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Christopher Pivetti,홍인철,Chang H. Yoo,이선,Kenny Kim,Gregory Emmanuel,Jason KIm,Romy Chung,Slawomir Niewiadomski,Paul Wolf,R. F. Gittes 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.6
Comparison of pancreaticoduodenal transplants (PDT) and duct-ligated pancreas transplant (DLPT) were performed using syngeneic and allogeneic studies in rats. Both DLPT and PDT allogeneic grafts showed mild rejection. DLPT groups showed disorganized pathology and acini replaced by fat. Eventually, massive fibrosis was seen in the Islets of Langerhans, as well as rejection cellular infiltrates. In both PDT groups, normal histology was observed in the same period. Thus the effect of duct occlusion is highly detrimental for the grafts.