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Eunhee Kong(공은희),Syeda T. Hasan(하산시다),Hyeran Jang(장혜란),Ella M. Zimmerly(짐머리엘라),Sang-Woon Choi(최상운),Mohsen Meydani(메이다니모슨) 한국생명과학회 2015 생명과학회지 Vol.25 No.8
혈관내피세포 기능장애는 동맥경화증 발생의 초기단계이다. 비타민B군(B6, B12, 엽산)은 혈관항상성에 중요한 인자이다. 이들 비타민B군이 결핍되면 혈관항상성에 변화가 생겨 심혈관질환을 유발한다. 비타민B군 중 엽산은 내피세포에서 산화질소 항상성에 중요한 역할을 한다. 동맥경화증에 관련된 섭취엽산의 용량의존적 효과를 알기위해, C57BL/6 쥐의 대동맥이완과 간 C반응단백질 수준을 연구하였다. 본 연구는 총 54마리의 C57BL/6 쥐를 서양식이군과 대조식이군으로 나누고, 각각은 다시 엽산섭취용량(0.2, 2, 8mg/kg)에 따라 3형태의 하위집단으로 나누었다. 18개월 동안의 식이섭취후, 양군의 8mg/kg 엽산섭취용량에서는 대동맥 이완반응을 전혀 나타내지 않았고 양군의 차이도 없었다(p<0.05). 모든 엽산섭취용량(0.2, 2, 8mg/kg)에서 간 C반응단백질 수준은 대조식이군보다 서양식이군에서 더 높았다(p=0.035). 양군의 간 C반응단백질 수준은 0.2 mg/kg 엽산섭취용량에서 가장 낮았다(p<0.05). 결론적으로, C57BL/6 쥐에서 식이에 관계없이 0.2 mg/kg 엽산섭취용량만으로도 대동맥의 이완반응을 유도하고 간 C반응단백질 수준을 낮춤으로써 동맥경화증을 충분히 예방할 수 있다. Endothelial dysfunction is an initial step in atherosclerosis. B vitamins (B6, B12, and folate) are important contributing factors to vascular homeostasis. Deficiencies in these B vitamins induce cardiovascular diseases by altering vascular homeostasis. Folate plays important roles in nitric oxide homeostasis in the endothelium. To determine the dose-dependent effect of dietary folate on atherosclerosis, we studied aortic relaxation and hepatic C-reactive protein (CRP) levels in C57BL/6 mice. In this study, a total of 54 male C57BL/6, 8-wk old mice were split into 2 dietary groups (control and Western style diet). Each diet group was divided into 3 subgroups according to dietary folate dosage (0.2, 2, and 8 mg/kg). After 18 months, the relaxation response seen in aortic rings from mice fed 0.2 or 2 mg folate/kg in both diet groups. However, the aortic relaxation response was not seen and no differences were observed in mice fed 8mg folate/kg in either diet group (p<0.05). Hepatic CRP levels at all folate dosages (0.2, 2, 8 mg folate/kg) were higher in the groups fed a Western style diet than in mice fed a control diet (p=0.035). CRP levels were lower in mice fed 0.2 mg folate/kg than in mice fed 2 or 8 mg folate/kg in both diet groups (p<0.05). These results indicate that in C57BL/6 mice 0.2 mg folate/kg may be enough to prevent atherosclerosis by inducing the relaxation responses of the aorta and by reducing levels of hepatic CRP, regardless of dietary style.
SLA-Aware Resource Management for Cloud based Multimedia Service
모하메드사비르하산 ( Sabbir Hasan ),모하메드마타하리이슬람 ( Motaharul Islam ),박준영 ( Jun Young Park ),허의남 ( Eui-nam Huh ) 한국정보처리학회 2013 한국정보처리학회 학술대회논문집 Vol.20 No.1
Virtualization technology opened a new era in the field of Data intensive, Grid and Cloud Computing. Today’s Data centers are smarter than ever leveraging the Virtualization technology. In response to that, Dynamic consolidations of Virtual Machines (VMs) allow efficient resource management by live migration of VMs in the hosts. Moreover, each client typically has a service level agreement (SLA), leads to stipulation in dealing with energy-performance trade-off as aggressive consolidation may lead to performance degradation beyond the negotiation. In this paper we propose a Cloud Based CDN approach for allocation of VM that aims to maximize the client-level SLA. Our experiment result demonstrates significant enhancement of SLA at certain level.
복합 생균제가 육계의 생산성, 육질, 지방산 조성 및 면역 반응에 미치는 영향
시딕샤리프하산 ( Siddiqui Sharif Hasan ),황채연 ( Hwang Chae Yeon ),최호성 ( Choe Ho-sung ),심관섭 ( Shim Kwan-seob ) 한국유기농업학회 2020 韓國有機農業學會誌 Vol.28 No.3
This study was conducted to investigate the efficacy of mixed probiotic on the immunity, productivity index and mortality rate in the broiler. Total of 120 one-day-old Ross broilers chicks were randomly assigned into two treatments (control dietary group and probiotic-treated group) with three replications of each treatment. The probiotic group broiler had a lower mortality rate than control during the experimental period. The productivity index in the probiotic group increased significantly than the control group. The weight of the bursa of fabricius was high in the probiotic-treated group than the control group. Activated the immunity level after fed the probiotic mixed diet compared to the control group. Furthermore, the probiotic diet significantly decreased the saturated fatty the control group. Whereas the probiotic mixed diet increased the unsaturated fatty acid than the control group. Afterward, the diet including probiotic induced positive impact on broilers immunity level. This indicates that a probiotic mixed diet could be protecting the intestine from the invasion of a pathogenic organism. It would be beneficial to the poultry industries by decrease the broiler mortality rate with elevated the immunity.
COMPUTATIONAL STUDY OF TWO DIMENSIONAL FREE SURFACE SIMULATION USING LATTICE BOLTZMANN METHOD
하산(엠디캄룰)(Md. Kamrul Hasan),정노택(Rho-Taek Jung) 한국전산유체공학회 2011 한국전산유체공학회 학술대회논문집 Vol.2011 No.11
In this paper an algorithm about how to simulate two dimensional dam breaking with lattice Boltzmann method (LBM) is presented. LBM considers a typical volume element of fluid to be composed of a collection of particles that represented by a particle velocity distribution function for each fluid component at each grid point. We use the modified Lattice Boltzmann Method for incompressible fluid. We will represent detailed information on single phase flow which considers only the water instead of both air and water. Interface treatment and conservation of mass are the most important things in simulating free surface where the Interface is treated by mass exchange with the water region. We consider free surface boundary condition on the interface and bounce back boundary condition for the treatment of solid obstacles. Finally, the results of the simulation will be compared with some other methods like Volume of Fluid, Level Set Method and some exapmles related with free surface will also be provided.
A Healthcare Management Mechanism based on ICN
Kamrul Hasan(하산 캄룰),Seong-Ho Jeong(정성호) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.2
The traditional treatment of a patient has been carried out among the patient, a doctor, a nurse, or health-related instruments. Nowadays, it also relies on individual wearable devices and many other medical instruments. The means of communications between a wearable device and a device management system are therefore needed. On the other hand, information-centric networking (ICN) is a recent paradigm for the modern Internet architecture, and it is useful for faster content retrieval as well as for more secure communications compared to the exiting IP-based network architecture. A patient's health information is very important and confidential, and thus it needs to be transferred securely and immediately. In this paper, we propose a smart healthcare management mechanism based on ICN and automated procedures, which is particularly helpful for disabled and old people who are in need of immediate care.