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      • Plane harmonic waves in fractional orthotropic magneto-thermoelastic solid with rotation and two-temperature

        Himanshi,Parveen Lata Techno-Press 2023 Coupled systems mechanics Vol.12 No.2

        The present research is focused on the study of plane harmonic waves in a two-dimensional orthotropic magneto-thermoelastic media with fractional order theory of generalized thermoelasticity in the light of two-temperature and rotation due to time harmonic sources. Here, we studied three types of waves namely quasi-longitudinal (QL), quasi-transverse (QTS) and quasi thermal (QT) waves. The variations in the wave properties such as phase velocity, attenuation coefficient and specific loss have been noticed with respect to frequency for the reflected waves. Further the value of amplitude ratios, energy ratios and penetration depth are computed numerically with respect to angle of incidence. The numerical simulated results are presented graphically to show the effect of fractional parameter based on its conductivity (0<α<1 for weak, α=1 for normal, 1<α≤2 for strong conductivity) on all the components.

      • KCI우수등재

        Redox Modulatory Anti-Inflammatory Potential of Hempseed (Cannabis sativa) based Green Selenium Nanoparticles

        Himanshi Mehta,Megha Gupta,Parminder Kaur,Jaspreet Kaur,Naveen Kaushal 한국진공학회(ASCT) 2021 Applied Science and Convergence Technology Vol.30 No.3

        Biomolecules mediated synthesis of nanoparticles (NPs) has revolutionized the nanotechnology research field due to its eco-friendly and non-toxic nature. The green approaches of NPs synthesis using plant extracts offer an effective and better alternative than other synthesis methods. Metal-based NPs have emerged at the forefront of biomedicine due to their versatility in health and therapeutics. In this context, Selenium (Se), a versatile trace element is known for its critical role in various pathophysiological processes through regulation of cellular redox status and inflammatory pathways besides others. However, these beneficial effects of Se are limited by its narrow physiologically relevant concentration range. Deficiency or excess of Se is associated with numerous pathologies and toxicities. Thus, in current study we have synthesized and characterized Hempseed (Cannabis sativa) based novel biogenic Se nanoparticles (SeNPs) using UV visible spectroscopy, DLS, EDX, FE-SEM, and FT-IR. Further, the phytochemical profiles and antioxidant as well as anti-inflammatory potential of these SeNPs were evaluated to ascertain their physiological benefits. Results indicated the spherical shaped SeNPs of average size 140–150 nm with favourable zeta potential of −45.0 mV. The phytochemical and Se analysis validated the redox modulatory anti-inflammatory potential of these hempseed based green SeNPs.

      • Time harmonic interactions due to inclined load in an orthotropic thermoelastic rotating media with fractional order heat transfer and two-temperature

        Lata, Parveen,Himanshi, Himanshi Techno-Press 2022 Coupled systems mechanics Vol.11 No.4

        The objective of this paper is to study the effect of frequency in a two-dimensional orthotropic thermoelastic rotating solid with fractional order heat transfer in generalized thermoelasticity with two-temperature due to inclined load. As an application the bounding surface is subjected to uniformly and linearly distributed loads (mechanical and thermal source). The problem is solved with the help of Fourier transform. Assuming the disturbances to be harmonically time dependent, the expressions for displacement components, stress components, conductive temperature and temperature change are derived in frequency domain. Numerical inversion technique has been used to determine the results in physical domain. The results are depicted graphically to show the effect of frequency on various components. Some particular cases are also discussed in the present research.

      • Orthotropic magneto-thermoelastic solid with multi-dual-phase-lag model and hall current

        Lata, Parveen,Himanshi, Himanshi Techno-Press 2021 Coupled systems mechanics Vol.10 No.2

        The present research deals with the investigation of the effect of hall current in an orthotropic magneto-thermoelastic medium with two temperature in the context of multi-phase-lag heat transfer due to thermomechanical sources. The bounding surface is subjected to linearly distributed and concentrated loads(mechanical and thermal source).Laplace and Fourier transform techniques are used to solve the problem. The expressions for displacement components,stress components and conductive temperature are derived in transformed domain and furtherin physical domain with the help of numerical inversion techniques. The effect ofrotation and hall parameter hasshown with the help of graphs.

      • Effect of two-temperature in an orthotropic thermoelastic media with fractional order heat transfer

        Lata, Parveen,Himanshi, Himanshi Techno-Press 2021 Composite materials and engineering Vol.3 No.3

        In this article, we studied the effect of two-temperature in a two-dimensional orthotropic thermoelastic media with fractional order heat transfer in generalized thermoelasticity with three-phase-lags due to thermomechanical sources. The boundary of the surface is subjected to linearly distributed and concentrated loads (mechanical and thermal source). The solution of the problem is obtained with the help of Laplace and Fourier transform techniques. The expressions for displacement components, stress components and conductive temperature are derived in transformed domain. Numerical inversion technique is used to obtain the results in physical domain. The effect of two-temperature on all the physical quantities has been depicted with the help graphs. Some special cases are also discussed in the present investigation.

      • Rotational and fractional effect on Rayleigh waves in an orthotropic magneto-thermoelastic media with hall current

        Parveen Lata,Himanshi 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.6

        The present research is concerned to study the effect of fractional parameter and rotation on the propagation of Rayleigh waves in an orthotropic magneto-thermoelastic media with three-phase-lags in the context of fractional order theory of generalized thermoelasticity with combined effect of rotation and hall current. The secular equations of Rayleigh waves are derived by using the appropriate boundary conditions. The wave properties such as phase velocity, attenuation coefficient are computed numerically and the numerical simulated results are presented through graphs to show the effect on all the components. Some special cases are also discussed in the present investigation.

      • Fractional effect in an orthotropic magneto-thermoelastic rotating solid of type GN-II due to normal force

        Parveen Lata,Himanshi 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.81 No.4

        In this article, we have examined the effect of fractional order parameter in a two-dimensional orthotropic magnetothermoelastic solid in generalized thermoelasticity without energy dissipation with fractional order heat transfer in the context of hall current, rotation and two-temperature due to normal force. Laplace and Fourier transform techniques are used to obtain the solution of the problem. The expressions for displacement components, stress components, current density components and conductive temperature are obtained in transformed domain and then in physical domain by using numerical inversion method. The effect of fractional parameter on all the components has been depicted through graphs. Some special cases are also discussed in the present investigation.

      • Effect of rotation on Stoneley waves in orthotropic magneto-thermoelastic media

        Parveen Lata,Himanshi 한국풍공학회 2022 Wind and Structures, An International Journal (WAS Vol.35 No.6

        The present research is concerned with the study of Stoneley wave propagation at the interface of two dissimilar homogeneous orthotropic magneto-thermoelastic solids with fractional order theory of type GN-III with three phase-lags and combined effect of hall current and rotation. With the help of appropriate boundary conditions the secular equations of Stoneley waves are obtained in the form of determinant. The characteristics of wave such as phase velocity, attenuation coefficient and specific loss are computed numerically. The effect of rotation on the Stoneley wave’s phase velocity, attenuation coefficient, specific loss, displacement components, stress components and temperature change has been depicted graphically. Some particular cases are also derived in this problem.

      • KCI등재

        Time harmonic interactions in an orthotropic media in the context of fractional order theory of thermoelasticity

        Parveen Lata,Himanshi Zakhmi 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.73 No.6

        The present investigation deals with the thermomechanical interactions in an orthotropic thermoelastic homogeneous body in the context of fractional order theory of thermoelasticity due to time harmonic sources. The application of a time harmonic concentrated and distributed sources has been considered to show the utility of the solution obtained. Assuming the disturbances to be harmonically time dependent, the expressions for displacement components, stress components and temperature change are derived in frequency domain. Numerical inversion technique has been used to determine the results in physical domain. The effect of frequency on various components has been depicted through graphs.

      • KCI등재

        Founder <i>BRCA1</i> mutations in Nepalese population

        Anurag Mehta,Himanshi Diwan,Garima Gupta,Shrinidhi Nathany,Shalini Agnihotri,Surender Dhanda 대한병리학회 2022 Journal of Pathology and Translational Medicine Vol.56 No.4

        Background: Founder mutation is a heritable genetic alteration observed with high frequency in a geographically and culturally isolated population where one or more ancestors becomes the forebearer of the altered gene. The current study reports two founder mutations in the <i>BRCA1</i> gene in the Nepalese people.Methods: Germline <i>BRCA</i> testing in all surface epithelial ovarian cancers and the selected case of breast, prostate, and pancreatic cancers has been the standard practice from 2016 to 2021. One thousand one hundred thirtythree probands were screened for germline <i>BRCA</i> variants by next generation sequencing. The variants were classified as per the American Society of Medical Genetics and Genomics recommendations. Pathogenic (class V) and likely pathogenic (class IV) were considered clinically relevant and utilized for cascade screening.Results: Nepalese population made up a subcohort of 5.12% (58/1,133) of probands tested for germline <i>BRCA1/2</i> variants. Twenty-seven of these 58 tested harbored pathogenic genetic alterations in <i>BRCA1/2</i> genes, with 23 being <i>BRCA1</i> mutant. Sixteen of 23 <i>BRCA1</i> mutant cases shared one common pathogenic mutation c.2214_2215insT (p.Lys739Ter) (NM_007294.4). Additionally, a second highly recurrent mutation in <i>BRCA1</i> gene c.5068A>T (p.Lys1690Ter) (NM_007294.4) was noted in six patients from this population.Conclusions: The overwhelming abundance of the above two variants in a geographically confined population confers these two genetic alterations a status of founder mutations amongst the people of Nepal. A more extensive population-based study to reaffirm these findings will help establish a dual site-specific germline testing similar to the “Multisite-3-assay” in Ashkenazi Jews as the primary screening tool, especially in a resource-constrained environment.

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