present a case of bone flare in a 54-year-old male who had advanced gastric cancer with bone metastases. After three cycles of chemotherapy, a bone scan showed increased intensity, but the patient`s bone pain was alleviated and abdominal computed tomography revealed a decrease in the size of the primary mass and metastatic lymph nodes. We therefore continued chemotherapy using the same regimen, and a follow- up bone scan revealed decreased intensity. A flare phenomenon after treatment is rare in cases of gastric cancer with bone metastasis. Although flare phenomena are not common, they should be considered in patients with gastric cancer when the clinical results are inconsistent with bone-scan findings. (Korean J Med 2016;91:321-324)