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      • Space Deformation of Parametric Surface Based on Extension Function

        Wang, Xiaoping,Ye, Zhenglin,Meng, Yaqin,Li, Hongda Society for Computational Design and Engineering 2002 International Journal of CAD/CAM Vol.1 No.1

        In this paper, a new technique of space deformation for parametric surfaces with so-called extension function (EF) is presented. Firstly, a special extension function is introduced. Then an operator matrix is constructed on the basis of EF. Finally the deformation of a surface is achieved through multiplying the equation of the surface by an operator matrix or adding the multiplication of some vector and the operator matrix to the equation. Interactively modifying control parameters, ideal deformation effect can be got. The implementation shows that the method is simple, intuitive and easy to control. It can be used in such fields as geometric modeling and computer animation.

      • KCI등재

        Proliferated Leydig Cells for Engineered Testis-like Tissue Regeneration with Testosterone-Secreting Ability

        Hongda Bi,Xiaoyun Wang,Wei Liu,Yilin Cao,Guangdong Zhou,Xin Xing 한국조직공학과 재생의학회 2014 조직공학과 재생의학 Vol.11 No.5

        Tissue engineering approach provides a hopeful strategy for reconstructing testis testosterone-secreting functions. However, limited source and low proliferative activity in vitro of Leydig cells (LCs, the main testosteroneproducing cells) makes testis-like tissue regeneration difficult to be achieved. This study explored the feasibility of in vitro expanding LCs and their potential application in testis-like tissue regeneration. LC lineage cells were isolated from Sprague-Dawley (SD) rats by differential adhesion method and cell composition was identified by expressions of 3β-HSD, LHR, LIFR, and c-kit. A modified expansion medium (EM) system was used to test the feasibility of in vitro expanding LC lineage. The results showed that the attached cells reached a high purification of LC lineage (>90%, indicated by positive expression of 3β-HSD) and that EM significantly enhanced proliferation of LC lineage compared to regular medium, which was testified to be related to the presence of stem LCs that was implied by positive expressions of LIFR and c-kit as well as the transition of 3β-HSD expression from negative to positive in partial cells. Importantly, the proliferated LCs showed relatively sustained testosterone-secreting ability in vitro and these cells combined with biodegradable scaffolds successfully regenerated testis-like tissue with sustained testosteronesecreting function in vivo, which was supported by the enhanced serum testosterone level in castrated rats. All these results indicated that the differential adhesion method could efficiently isolate and purify LC lineage and that EM system could efficiently promote proliferation and functional maintenance of LC lineage, providing a good cell source for testes-like tissue regeneration. Tissue engineering approach provides a hopeful strategy for reconstructing testis testosterone-secreting functions. However, limited source and low proliferative activity in vitro of Leydig cells (LCs, the main testosteroneproducing cells) makes testis-like tissue regeneration difficult to be achieved. This study explored the feasibility of in vitro expanding LCs and their potential application in testis-like tissue regeneration. LC lineage cells were isolated from Sprague-Dawley (SD) rats by differential adhesion method and cell composition was identified by expressions of 3β-HSD, LHR, LIFR, and c-kit. A modified expansion medium (EM) system was used to test the feasibility of in vitro expanding LC lineage. The results showed that the attached cells reached a high purification of LC lineage (>90%, indicated by positive expression of 3β-HSD) and that EM significantly enhanced proliferation of LC lineage compared to regular medium, which was testified to be related to the presence of stem LCs that was implied by positive expressions of LIFR and c-kit as well as the transition of 3β-HSD expression from negative to positive in partial cells. Importantly, the proliferated LCs showed relatively sustained testosterone-secreting ability in vitro and thesecells combined with biodegradable scaffolds successfully regenerated testis-like tissue with sustained testosteronesecreting function in vivo, which was supported by the enhanced serum testosterone level in castrated rats. All these results indicated that the differential adhesion method could efficiently isolate and purify LC lineage and that EM system could efficiently promote proliferation and functional maintenance of LC lineage, providing a good cell source for testes-like tissue regeneration.

      • An On-line Strategy based on Rolling State Prediction for Hybrid Energy Storage System of Tram

        Yu Wang,Zhongping Yang,Fei Lin,Xiaochun Fang,Xingkun An,Hongda Zhou 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        This paper aims at a hybrid tram with the onboard battery-supercapacitor storage system. This paper proposes an on-line strategy based on rolling state prediction (ROS). A wavelet neural network (WNN) is used to predict the running state of the tram in a certain period of time in the future according to the historic data, and the dynamic programming (DP) algorithm is used to optimize the energy management strategy (EMS) during the period. The strategy aims to optimize the system efficiency and battery life. Compared with classical rule-based (RB) strategy, ROS greatly increases the system efficiency and lengthens lifespan of battery and achieves real-time optimization.

      • KCI등재

        The impact of organizational innovation climate on employee innovation behavior in emissions control enterprises: an empirical study in China

        김동주,Wang Shuyang,Jia Hongda 부산대학교 중국연구소 2023 Journal of China Studies Vol.26 No.3

        To mitigate climate change, emissions control enterprises need to innovate to strike a balance between corporate economics and the environment. Businesses are the mainstay of innovation in the marketplace, but innovation has its roots in employees, and the ability of employees to effectively implement individual innovative behavioral activities within the organization is an essential factor affecting a business's ability to innovate. Then how to promote employee's innovative behavior in emissions control enterprises? Research has shown that a positive climate for organizational innovation stimulates employee creativity, encouraging them to introduce fresh ideas and solutions to problems. Organizational commitment can increase employees' sense of belonging and identity and motivate them to contribute to the organization's growth. Psychological empowerment can increase employee autonomy and decision-making power, demonstrate creativity and initiative, and make them more willing to introduce fresh ideas and try different approaches. To promote the low-carbon development of China's emissions control enterprises and improve the innovation behavior of their employees. The study intends to provide practical policies and practical recommendations for improving employee innovation behavior, while providing some references for related industries. To this end, a total of 607 effective questionnaires were collected from emissions controls enterprises' employees in China. SPSS 26.0 and AMOS 24.0 were used for confirmation reliability analysis, exploratory factor analysis, confirmation factor analysis, path analysis and mediation effect analysis. The results show the organizational innovation climate of Chinese emission control enterprises has a positive (+) effect on employee innovation behavior; organizational commitment and psychological empowerment have a positive (+) effect on employee innovation behavior. In an organizational innovation climate, organizational commitment and psychological empowerment have a moderating effect on employee innovative behavior.

      • KCI등재

        Simulation Analysis of Electromagnetic Characteristics of Electric Vehicle Cable Under Tensile Condition

        Ma Ping,Deng Tengfei,Ye Yongsheng,Wang Xinghua,Zhao Hongda 한국전기전자재료학회 2022 Transactions on Electrical and Electronic Material Vol.23 No.4

        This paper mainly studies the stress and strain characteristics of electric vehicle cables under tensile state and its influence law on the electromagnetic characteristics. Firstly, the structure and characteristics of new energy vehicle cables are analyzed, and the three-dimensional solid model of the cables is established. The finite element method is used to analyze the deformation law and stress change characteristics of cables under diff erent tensile load conditions, so as to achieve the resistance change law of cables. Then the equivalent modeling method is established to simulate the electromagnetic characteristics of the cable. It is found that the tensile deformation increases the electromagnetic field intensity of some parts of the cable, leading to the irregular distribution of electromagnetic field in the entire cable. Finally, the variation law of electromagnetic field during the cable deformation is summarized.

      • Computational Screening of Nanoporous Materials for Hexane and Heptane Isomer Separation

        Chung, Yongchul G.,Bai, Peng,Haranczyk, Maciej,Leperi, Karson T.,Li, Peng,Zhang, Hongda,Wang, Timothy C.,Duerinck, Tim,You, Fengqi,Hupp, Joseph T.,Farha, Omar K.,Siepmann, J. Ilja,Snurr, Randall Q. American Chemical Society 2017 Chemistry of materials Vol.29 No.15

        <P>Computational high-throughput screening was carried out to assess a large number of-experimentally reported metal-organic frameworks (MOFs) and zeolites for their utility in hexane isomer separation. Through the work, we identified many MOFs and zeolites with high selectivity (SL+M > 10) for the group of n-hexane, 2-methylpentane, and 3-methylpentane (linear and monobranched isomers) versus 2,2-dimethylbutane and 2,3-dimethylbutane (dibranched isomers). This group of selective sorbents includes VICDOC (Fe-2(BDP)(3)), a MOF with triangular pores that is known to exhibit high isomer selectivity and capacity. For three of these structures, the adsorption isotherms for a 10-component mixture of hexane and heptane isomers were calculated. Subsequent simulations of column breakthrough curves showed that the DEYVUA MOF exhibits a longer process cycle time than VICDOC MOF or MRE zeolite, which are previously reported, high-performing materials, illustrating the importance of capacity in designing MOFs for practical applications. Among the identified candidates, we synthesized and characterized a MOF in a new copper form with high predicted adsorbent capacity (q(L+M) > 1.2 mol/L) and moderately high selectivity (SL+M approximate to 10). Finally, we examined the role of pore shape in hexane isomer separations, especially of triangular-shaped pores. We show through the potential energy surface and three-dimensional siting analyses that linear alkanes do not populate the corners of narrow triangular channels and that structures with nontriangular pores can efficiently separate hexane isomers. Detailed thermodynamic analysis illustrates how differences in the free energy of adsorption contribute to shape selective separation in nanoporous materials.</P>

      • KCI등재

        Atomic Force Microscopy of Asymmetric Membranes from Turtle Erythrocytes

        Tian, Yongmei,Cai, Mingjun,Xu, Haijiao,Ding, Bohua,Hao, Xian,Jiang, Junguang,Sun, Yingchun,Wang, Hongda Korean Society for Molecular and Cellular Biology 2014 Molecules and cells Vol.37 No.8

        The cell membrane provides critical cellular functions that rely on its elaborate structure and organization. The structure of turtle membranes is an important part of an ongoing study of erythrocyte membranes. Using a combination of atomic force microscopy and single-molecule force spectroscopy, we characterized the turtle erythrocyte membrane structure with molecular resolution in a quasi-native state. High-resolution images both leaflets of turtle erythrocyte membranes revealed a smooth outer membrane leaflet and a protein covered inner membrane leaflet. This asymmetry was verified by single-molecule force spectroscopy, which detects numerous exposed amino groups of membrane proteins in the inner membrane leaflet but much fewer in the outer leaflet. The asymmetric membrane structure of turtle erythrocytes is consistent with the semi-mosaic model of human, chicken and fish erythrocyte membrane structure, making the semi-mosaic model more widely applicable. From the perspective of biological evolution, this result may support the universality of the semi-mosaic model.

      • KCI등재

        Atomic Force Microscopy of Asymmetric Membranes from Turtle Erythrocytes

        Yongmei Tian,Mingjun Cai,Haijiao Xu,Bohua Ding,Xian Hao,Junguang Jiang,Yingchun Sun,Hongda Wang 한국분자세포생물학회 2014 Molecules and cells Vol.37 No.8

        The cell membrane provides critical cellular functions that rely on its elaborate structure and organization. The structure of turtle membranes is an important part of an ongoing study of erythrocyte membranes. Using a combination of atomic force microscopy and single-molecule force spectroscopy, we characterized the turtle erythrocyte membrane structure with molecular resolution in a quasi-native state. High-resolution images both leaflets of turtle erythrocyte membranes revealed a smooth outer membrane leaflet and a protein covered inner membrane leaflet. This asymmetry was verified by single-molecule force spectroscopy, which detects numerous exposed amino groups of membrane proteins in the inner membrane leaflet but much fewer in the outer leaflet. The asymmetric membrane structure of turtle erythrocytes is consistent with the semi-mosaic model of human, chicken and fish erythrocyte membrane structure, making the semi-mosaic model more widely applicable. From the perspective of biological evolution, this result may support the universality of the semi-mosaic model.

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