http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
허은주 昌原大學校 基礎科學硏究所 1998 基礎科學硏究所論文集 Vol.10 No.-
Interest in seeking biologically active compounds has prompted increased studies in isochroman derivatives. these bicyclic derivatives can be used interchangeably iological activity we are synthesizing isochroman through α-haloboronic ester snthetic approach
비소세포 폐암 환자의 2차 치료로서 Gemcitabine과 Vinorelbine의 병합 요법의 효과
이은주 ( Eun Joo Lee ),하은실 ( Eun Sil Ha ),박상훈 ( Sang Hoon Park ),허규영 ( Gyu Young Hur ),정기환 ( Ki Hwan Jung ),정혜철 ( Hye Cheol Jeong ),이승룡 ( Sung Yong Lee ),김제형 ( Je Hyeong Kim ),이상엽 ( Sang Yeub Lee ),신철 ( 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.59 No.5
항암화학요법을 받는 소아암 환아 가족의 간호 요구도와 간호 만족도
박은정(Park, Eun Jung),정정희(Jeong, Jeong Hee),진성례(Jin, Seong Rye),조은주(Cho, Eun Joo),김주연(Kim, Ju Youn),신지현(Shin, Ji Hyun),허명은(Hur, Myung Eun),서민정(Seo, Min Jung),차은경(Cha, Eun Kyung),노기옥(Noh, Gie Ok) 대한종양간호학회 2017 Asian Oncology Nursing Vol.17 No.2
Purpose: The aim of this study was to explore the nursing needs and satisfaction of pediatric cancer patient families during chemotherapy. Methods: Data collection was conducted from April to July 2016 using the questionnaire of nursing needs and satisfaction developed by the researchers in 123 families of children who were diagnosed with pediatric cancer and undergoing chemotherapy. The collected data were analyzed by descriptive statistics, t-test, and ANCOVA using the SPSS 22.0 program. Results: Nursing needs and satisfaction were 4.27 ± 0.78 and 4.16 ± 0.57, respectively. Significant differences between nursing need and satisfaction were observed in the educational/informational domain (t=3.94, p=<.001) and community resources nursing domain (t=2.16, p=.032). Also, in terms of general characteristics, the nursing needs were significantly different depending on the elapsed time after diagnosis (t=1.98, p=.049), and the nursing satisfaction was significantly different depending on the type of treatment (F=4.02, p=.009). Conclusion: Based on the results of this study, when caring for children who are receiving chemotherapy and their family, it is necessary to develop nursing interventions that meet the individualized nursing needs of those directly and indirectly affected.
Eun Joo Chung,Hwa Jin Cho,Wooyoung Jang,Dae Young Hur,Yeong Seok Kim,Kyung-Hwa Lee,Sang Jin Kim 대한의학회 2022 Journal of Korean medical science Vol.37 No.22
Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) overlap clinically with parkinsonism or extrapyramidal signs and pathologically with tauopathy. Asymmetric parkinsonism and cortical dysfunctions are classical features of CBD. However, symmetric parkinsonism, frequent falls, and supranuclear gaze palsy are key features of PSP. Despite biochemically classified as 4R tauopathies, tufted astrocytes of PSP and astrocytic plaque of CBD show pathologically important differences. Herein, we report a 68-year-old man with pathologically confirmed CBD. He was clinically suspected to have PSP because of progressive gait disturbances, frequent falls, and vertical saccade limitation. Neurological examination performed at age 71 revealed symmetrical bradykinesia, axial rigidity, and postural instability with worsening of early existing symptoms. Magnetic resonance imaging of the brain taken at age 70 detected midbrain and left frontotemporal atrophy and right middle cerebral artery infarction. Left frontotemporoparietal hypometabolism and asymmetrically decreased fluoro-propyl-carbomethoxy-iodophenyl-tropane uptake in the basal ganglia were observed. The autopsy was performed at the time of his death (at age 72), which revealed severe pallor of the substantia nigra and mildly hypopigmented locus ceruleus. AT8 immunohistochemistry and Gallyas staining revealed tau-positive neuronal and glial inclusions, astrocytic plaques, ballooned neurons, and numerous threads in both gray and white matter. No abnormal inclusions were revealed by beta-amyloid, α-synuclein and TDP43 immunohistochemistry. In our case, cerebral infarction, periventricular and deep white matter ischemic changes, and midbrain atrophy were likely to produce PSP–CBD overlapping symptoms. However, our patient was finally confirmed to have CBD based on pathological findings such as astrocytic plaques.
Clinical Characteristics of Smoking Asthmatics
( Eun Sil Ha ),( Hye Ok Kim ),( Kyoung Ju Lee ),( Eun Joo Lee ),( Gyu Young Hur ),( Ki Hwan Jung ),( Sung Yong Lee ),( Je Hyeong Kim ),( Sang Yeub Lee ),( Chol Shin ),( Jae Jeong Shim ),( Kyung Ho Kan 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.6
Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history-current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second (FEV1) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean FEV1 (% predicted) was 76.8±19.8%, 71.6±21.1% and 87.9±18.7% for current smokers, former smokers and non-smokers, respectively (p<0.001). The FEV1/forced vital capacity (FVC) (ratio, %) values were 63.6±12.6%, 59.3±14.9% and 72.1±11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual FEV1 slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients.
Hur, Bo Yun,Lee, Jeong Min,Lee, Jeong Eun,Park, Jae Yong,Kim, Soo Jin,Joo, Ijin,Shin, Cheong Il,Baek, Jee Hyun,Kim, Jung Hoon,Han, Joon Koo,Choi, Byung Ihn Wiley Subscription Services, Inc., A Wiley Company 2012 JOURNAL OF MAGNETIC RESONANCE IMAGING Vol.36 No.1
<P><B>Abstract</B></P><P><B>Purpose:</B></P><P>To determine the characteristic magnetic resonance imaging (MRI) features of mass‐forming autoimmune pancreatitis (AIP), which allow its differentiation from pancreatic adenocarcinoma (PAC).</P><P><B>Materials and Methods:</B></P><P>MR images of 37 patients with either pathologically proven, mass‐forming AIPs (<I>n</I> = 9) or PACs (<I>n</I> = 28) were retrospectively reviewed. The pancreatic MR protocol included unenhanced images, contrast‐enhanced dynamic images, diffusion‐weighted imaging (DWI), and MR‐cholangiopancreatography (MRCP). Two reviewers analyzed the MR images regarding the number, location, morphologic features, and enhancement degree and pattern of the lesions as well as secondary changes of the pancreatic parenchyma, the biliary and pancreatic ducts. The size and apparent diffusion coefficient (ADC) values of the lesions were measured.</P><P><B>Results:</B></P><P>Although sensitivities were low (28.6%–44.4%), specificities of multiplicity, capsule‐like rim enhancement, and skipped stricture of the biliary or pancreatic duct in mass‐forming AIP were high (100%). Sensitivities and specificities of irregular or geographic shape, delayed enhancement, and a low ADC value <1.26 × 10<SUP>−3</SUP> mm<SUP>2</SUP>/s in mass‐forming AIP were favorable (71.4%–83.3% and 78.5%–89.3%).</P><P><B>Conclusion:</B></P><P>Although to differentiate mass‐forming AIP from pancreatic cancer is difficult, the combination of MRI findings including contrast‐enhanced dynamic images, MRCP, and DWI can be a help. J. Magn. Reson. Imaging 2012;36:188–197. © 2012 Wiley Periodicals, Inc.</P>
Eun Joo Chung,Hwa Jin Cho,Dae Young Hur,Yeong Seok Kim,Kyung-Hwa Lee,Sang Jin Kim 대한의학회 2022 Journal of Korean medical science Vol.37 No.23
Lewy bodies (LBs) and Lewy neurites (LNs) are pathological hallmarks of Parkinson’s disease (PD) or dementia with LBs (DLB). Incidental Lewy body disease (iLBD) is defined when LBs and LNs are found in the brain of normal elderly individuals. A 65-year-old man presented with autopsy-proven Lewy body pathology (LBP). He had never complained of cognitive impairments or parkinsonian motor symptoms, and he had always maintained independence in activities of daily living. Hypopigmentations in the locus coeruleus and substantia nigra were discovered during the autopsy. The patient showed severe-to-extremely severe LBs in the neocortex and limbic areas, except in the nucleus basalis of Meynert, amygdala, and brainstem, according to microscopic findings. Hence, using several of the previously known staging systems, it was difficult to classify the patient’s LBP type. Furthermore, these findings were unique because they had never been observed before in iLBD.