High-Frequency Dimmable Electronic Ballast for Automotive HID Lamps

Huang-Jen Chiu1,Hsiu-Ming Huang,Li-Wei Lin,Shann-Chyi Mou,Pang-Jung Liu 제어로봇시스템학회 2005 제어로봇시스템학회 국제학술대회 논문집 Vol.2005 No.6

A High Efficiency Power Supply with High Power Factor Input

Huang-Jen Chiu,Hsiu-Ming Huang,Li-Wei Lin,Shann-Chyi Mou,Pang-Jung Liu 제어로봇시스템학회 2005 제어로봇시스템학회 국제학술대회 논문집 Vol.2005 No.6

Health Care Utilization and Expenditures of Patients with Diabetes Comorbid with Depression Disorder: A National Population-Based Cohort Study

Chun-Jen Huang,Hui-Min Hsieh,Herng-Chia Chiu,Peng-Wei Wang,Mei-Hsuan Lee,Chih-Yi Li,Ching-Hua Lin 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.6

Objective: The study investigated to compare health care utilization and expenditures between diabetic patients with and without depression in Taiwan. Methods: Health care utilization and expenditure among diabetic patients with and without depression disorder during 2000 and 2004 were examined using Taiwan’s population-based National Health Insurance claims database. Health care utilization included outpatient visits and the use of inpatient services, and health expenditures were outpatient, inpatient, and total medical expenditures. Moreover, general estimation equation models were used for analyzing the factors associated with outpatient visits and expenditures. Multiple logistic regression analysis was applied for identifying the factors associated with hospitalization. Results: The average annual outpatient visits and annual total medical expenditures in the study period were 44.23–52.20; NT$87,496–133,077 and 30.75–32.92; NT$64,411–80,955 for diabetic patients with and without depression. After adjustment for covariates, our results revealed that gender and complication were associated with out-patient visits. Moreover, the time factor was associated with the total medical expenditure, and residential urbanization and complication factors were associated with hospitalization. Conclusion: Health care utilization and expenditures for diabetic patients with depression were significantly higher than those without depression. Sex, complications, time, and urbanization are the factors associated with health care utilization and expenditures.

Analgesic and Anti-Inflammatory Activities of Rosa taiwanensis Nakai in Mice

Der-Shiang Tsai,Mei-Hsuen Huang,Jen-Chieh Tsai,Yuan-Shuang Chang,Yung-Jia Chiu,Yen-Chang Lin,Lung-Yuan Wu,Wen-Huang Peng 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.5

In this study, we evaluated the analgesic and anti-inflammatory activities of a 70% ethanol extract from Rosa taiwanensis Nakai (RTEtOH). The analgesic effect was determined using acetic acid-induced writhing response and formalin test. The anti-inflammatory activity was evaluated by λ-carrageenan-induced paw edema in mice. The anti-inflammatory mechanism of RTEtOH was examined by measuring the levels of cyclooxygenase-2 (COX-2), nitric oxide (NO), tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and malondialdehyde (MDA) in the paw edema tissue and the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GRd) in the liver tissue. The betulinic acid and oleanolic acid contents of RTEtOH were assayed by HPLC. The results showed that RTEtOH decreased the acetic acid-induced writhing responses (1.0 g/kg) and the late phase of the formalin-induced licking time (0.5 and 1.0 g/kg). In the anti-inflammatory models, RTEtOH (0.5 and 1.0 g/kg) reduced the paw edema at 3, 4, and 5 h after λ-carrageenan administration. Moreover, the anti-inflammatory mechanisms might be due to the decreased levels of COX-2, TNF-α, IL-1β, and IL-6, as well as the inhibition of NO and MDA levels through increasing the activities of SOD, GPx, and GRd. The contents of two active compounds, betulinic acid and oleanolic acid, were quantitatively determined. This study demonstrated the analgesic and anti-inflammatory activities of RTEtOH and provided evidence to support its therapeutic use in inflammatory diseases.

Design of Three Phase Wye-Delta LLC Converter with Time Domain Analysis

Kuan-Hung Chen,Jing-Yuan Lin,Yi-Feng Lin,Yu-Chen Chang,Huang-Jen Chiu 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

In the paper, the performance of a 5 kW DC/DC Wye-Delta-based series resonant converter designed for 400V input voltage and 48V output voltage server power supply is evaluated. The paper also performs operation modes analysis, circuit characteristics analysis, and use time domain analysis on Wye-Delta-based series resonant converter for circuit design to replace FHA analysis due to waveform distortion. Finally, a full-load efficiency up to 96.07% and power-density up to 2.84W/cm3 server power supply is implemented.

Antioxidative and Hepatoprotective Effects of Magnolol on Acetaminophen-induced Liver Damage in Rats

Yung-Hsiang Chen,Feng-Yen Lin,Po-Len Liu,Yi-Tsau Huang,Jen-Hwey Chiu,Yi-Chun Chang,Kee-Ming Man,Chuang-Ye Hong,Yen-Yi Ho,Ming-Tsung Lai 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.2

Acute liver failure (ALF), an often fatal condition characterized by massive hepatocyte necrosis, is frequently caused by drug poisoning, particularly with acetaminophen (N-acetyl-p-aminophenol/APAP). Hepatocyte necrosis is consecutive to glutathione (GSH) depletion and mitochondrial damage caused by reactive oxygen species (ROS) overproduction. Magnolol, one major phenolic constituent of Magnolia officinalis, have been known to exhibit potent antioxidative activity. In this study, the anti-hepatotoxic activity of magnolol on APAP-induced toxicity in the Sprague-Dawley rat liver was examined. After evaluating the changes of several biochemical parameters in serum, the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) were elevated by APAP (500 mg/kg) intraperitoneal administration (8 and 24 h) and reduced by treatment with magnolol (0.5 h after APAP administration; 0.01, 0.1, and 1 μg/kg). Histological changes around the hepatic central vein, lipid peroxidation (thiobarbituric acid-reactive substance/TBARS), and GSH depletion in liver tissue induced by APAP were also recovered by magnolol treatment. The data show that oxidative stress followed by lipid peroxidation may play a very important role in the pathogenesis of APAP-induced hepatic injury; treatment with lipid-soluble antioxidant, magnolol, exerts anti-hepatotoxic activity. Our study points out the potential interest of magnolol in the treatment of toxic ALF.

High Power Density Asymmetrical Full-Bridge Soft-Switching Inverter

Pei-Chin Chi,Cheng-Yen Chou,Marojahan Tampubolon,Yao-Ching Hsieh,Jing-Yuan Lin,Huang-Jen Chiu 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

This paper presents a Zero-Voltage-Switching (ZVS) technique eliminating the switching loss on a proposed single phase bi-directional full-bridge Buck inverter in which asymmetrical filter topology and control scheme are for each arm. Here Metal-Oxide-Field-Effect- Transistor(MOSFET) is chosen as the switching device, an L₁-C₁ filter is connected across the full-bridge, an L₂ filter is connected in series to load or grid. While the arm connecting with the C₁ is controlled by the polarity of 50Hz sinusoid reference command and the arm connecting with the L₁ is controlled by a Pulse-Width-Modulation(PWM) signal modulated by sinusoid, the L₁-C₁ then operates as an output filter of Buck, and the succeeding L₂ filter further attenuates ripple current flowing to load or grid. The ZVS technique sets the L₁ inductance such low that its current flows bi-directionally within a switching period, then the bidirectional current with sufficiently high peaks in turn charge and discharge the output capacitance Coss of MOSFETs of the switching arm within floating time, defined as the duration when both MOSFETs of an arm are off, to let the MOSFETs D-S channels be turned on or off at the state that Coss are fully discharged to zero voltage, so ZVS of MOSFET is achieved. Under the ZVS operation without frequency proportional switching loss, the switching frequency is possible to be raised to high to compact the sizes of passive components and heat sink of the inverter for achieving high power density. Simulation and experiment have been carried out to verify the ZVS operation.

A DSP-Based Differential Boost Inverter with Maximum Power Point Tracking

Marojahan Tampubolon,Irwan Purnama,Pei-Chin Chi,Jing-Yuan Lin,Yao-Ching Hsieh,Huang-Jen Chiu 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

This paper presents a DSP-based differential boost inverter (DBI) with maximum power point tracking (MPPT) for photovoltaic (PV) applications. In a conventional DC/AC MPPT system, power of photovoltaic is delivered into two stages, they are DC/DC boost converter and buck type DC/AC inverter. A DC link capacitor appears between these two stages. Furthermore the system has higher complexity and costly than that of DC/AC MPPT system with a single stage boost inverter. Here, a single stage differential boost inverter is implemented. Since it can produce a sinusoidal output voltage higher than its DC voltage input, it is not only able to reduce the stage number of DC/AC MPPT system but also able to eliminate the DC link capacitor. The MPPT method employed in this study is P&O method. This technique is widely used due to its easy implementation, and unimportant extreme weather change consideration. To implement this technique, a digital signal processor (DSP) was used. In this paper, a review of DBI and MPPT implementation are presented. Finally a 400W laboratory prototype has been built. The result shows that the P&O MPPT method has been successfully implemented for various PV power and it can reach 95% maximum MPPT accuracy. In addition, the DBI is able to produce a sinusoidal output voltage at the various PV power conditions.