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박히준,이지숙,이재동,김남재,표지희,강전모,최일환,김수영,심범상,이제헌,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-
Objectives : Cinnamomi Ramulus (CR), the young twing of Cinnamomi loureirii nees, has been used for treating symptoms related to pain. rheumatic arthritis and inflammation in Korean herb medicine. This study was carried out to investigate the anti-inflammatory effect of CR in vivo and in vitro. Methods : Extracts of CR were prepared and the chemical components of the extracts were examined by gas chromatography-mass spectrometry (GC-MS). The extracts were administrated to the rat paw edema model induced by carrageenan to evaluate the anti-inflammatory effect of CR. The expressions of nitric oxide (NO). prostaglandin E2(PGE2), inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 were also quantified in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages to survey the effect of CR in vitro. The main components were cinnamaldechyde and coumarin. Results : We examined the anti-inflammatory activity of the 80% ethanol extract of Cinnamomi Ramulus in vivo by using carrageenan-induced rat paw edema model. Maximum inhibition of 54.9% was noted at the dose of 1000㎎/㎏ after 2 hours of drug administration in carrageenan-induced rat paw edema and this showed a potent anti-inflammatory effect. Conclusions : The results showed that Cinnamomi Ramulus suppressed dose-dependently LPS-induced NO production in RAW 264.7 macrophages and also decreased iNOS protein expression. Cinnamomi Ramulus also showed a significant inhibitory effect in LPS-induced PGE2 production and COX-2 expression.
박히준,이제현,김수영,심범상,구헌종,강전모,최일환,이재동,김남재,이지숙,임사비나 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-
Objective : The use of herbal therapy is becoming an increasingly attractive approach for the treatment of various inflammatory disorders. The Alpiniae officinari Rhizoma is popular in Aisa as a traditional herbal medicine. Alpiniae officinari Rhizoma is a species of the ginger family(Zingiberacease). Method : This study was performed to investigate the anti-inflammatory effect of Alpiniae officinari Rhizoma extract by the methods of "carrageenan induced paw edema" and "Lipopolysaccharide-induced inflammatory mediators in mouse macrophage RAW 264.7 cells". Result : We suggest that Alpiniae officinari Rhizoma extract decreased paw volume induced by plantar injection of carrageenan. Also Alpiniae officinari Rhizoma extract inhibited nitric oxide, prostaglandin E₂production and induced nitric oxide synthase, cyclooxygenase-2 protein expression in Mouse macrophage RAW 264.7 cells stimulated with lipopolysaccharide. Conclusion : This study shows that Alpiniae officinari Rhizoma extract seems to have anti-inflammatory effect by inhibition of nitric oxide, prostaglandin E_(2) production and nitric oxide synthase, cyclooxygenase-2 protein expression.
REGULARITY OF WEAK SOLUTIONS OF THE COMPRESSIBLE NAVIER-STOKES EQUATIONS
Choe, Hi-Jun,Jin, Bum-Ja Korean Mathematical Society 2003 대한수학회지 Vol.40 No.6
In this paper, we assume a density with integrability on the space $L^{\infty}$(0, T; $L^{q_{0}}$) for some $q_{0}$ and T > 0. Under the assumption on the density, we obtain a regularity result for the weak solutions to the compressible Navier-Stokes equations. That is, the supremum of the density is finite and the infimum of the density is positive in the domain $T^3$ ${\times}$ (0, T). Moreover, Moser type iteration scheme is developed for $L^{\infty}$ norm estimate for the velocity.
Choe, Hi Jun,Wolf, Joerg,Yang, Minsuk Springer-Verlag 2018 Mathematische Annalen Vol. No.
<P>We study the partial regularity of suitable weak solutions to the three dimensional incompressible Navier-Stokes equations. There have been several attempts to refine the Caffarelli-Kohn-Nirenberg criterion (1982). We present an improved version of the CKN criterion with a direct method, which also provides the quantitative relation in Seregin's criterion (2007).</P>
CORNER SINGULARITY AT THE MULTIPLE JUNCTION OF THE ELECTRIC TRANSMISSION
Choe, Hi-Jun,Park, Kyong-Yop,Sohn, Ayoung Korean Mathematical Society 2005 대한수학회지 Vol.42 No.6
We consider the several plane sector domains which are bonded together along common edges with vertex at the origin. Such domains appear in electric conducting problem with multi-layered heterogeneous media. Our aim is to give a structure theorem of the singularities of the electric field at the corner. Also, we provide a regularity theorem for the electric field.
Choe, Hi Jun,Kim, Hyunseok B. G. Teubner 2005 Mathematical methods in the applied sciences Vol.28 No.1
<P>We study the isentropic compressible Navier–Stokes equations with radially symmetric data in an annular domain. We first prove the global existence and regularity results on the radially symmetric weak solutions with non-negative bounded densities. Then we prove the global existence of radially symmetric strong solutions when the initial data ρ<SUB>0</SUB>, u<SUB>0</SUB> satisfy the compatibility condition <TEX>$$-\mu \Delta {\rm \bf u}_{0} -(\lambda + \mu)\nabla \,{\rm div}\,{\rm \bf u}_{0} + \nabla (A\rho_{0}^{\gamma})=\rho_{0}^{1/2}{\rm \bf g}$$</TEX> for some radially symmetric g ∈ L<SUP>2</SUP>. The initial density ρ<SUB>0</SUB> needs not be positive. We also prove some uniqueness results on the strong solutions. Copyright © 2004 John Wiley & Sons, Ltd.</P>
Meshless Method for the Stationary Incompressible Navier-Stokes Equations
Choe, Hi Jun,Kim, Do Wan,KIM, HTEA HYUN 대한수학회 2000 대한수학회지 Vol.37 No.6
This paper presents an investigation why Mn-steel high pressure gas cylinders have been failed in service. The fractured cylinders have been collected to identify the reason of the failure using various methods. The undamaged, new cylinder has also been tested for the base data. We examined the chemical compositions and fracture facets as well as the mechanical properties of the vessels. The microstructural observations of the fractured regions of the cylinder did not indicate the noticeable defects which might cause the failure. The experiments of cylinders on the compositinal and mechanical tests showed that the cylinder was in good shape according the standards of gas pressure vessel. The morphological analysis of the fracture surfaces concluded that the origin of the failure was the local weak segments induced by the external impact to the cylinder, which result in a sudden, fast fracture.
GENERATING SAMPLE PATHS AND THEIR CONVERGENCE OF THE GEOMETRIC FRACTIONAL BROWNIAN MOTION
Choe, Hi Jun,Chu, Jeong Ho,Kim, Jongeun Korean Mathematical Society 2018 대한수학회보 Vol.55 No.4
We derive discrete time model of the geometric fractional Brownian motion. It provides numerical pricing scheme of financial derivatives when the market is driven by geometric fractional Brownian motion. With the convergence analysis, we guarantee the convergence of Monte Carlo simulations. The strong convergence rate of our scheme has order H which is Hurst parameter. To obtain our model we need to convert Wick product term of stochastic differential equation into Wick free discrete equation through Malliavin calculus but ours does not include Malliavin derivative term. Finally, we include several numerical experiments for the option pricing.
HOMOGENIZATION OF THE NON-STATIONARY STOKES EQUATIONS WITH PERIODIC VISCOSITY
Choe, Hi-Jun,Kim, Hyun-Seok Korean Mathematical Society 2009 대한수학회지 Vol.46 No.5
We study the periodic homogenization of the non-stationary Stokes equations. The fundamental homogenization theorem and corrector theorem are proved under a very general assumption on the viscosity coefficients and data. The proofs are based on a weak formulation suitable for an application of classical Tartar's method of oscillating test functions. Such a weak formulation is derived by adapting an argument in Teman's book [Navier-Stokes Equations: Theory and Numerical Analysis, North-Holland, Amsterdam, 1984].