http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Tripsianis, Gregory,Papadopoulou, Evropi,Romanidis, Konstantinos,Katotomichelakis, Michael,Anagnostopoulos, Kostas,Kontomanolis, Emmanuel,Botaitis, Sotirios,Tentes, Ioannis,Kortsaris, Alexandros Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11
The present study was conducted to investigate the prognostic significance of co-expression patterna of HER-2, IL-6, TNF-a and TGF-${\beta}1$ in breast cancer, by correlating the number of markers with positive expression with clinicopathological characteristics indicative of tumor progression and overall survival. One hundred thirty consecutive patients with primary breast cancer were prospectively included and evaluated. Serum concentrations of the above markers were measured by ELISA. Median split was used to subdivide patients with marker positive or negative expression. The presence of ${\geq}3$ positive markers was independently associated with extended lymph node (>3) involvement (aOR, 11.94, p=0.001) and lymphovascular invasion (aOR, 12.04, p=0.018), increasing the prognostic significance of each marker considered separately. Additional prognostic information regarding survival was also provided; as the number of positive markers increased, a gradually reduction of survival time was observed. In addition, patients with 4 positive markers had significantly shorter survival (25 vs 39 months, p=0.006) and a more than 4 fold increased risk of death (aHR, 4.35, p=0.003) compared to patients with 3 positive markers. Our findings suggest that the coexpression pattern of these four markers could be used clinically as a useful marker for tumor extension and outcome of breast cancer.
Damien Chaste,Emmanuel Vian,Gregory Verhoest,Pascal Blanchet 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.2
Translocation renal cell carcinoma (RCC) is a family of rare tumors recently identifiedin the pediatric and young adult population. We report the first case of a young womanfrom French West Indies with sickle cell anemia who developed a translocation RCCt(6;11)(p21;q12). Usually people with the sickle cell condition are known to develop renalmedullary carcinoma (RMC). To our knowledge, this is the first case described inthe literature of a translocation RCC associated with sickle cell disease. Here we discussthe relation between translocation RCC, RMC, and sickle cell disease.
Gonadal Tumors Developed from Consecutively Transplanted Spleens Bearing Gonad Implants
홍인철,이선,우창현,Kenny K. Kim,Jason Kim,Gregory Emmanuel,Slawomir Niewiadomski,Paul Wolf,Ruben F. Gittes 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.6
This study was conducted by consecutively transplanting spleens, which had gonads implanted previously. A total of 84 cases for infantile testicles and 106 cases for ovarian follicles were performed. In the case of ovarian implants, the results were determined by the total number of follicle implants. A modified spleen transplantation technique called double implantation of ovarian follicles was applied to increase the amount of the implants. In this technique, an extra spleen is implanted into the potential donor so that the ovarian follicles can be implanted to two different spleens, doubling the amount of implants. Through consecutive spleen transplantation, we observed the results beyond a typical rat's life span. In many of these cases, we found more aggressive forms of malignant tumor, seminoma and dysgerminoma. We present the results and discuss possible pathogenic mechanisms of tumor formation.
Christopher Pivetti,홍인철,Chang H. Yoo,이선,Kenny Kim,Gregory Emmanuel,Jason KIm,Romy Chung,Slawomir Niewiadomski,Paul Wolf,R. F. Gittes 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.6
Comparison of pancreaticoduodenal transplants (PDT) and duct-ligated pancreas transplant (DLPT) were performed using syngeneic and allogeneic studies in rats. Both DLPT and PDT allogeneic grafts showed mild rejection. DLPT groups showed disorganized pathology and acini replaced by fat. Eventually, massive fibrosis was seen in the Islets of Langerhans, as well as rejection cellular infiltrates. In both PDT groups, normal histology was observed in the same period. Thus the effect of duct occlusion is highly detrimental for the grafts.