Deformation of Circular Tubes in Lateral Compression ( JAPAN )

Hidetoshi Kobayashi,Masashi Daimaruya 대한기계학회 1990 KSME/JSME Joint Conference Fracture and Strength Vol.1 No.1

Scoliosis Caused by Limb-Length Discrepancy in Children

Kobayashi Kazuyoshi,Ando Kei,Nakashima Hiroaki,Machino Masaaki,Morozumi Masayoshi,Kanbara Shunsuke,Ito Sadayuki,Inoue Taro,Yamaguchi Hidetoshi,Mishima Kenichi,Ishiguro Naoki,Imagama Shiro 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.6

Study Design: Single-center retrospective study in pediatric patients.Purpose: The purpose of the study was to investigate the effects of the presence and severity of leg-length discrepancy (LLD) on scoliosis in children.Overview of Literature: LLD is a common orthopedic problem that can result in standing imbalance, low back pain, and stress fractures. It may cause structural changes in the spine over time, but the exact effect of LLD on scoliosis is unknown.Methods: The subjects were 23 children with LLD ≥20 mm (range, 27–65 mm) treated at Nagoya University Hospital between 2007 and 2017. Whole spine posteroanterior standing radiographs and whole lower limb radiographs in a supine position were recorded. Data were collected for demographics, LLD, Cobb angle, pelvic obliquity, and Nash/Moe index. Scoliosis was defined as a Cobb angle ≥10°. Leg length was measured from the top of the femoral head to the middle of the tibial plafond, and LLD was defined as the difference between the left and right leg lengths.Results: The patients (nine males and 14 females) had a mean age of 14.0 years (range, 5–18 years). The average LLD was 44.3±17.2 mm, with LLDs of 20 to 39 mm, 40 to 59 mm, and ≥60 mm in 13, five, and five subjects, respectively. The average Cobb angle was 13.0°±7.0°, and 15 subjects (65%) had scoliosis. Convexity of the scoliosis was to the short leg side in all cases. The Cobb angle was significantly related to the severity of the LLD (<i>R</i>=0.736, <i>p</i><0.01), pelvic obliquity (<i>R</i>=0.966, <i>p</i><0.01), and Nash/Moe index (<i>p</i><0.05).Conclusions: LLD is a common pediatric condition that can cause scoliosis of the spine. Severe scoliosis may develop if the LLD is ≥30 mm. Long-term studies are needed to examine the effect of LLD resolution on the elimination of scoliosis.

Persistence of Denosumab Therapy among Patients with Osteoporosis

Kobayashi Kazuyoshi,Ando Kei,Machino Masaaki,Morozumi Masayoshi,Kanbara Shunsuke,Ito Sadayuki,Inoue Taro,Yamaguchi Hidetoshi,Ishiguro Naoki,Imagama Shiro 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.4

Study Design: Retrospective study in a single center.Purpose: To examine denosumab persistence in patients of different ages with severe osteoporosis in Japan.Overview of Literature: Denosumab is an antibody drug used for the treatment of osteoporosis. It is mainly used in patients with severe osteoporosis who might have high motivation for treatment, and the need for only semi-annual subcutaneous injection might improve the continuation rate. However, no English-language articles have reported on denosumab persistence in the Japanese population, including young people, despite the importance of this issue in a super-aging society. Methods: The subjects started treatment with subcutaneous denosumab in our department from July 2013 until December 2017. Persistence rates were calculated using Kaplan-Meier curves. Patients were defined as “persistent” or “non-persistent” according to the use of therapy after 60 months.Results: The study included 101 patients (84 females) with a median follow-up period of 23.6±14.2 months. The persistence rate declined to 85.3%, 78.3%, 74.1%, 71.3%, and 69.3% at 12, 24, 36, 48, and 60 months, respectively. Age at the initiation of denosumab therapy differed significantly between non-persistent (n=31) and persistent (n=70) patients (81.3 vs. 72.8 years, <i>p</i> <0.01). Persistence was significantly lower in patients aged ≥80 years than in those aged <60 and 60–79 years (both <i>p</i> <0.01). The reasons for non-persistence of denosumab therapy were transfer to another hospital (n=13), interruption of outpatient visits (n=11), dental treatment (n=4), adverse events (n=2), and patient request (n=1).Conclusions: Persistence was significantly lower in patients aged ≥80 years than in patients of other ages, and strategies promoting persistence are needed for these elderly patients.

Reduced Port Surgery for Prostate Cancer is Feasible: Comparative Study of 2-port Laparoendoscopic and Conventional 5-port Laparoscopic Radical Prostatectomy

Akita, Hidetoshi,Nakane, Akihiro,Ando, Ryosuke,Yamada, Kenji,Kobayashi, Takahiro,Okamura, Takehiko,Kohri, Kejiro Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Background: While 5-port laparoendoscopic radical prostatectomy is standard practice, efforts have been focused in developing a single port surgery for cosmetic reasons. However, this is still in the pioneering stage considering the challenging nature of the surgical procedures. We have therefore focused on reduced port surgery, using only 2-ports. In this study, we compared 2-port laparoendoscopic radical prostatectomy (2-port RP) and conventional 5-port laparoscopic radical prostatectomy (LRP) for clinically localized prostate carcinoma and evaluated the potential advantages of each. Materials and Methods: From January 2010 to December 2010, all 23 patients with clinically localized prostate cancer underwent LRP. Starting November, 2010, when we introduced the reduced port approach, we performed this procedure for 22 consecutive patients diagnosed with early-stage prostate cancer (cT1c, cT2N0). The patients were matched 1:1 to 2-port RP or LRP for age, preoperative serum PSA level, clinical stage, biopsy and pathological Gleason grade, surgical margin status, pad-free rates and post-operative pain. Results: There was a significant difference in operative time between the 2-port RP and LRP groups ($286.5{\pm}63.3$ and $351.8{\pm}72.4$ min: p=0.0019, without any variation in blood loss (including urine) ($945.1{\pm}479.6$ vs $1271.1{\pm}871.8ml$: p=0.13). The Foley catheter indwelling period was shorter in the 2 port RP group, but without significance ($5.6{\pm}1.8$ vs $8.0{\pm}5.6$ days: p=0.057) and the total perioperative complication rates for 2 port RP and LRP were comparable at 4.5% and 8.7% (p=0.58). There was an improvement in pad-free rates up to 6 months follow-up (p=0.090), and significantly improvement at 1 year (p=0.040). PSA recurrence was 1 (4.5%) in 2-port RP and 2 (8.7%) in LRP. Continuous epidural anesthesia was used in most of LRP patients (95.7%) and in early 2-port RP patients (40.9%). In these patients, average total amount of Diclofenac sodium was 27.8mg/patient in 2-port RP and 50.0mg/patient in LRP. Conclusions: Thus the reduced port approach is as efficacious as LRP in terms of many outcome measures, with significant cosmetic advantages and reduction in post surgical pain. This method can be readily performed safely and therefore can be recommended as a standard laparoscopic surgery for prostate cancer in the future.

The Predictive Value of Glycated Hemoglobin and Albumin for the Clinical Course Following Hospitalization of Patients with Febrile Urinary Tract Infection

Minoru Kobayashi,Toshitaka Uematsu,Gaku Nakamura,Hidetoshi Kokubun,Tomoya Mizuno,Hironori Betsunoh,Takao Kamai 대한감염학회 2018 Infection and Chemotherapy Vol.50 No.3

Background Diabetes is considered a risk factor for acquisition of febrile urinary tract infection (f-UTI), but information on the association of diabetes with subsequent course of the disease is lacking. Thus, we investigated the clinical variables including diabetic status which determined the clinical course in patients with community-acquired f-UTI. Materials and Methods Patients hospitalized consecutively for f-UTI between February 2016 and January 2018 were used for this single center study. The routine laboratory tests including blood glucose and glycated hemoglobin (HbA1c) were done and empiric treatment with parenteral antibiotics was commenced on admission. The clinical course such as duration of fever (DOF) and length of hospital stay (LOS) were compared among groups classified by the clinical variables. Results Among the101 patients admitted for f-UTI, 15 patients with diabetes (14.9%) experienced significantly longer febrile period and hospitalization compared to those with hyperglycemia (n = 18, 17.8%) or those without diabetes and hyperglycemia (n = 68, 67.3%). Of the laboratory parameters tested on admission and several clinical factors, the presence of diabetes and risk factors for severe complicated infection (hydronephrosis, urosepsis, and disseminated intravascular coagulopathy) as well as HbA1c and albumin were identified as predictors for LOS by univariate analysis, whereas none of the variables failed to predict DOF. In the subsequent multivariate analysis, HbA1c levels and albumin levels were isolated as independent predictors of LOS. Conclusion Patients with higher HbA1c and lower albumin levels required the longest period of hospitalization. Thus, an evaluation of diabetic and nutritional status on admission will be feasible to foretell the clinical course and better manage the subset of patients at risk of prolonged hospitalization.

Impact Force and Elastic Response of Tapered Bars in Collision with Rigid Wall ( JAPAN )

Masashi Daimaruya,Hidetoshi Kobayashi 대한기계학회 1990 KSME/JSME Joint Conference Fracture and Strength Vol.1 No.1

식물 꽃의 전개 구조

신형섭(Hyung-Seop Shin),Hidetoshi Kobayashi 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11

In this study, the folding and unfolding development patterns of two kinds of flowers was observed by using CCD video camera with time control. The tensile tests for petals and petal cylinders were carried out to explain the differences in the unfolding behavior flowers. It was found that the Young's modulus of petal ribs is much higher than that of petals. The change of the strain energy absorbed in petal ribs during unfolding of flower was also examined by using the paper. the release of strain energy absorbed in the reinforcement axes in a petal cylinder may contribute unfolding of the flowers.

Seismic Response Characteristics of Double-Decker Cylindrical Liquid Storage Tanks

Shoichi Yoshida,Makoto Tomiya,Masashi Daimaruya,Kohshi Nishida,Hidetoshi Kobayashi 대한기계학회 1997 Asia-Pacific Vibration Conference Vol.2 No.1